Thierry Henry had a hat trick, 34 goals and 13 assists in 61 appearances in the Premier League against Big Six opponents in his career.

	NAME	DATE	CLUB		OPP	MIN	G	A	PK	YC	RC
1	Thierry Henry T. Henry	8/22/1999	Arsenal	vs	Man United	77	0	0	0	0	0
2	Thierry Henry T. Henry	8/28/1999	Arsenal	@	Liverpool	90	0	0	0	1	0
3	Thierry Henry T. Henry	10/23/1999	Arsenal	@	Chelsea	28	0	0	0	0	0
4	Thierry Henry T. Henry	1/24/2000	Arsenal	@	Man United	90	0	1	0	0	0
5	Thierry Henry T. Henry	2/13/2000	Arsenal	vs	Liverpool	90	0	0	0	0	0
6	Thierry Henry T. Henry	3/19/2000	Arsenal	vs	Tottenham	76	1	0	1	0	0
7	Thierry Henry T. Henry	5/6/2000	Arsenal	vs	Chelsea	90	2	0	0	1	0
8	Thierry Henry T. Henry	8/21/2000	Arsenal	vs	Liverpool	90	1	0	0	0	0
9	Thierry Henry T. Henry	9/6/2000	Arsenal	@	Chelsea	90	1	0	0	0	0
10	Thierry Henry T. Henry	10/1/2000	Arsenal	vs	Man United	90	1	0	0	0	0
11	Thierry Henry T. Henry	10/28/2000	Arsenal	vs	Man City	90	2	1	0	0	0
12	Thierry Henry T. Henry	12/18/2000	Arsenal	@	Tottenham	90	0	0	0	0	0
13	Thierry Henry T. Henry	12/23/2000	Arsenal	@	Liverpool	90	0	0	0	0	0
14	Thierry Henry T. Henry	1/13/2001	Arsenal	vs	Chelsea	90	0	0	0	0	0
15	Thierry Henry T. Henry	2/25/2001	Arsenal	@	Man United	90	1	0	0	0	0
16	Thierry Henry T. Henry	3/31/2001	Arsenal	vs	Tottenham	90	1	0	0	0	0
17	Thierry Henry T. Henry	4/11/2001	Arsenal	@	Man City	16	0	0	0	0	0
18	Thierry Henry T. Henry	9/8/2001	Arsenal	@	Chelsea	90	1	0	0	0	0
19	Thierry Henry T. Henry	11/25/2001	Arsenal	vs	Man United	90	2	0	0	0	0
20	Thierry Henry T. Henry	12/23/2001	Arsenal	@	Liverpool	89	1	0	1	0	0
21	Thierry Henry T. Henry	12/26/2001	Arsenal	vs	Chelsea	90	0	0	0	0	0
22	Thierry Henry T. Henry	1/13/2002	Arsenal	vs	Liverpool	90	0	0	0	0	0
23	Thierry Henry T. Henry	4/6/2002	Arsenal	vs	Tottenham	90	0	0	0	0	0
24	Thierry Henry T. Henry	9/10/2002	Arsenal	vs	Man City	90	1	0	0	0	0
25	Thierry Henry T. Henry	11/16/2002	Arsenal	vs	Tottenham	75	1	1	0	0	0
	Total					5,181	34	13	3	5	0