Manchester City had their lowest goal differential in a Premier League match against Middlesbrough on May 11, 2008, with a differential of -7 goals.

man city biggest loss in a game

	CLUB	GD	DATE		OPP	RESULT	G	SH	SOT	PASS	PASS-ATT	POSS%	FOUL	YC	RC	SUBS
1	Man City	-7	5/11/2008	@	Middlesbrough	L 1-8	1	8	2		390	48.5	9	1	1	3
2	Man City	-6	10/27/2007	@	Chelsea	L 0-6	0	9	4		354	42.1	14	2	0	3
3	Man City	-6	10/28/1995	@	Liverpool	L 0-6	0							4	0	2
4	Man City	-5	3/22/2003	@	Chelsea	L 0-5	0							2	1	3
5	Man City	-5	10/28/2000	@	Arsenal	L 0-5	0							2	1	1
6	Man City	-5	11/10/1994	@	Man United	L 0-5	0							6	0	0
7	Man City	-4	2/2/2025	@	Arsenal	L 1-5	1	7	4	428	475	54.5	7	0	0	2
8	Man City	-4	11/23/2024	vs	Tottenham	L 0-4	0	23	5	527	566	58.4	19	4	0	3
9	Man City	-4	1/15/2017	@	Everton	L 0-4	0	13	5	593	672	70.8	7	2	0	1
10	Man City	-4	10/21/2006	@	Wigan Athletic	L 0-4	0	11	2		357	52.1	14	1	0	2
11	Man City	-4	2/22/2003	vs	Arsenal	L 1-5	1							0	0	2
12	Man City	-4	4/11/2001	vs	Arsenal	L 0-4	0							2	0	2
13	Man City	-4	1/13/2001	vs	Leeds United	L 0-4	0							5	0	3
14	Man City	-4	8/19/2000	@	Charlton	L 0-4	0							3	0	1
15	Man City	-4	2/19/1994	@	Coventry	L 0-4	0							3	0	2
16	Man City	-3	9/27/2020	vs	Leicester	L 2-5	2	16	5	606	670	72.3	13	1	0	2
17	Man City	-3	3/2/2016	@	Liverpool	L 0-3	0	4	1	359	478	50.4	14	1	0	3
18	Man City	-3	11/21/2015	vs	Liverpool	L 1-4	1	11	3	414	536	58.4	5	0	0	3
19	Man City	-3	9/26/2015	@	Tottenham	L 1-4	1	22	8	370	485	54.0	6	1	0	3
20	Man City	-3	4/11/2011	@	Liverpool	L 0-3	0	12	2		465	46.9	3	0	0	3
21	Man City	-3	10/24/2010	vs	Arsenal	L 0-3	0	10	4		356	34.7	11	2	1	3
22	Man City	-3	12/16/2009	@	Tottenham	L 0-3	0	11	3		448	51.7	10	3	0	2
23	Man City	-3	1/20/2007	vs	Rovers	L 0-3	0	16	6		384	50.2	14	1	0	3
24	Man City	-3	8/20/2006	@	Chelsea	L 0-3	0	8	2		361	41.9	16	4	1	3
25	Man City	-3	11/22/2003	@	Newcastle	L 0-3	0							2	0	3