David Seaman has made the most career appearances by an Arsenal player in the Premier League against Chelsea, with 19 appearances.

most appearances by a player in arsenal vs chelsea

	NAME	M	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	David Seaman D. Seaman	19	1,710	19	0	0.00	0	0	0
2	Lee Dixon L. Dixon	18	1,499	17	1	0.06	0	1	0
3	Dennis Bergkamp D. Bergkamp	17	1,161	13	4	0.24	4	8	0
4	Ray Parlour R. Parlour	17	1,362	16	0	0.00	0	0	0
5	Martin Keown M. Keown	17	1,438	16	1	0.06	0	1	0
6	Theo Walcott T. Walcott	16	941	11	4	0.25	1	5	0
7	Laurent Koscielny L. Koscielny	14	1,215	14	1	0.07	0	1	0
8	Cesc Fàbregas C. Fàbregas	13	1,155	13	1	0.08	4	5	0
9	Tony Adams T. Adams	13	1,157	13	0	0.00	2	2	0
10	Héctor Bellerín H. Bellerín	12	921	11	2	0.17	2	4	0	0	6	3	0	683	16	0
11	Bacary Sagna B. Sagna	12	1,047	12	1	0.08	1	2	0
12	Robin van Persie R. van Persie	12	782	8	5	0.42	1	6	0
13	Kolo Touré K. Touré	12	969	10	1	0.08	0	1	0
14	Thierry Henry T. Henry	12	1,018	11	8	0.67	1	9	0
15	Nigel Winterburn N. Winterburn	12	1,022	11	1	0.08	2	3	0
16	Bukayo Saka B. Saka	11	904	11	2	0.18	3	5	1	0	18	6	0	547	40	1
17	Granit Xhaka G. Xhaka	11	913	10	1	0.09	2	3	0	1	14	4	0	705	15	0
18	Mesut Özil M. Özil	11	904	11	1	0.09	0	1	0
19	Aaron Ramsey A. Ramsey	11	816	9	0	0.00	0	0	0
20	Lauren	11	921	10	0	0.00	0	0	0
21	Robert Pirès R. Pirès	11	874	10	1	0.09	1	2	0
22	Ian Wright I. Wright	11	842	9	7	0.64	3	10	1
23	Gabriel Martinelli G. Martinelli	10	627	7	2	0.20	0	2	0	0	16	7	0	278	31	3
24	Olivier Giroud O. Giroud	10	467	5	1	0.10	0	1	0
25	Tomáš Rosický T. Rosický	10	415	4	0	0.00	0	0	0