Sergio Agüero has scored the most career goals in the Premier League versus Chelsea, with 10 goals.

most goals by a player scored against chelsea in history

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Sergio Agüero S. Agüero	10	16	1,239	15	0.63	3	13	3
2	Thierry Henry T. Henry	8	12	1,018	11	0.67	1	9	0
3	Alan Shearer A. Shearer	8	18	1,620	18	0.44	4	12	0
4	Christian Benteke C. Benteke	7	13	828	9	0.54	2	9	0
5	Carlos Tévez C. Tévez	7	9	601	6	0.78	1	8	1
6	Robin van Persie R. van Persie	7	16	1,142	12	0.44	1	8	0
7	Louis Saha L. Saha	7	16	902	9	0.44	0	7	2
8	Emile Heskey E. Heskey	7	28	2,265	25	0.25	2	9	0
9	Dion Dublin D. Dublin	7	20	1,409	16	0.35	2	9	0
10	Teddy Sheringham T. Sheringham	7	20	1,357	14	0.35	3	10	2
11	Ian Wright I. Wright	7	12	932	10	0.58	3	10	1
12	Sadio Mané S. Mané	6	16	1,175	13	0.38	1	7	0	0	29	17	0	765	42	10
13	Harry Kane H. Kane	6	16	1,366	15	0.38	1	7	0	0	41	18	2	650	44	5
14	Steven Naismith S. Naismith	6	7	584	6	0.86	0	6	0
15	Gylfi Þór Sigurðsson G. Þór Sigurðsson	6	19	1,549	18	0.32	1	7	2
16	Danny Welbeck D. Welbeck	6	18	999	10	0.33	2	8	0
17	Wayne Rooney W. Rooney	6	25	1,994	22	0.24	2	8	2
18	Jermain Defoe J. Defoe	6	25	1,625	17	0.24	2	8	1
19	Craig Bellamy C. Bellamy	6	15	1,171	14	0.40	1	7	1
20	James Beattie J. Beattie	6	19	1,258	16	0.32	3	9	1
21	Paul Scholes P. Scholes	6	26	1,898	23	0.23	0	6	0
22	Andy Cole A. Cole	6	24	1,971	22	0.25	3	9	0
23	Callum Robinson C. Robinson	5	3	209	2	1.67	0	5	0	0	9	5	0	79	8	1
24	Mohamed Salah M. Salah	5	16	1,299	15	0.31	4	9	2	0	42	15	1	787	109	6
25	Dele Alli D. Alli	5	10	648	7	0.50	2	7	0	0	10	6	0	405	23	3