Sergio Agüero and Wayne Rooney are tied for having the most career goals in the Premier League against Newcastle, with 15 goals.

most goals by a player vs newcastle all-time

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Sergio Agüero S. Agüero	15	14	921	11	1.07	3	18	3
2	Wayne Rooney W. Rooney	15	24	1,960	23	0.63	8	23	1
3	Michael Owen M. Owen	13	10	801	9	1.30	1	14	1
4	Andy Cole A. Cole	11	18	1,444	17	0.61	5	16	0
5	Mohamed Salah M. Salah	10	18	1,370	15	0.56	9	19	2
6	Olivier Giroud O. Giroud	9	14	664	6	0.64	1	10	0
7	Raheem Sterling R. Sterling	9	20	1,516	17	0.45	1	10	0
8	Harry Kane H. Kane	9	16	1,287	14	0.56	3	12	0
9	Ruud van Nistelrooy R. van Nistelrooy	9	9	685	8	1.00	0	9	2
10	Paul Scholes P. Scholes	9	26	1,869	19	0.35	2	11	0
11	Robin van Persie R. van Persie	8	14	1,034	12	0.57	3	11	1
12	Jermain Defoe J. Defoe	8	24	1,363	13	0.33	1	9	0
13	Steven Gerrard S. Gerrard	8	26	2,064	24	0.31	7	15	1
14	Frank Lampard F. Lampard	8	29	2,259	25	0.28	7	15	3
15	Robbie Fowler R. Fowler	8	20	1,397	15	0.40	4	12	2
16	Romelu Lukaku R. Lukaku	7	13	886	10	0.54	4	11	1
17	Eden Hazard E. Hazard	7	11	962	11	0.64	3	10	4
18	Daniel Sturridge D. Sturridge	7	13	800	9	0.54	1	8	0
19	Cristiano Ronaldo C. Ronaldo	7	13	989	11	0.54	2	9	0
20	Ian Wright I. Wright	7	10	851	10	0.70	1	8	0
21	Les Ferdinand L. Ferdinand	7	14	958	11	0.50	1	8	0
22	Dominic Calvert-Lewin D. Calvert-Lewin	6	16	977	10	0.38	1	7	1	0	35	17	1	405	67	10
23	Ross Barkley R. Barkley	6	18	907	9	0.33	2	8	2
24	David Silva D. Silva	6	16	1,263	15	0.38	7	13	0
25	Emmanuel Adebayor E. Adebayor	6	12	840	9	0.50	6	12	0