Between the 2019-20 and 2028-29 seasons, Eddie Nketiah made the most appearances by a player off the bench in the Premier League, with 95 appearances.

most sub appearances by a player in premier league 2020s

	NAME	M	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Eddie Nketiah E. Nketiah	95	1,361	0	5	0.05	5	10	0	0	62	21	5	780	136	9
2	Adama Traoré A. Traoré	91	2,134	0	5	0.05	6	11	0	0	48	17	4	1,369	133	12
3	James Milner J. Milner	78	1,109	0	2	0.03	2	4	2	0	8	4	0	1,232	29	1
4	Tom Cairney T. Cairney	75	1,419	0	2	0.03	2	4	0	0	27	9	1	1,607	52	0
5	Danny Ings D. Ings	68	1,167	0	6	0.09	4	10	1	0	52	15	2	583	107	7
6	Jacob Murphy J. Murphy	65	1,131	0	2	0.03	5	7	0	0	31	7	4	766	66	2
7	Jay Rodriguez J. Rodriguez	65	1,221	0	2	0.03	2	4	0	0	52	11	3	551	64	17
8	Joe Willock J. Willock	64	1,147	0	5	0.08	2	7	0	0	31	11	0	772	68	3
9	Harry Wilson H. Wilson	61	1,157	0	9	0.15	3	12	0	2	47	17	3	860	78	3
10	Harvey Barnes H. Barnes	61	1,462	0	8	0.13	6	14	0	0	60	30	0	886	125	3
11	Harvey Elliott H. Elliott	60	1,080	0	1	0.02	3	4	0	0	49	14	3	1,080	60	2
12	Jeffrey Schlupp J. Schlupp	58	897	0	5	0.09	3	8	0	0	22	12	1	560	41	0
13	Adam Lallana A. Lallana	57	899	0	1	0.02	1	2	0	0	14	5	1	934	59	1
14	Curtis Jones C. Jones	56	1,006	0	1	0.02	5	6	0	0	26	5	0	1,013	48	5
15	Lucas Moura L. Moura	56	901	0	2	0.04	2	4	0	0	20	9	0	717	44	1
16	Emile Smith Rowe E. Smith Rowe	54	925	0	5	0.09	2	7	0	0	31	16	1	688	44	2
17	Leandro Trossard L. Trossard	54	1,347	0	8	0.15	4	12	0	0	41	13	2	907	103	9
18	Mateo Kovačić M. Kovačić	54	1,250	0	1	0.02	1	2	0	0	22	5	0	1,496	12	0
19	Danny Welbeck D. Welbeck	54	1,263	0	11	0.20	1	12	0	0	54	23	1	579	102	4
20	Sean Longstaff S. Longstaff	54	876	0	0	0.00	2	2	0	0	10	4	0	577	18	0
21	Jean-Philippe Mateta J. Mateta	51	884	0	4	0.08	3	7	1	0	31	13	0	382	61	8
22	Callum Hudson-Odoi C. Hudson-Odoi	51	1,148	0	3	0.06	3	6	0	0	24	7	0	933	69	8
23	Diogo Jota D. Jota	51	1,087	0	11	0.22	2	13	0	0	57	19	2	731	122	1
24	Neal Maupay N. Maupay	51	957	0	1	0.02	1	2	0	0	32	9	1	498	59	5
25	Callum Wilson C. Wilson	50	1,148	0	8	0.16	3	11	0	0	40	22	1	437	92	13