The Houston Astros scored their most runs in a game versus the Red Sox on August 28, 2023 and on May 17, 2022, with 13 runs.

Interpreted as:

astro versus red sox scoring in a regular-season game record

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	13	8/28/2023	HOU	@	BOS	W 13-5	43	18	2	1	3	12	7	3	7	1	0	54	31	6	0	1	0	1	.419	.519	.721	1.239
2	Astros	13	5/17/2022	HOU	@	BOS	W 13-4	43	15	2	0	6	13	1	1	8	0	0	45	35	8	0	0	0	1	.349	.378	.814	1.192
3	Astros	12	9/28/2017	HOU	@	BOS	W 12-2	44	17	4	0	3	11	6	0	10	0	0	50	30	7	0	0	1	0	.386	.460	.682	1.142
4	Astros	12	7/3/2015	HOU	@	BOS	W 12-8	48	17	3	0	1	11	4	1	9	2	0	53	23	4	0	0	0	0	.354	.415	.479	.894
5	Astros	11	5/31/2021	HOU	vs	BOS	W 11-2	33	13	1	0	1	10	6	1	9	1	0	41	17	2	0	1	0	2	.394	.488	.515	1.003
6	Astros	11	6/28/2008	HOU	vs	BOS	W 11-10	36	14	2	0	3	10	2	1	6	1	0	40	25	5	1	0	0	0	.389	.436	.694	1.130
7	Astros	10	8/11/2024	HOU	@	BOS	W 10-2	39	13	3	0	3	9	4	1	8	1	0	44	25	6	0	0	1	2	.333	.409	.641	1.050
8	Astros	10	8/6/2013	HOU	vs	BOS	L 10-15	35	11	0	1	3	8	4	1	8	2	1	41	22	4	1	0	0	1	.314	.400	.629	1.029
9	Astros	9	8/21/2023	HOU	vs	BOS	W 9-4	41	16	3	0	3	9	3	0	8	0	0	45	28	6	0	1	0	0	.390	.422	.683	1.105
10	Astros	9	5/15/2016	HOU	@	BOS	L 9-10	37	8	2	0	2	8	5	1	10	3	0	43	16	4	0	0	0	0	.216	.326	.432	.758
11	Astros	8	8/9/2024	HOU	@	BOS	W 8-4	41	16	2	1	2	7	3	1	4	0	0	45	26	5	0	0	1	3	.390	.444	.634	1.079
12	Astros	8	6/10/2021	HOU	@	BOS	L 8-12	35	10	2	0	2	8	4	0	9	0	0	39	18	4	0	0	0	1	.286	.359	.514	.873
13	Astros	8	6/9/2021	HOU	@	BOS	W 8-3	42	17	7	0	2	8	4	0	8	0	0	47	30	9	0	1	0	0	.405	.447	.714	1.161
14	Astros	8	4/23/2016	HOU	vs	BOS	W 8-3	35	12	6	0	1	8	5	1	8	0	0	41	21	7	0	0	1	0	.343	.439	.600	1.039
15	Astros	8	7/21/2015	HOU	vs	BOS	W 8-3	31	9	2	1	1	6	4	2	6	2	0	38	16	4	0	1	0	1	.290	.395	.516	.911
16	Astros	8	8/17/2014	HOU	@	BOS	W 8-1	35	11	0	0	3	8	6	0	7	0	0	42	20	3	0	1	0	2	.314	.405	.571	.976
17	Astros	7	8/30/2023	HOU	@	BOS	W 7-4	37	12	3	1	0	7	4	0	7	0	0	41	17	4	0	0	0	1	.324	.390	.459	.850
18	Astros	7	8/22/2023	HOU	vs	BOS	W 7-3	33	8	3	0	1	7	5	0	6	1	0	39	14	4	1	0	0	1	.242	.342	.424	.766
19	Astros	7	6/8/2021	HOU	@	BOS	W 7-1	35	11	3	0	2	7	7	1	10	0	0	43	20	5	0	0	1	3	.314	.442	.571	1.013
20	Astros	7	5/18/2019	HOU	@	BOS	W 7-3	37	13	3	1	1	7	6	0	4	0	0	45	21	5	0	2	0	1	.351	.422	.568	.990
21	Astros	7	6/1/2018	HOU	vs	BOS	W 7-3	35	12	0	0	3	6	3	0	6	0	0	38	21	3	0	0	0	1	.343	.395	.600	.995
22	Astros	7	6/17/2017	HOU	vs	BOS	W 7-1	32	11	5	0	2	6	1	0	5	0	0	35	22	7	0	2	0	1	.344	.343	.688	1.030
23	Astros	7	5/13/2016	HOU	@	BOS	W 7-6	39	13	3	0	1	7	4	0	11	2	0	43	19	4	0	0	0	0	.333	.395	.487	.883
24	Astros	7	8/16/2014	HOU	@	BOS	L 7-10	37	12	1	0	2	7	5	1	3	0	1	44	19	3	0	1	0	0	.324	.409	.514	.923
25	Astros	6	8/29/2023	HOU	@	BOS	W 6-2	35	9	3	0	2	6	4	0	3	1	1	39	18	5	0	0	1	1	.257	.333	.514	.848