The San Francisco Giants had the best record by a team in their first 81 games in 2021, with a record of 51-30.

	TEAM	REC	SEASON	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Giants	51-30	2021	.630	81	51	30	2,686	399	649	125	13	121	379	311	26	770	35	9	3,056	1,163	259	20	13	18	65	.242	.325	.433	.758
2	Red Sox	50-31	2021	.617	81	50	31	2,735	410	710	173	9	102	385	225	36	707	30	11	3,024	1,207	284	4	24	9	49	.260	.322	.441	.763
3	Dodgers	50-31	2021	.617	81	50	31	2,689	408	643	119	15	105	388	347	55	711	24	8	3,124	1,107	239	18	15	20	54	.239	.336	.412	.748
4	White Sox	49-32	2021	.605	81	49	32	2,631	404	668	131	14	82	376	308	37	701	35	14	3,016	1,073	227	15	25	2	58	.254	.338	.408	.745
5	Astros	48-33	2021	.593	81	48	33	2,790	454	770	154	6	103	434	307	37	592	26	10	3,177	1,245	263	5	38	14	79	.276	.351	.446	.797
6	Padres	48-33	2021	.593	81	48	33	2,670	370	639	117	12	96	351	315	31	676	74	19	3,060	1,068	225	16	28	16	67	.239	.324	.400	.724
7	Brewers	48-33	2021	.593	81	48	33	2,651	350	578	115	8	98	334	303	50	790	38	13	3,036	1,003	221	15	17	14	45	.218	.308	.378	.687
8	Athletics	47-34	2021	.580	81	47	34	2,654	368	626	133	12	102	345	284	45	697	30	8	3,019	1,089	247	9	27	6	50	.236	.317	.410	.728
9	Rays	47-34	2021	.580	81	47	34	2,764	397	636	137	8	99	375	315	38	837	55	22	3,134	1,086	244	4	13	14	35	.230	.316	.393	.709
10	Mets	44-37	2021	.543	81	44	37	2,558	301	591	106	6	81	287	249	48	706	26	13	2,882	952	193	18	9	12	53	.231	.310	.372	.682
11	Blue Jays	43-38	2021	.531	81	43	38	2,773	422	738	138	7	123	400	250	22	668	39	12	3,068	1,259	268	7	16	9	66	.266	.330	.454	.784
12	Cubs	42-39	2021	.519	81	42	39	2,606	342	581	99	14	107	326	264	46	787	43	21	2,954	1,029	220	19	19	8	59	.223	.304	.395	.698
13	Indians	42-39	2021	.519	81	42	39	2,637	347	599	118	13	98	329	229	32	677	36	8	2,921	1,037	229	11	12	10	58	.227	.296	.393	.689
14	Mariners	42-39	2021	.519	81	42	39	2,618	333	572	125	5	98	323	248	32	780	37	11	2,920	1,001	228	6	16	3	45	.218	.292	.382	.675
15	Reds	41-40	2021	.506	81	41	40	2,729	400	681	137	5	106	383	280	56	710	22	17	3,100	1,146	248	17	18	10	63	.250	.330	.420	.750
16	Yankees	41-40	2021	.506	81	41	40	2,668	332	626	97	5	107	308	329	19	747	17	4	3,036	1,054	209	6	14	7	81	.235	.321	.395	.717
17	Nationals	40-41	2021	.494	81	40	41	2,624	329	657	118	7	90	314	250	38	681	37	17	2,945	1,059	215	19	14	15	69	.250	.323	.404	.727
18	Braves	40-41	2021	.494	81	40	41	2,638	380	623	133	11	115	365	291	38	762	38	13	3,006	1,123	259	17	22	19	42	.236	.319	.426	.744
19	Cardinals	40-41	2021	.494	81	40	41	2,637	319	597	124	9	84	304	241	42	656	39	13	2,954	991	217	15	19	19	46	.226	.299	.376	.675
20	Angels	40-41	2021	.494	81	40	41	2,746	401	700	148	9	113	381	225	34	701	30	9	3,033	1,205	270	18	10	16	62	.255	.318	.439	.757
21	Phillies	39-42	2021	.481	81	39	42	2,673	342	633	125	10	86	329	269	35	768	47	7	3,022	1,036	221	20	25	15	55	.237	.312	.388	.700
22	Tigers	36-45	2021	.444	81	36	45	2,651	324	620	107	17	86	313	258	21	799	50	12	2,960	1,019	210	9	21	3	51	.234	.305	.384	.689
23	Royals	34-47	2021	.420	81	34	47	2,686	334	659	117	16	81	316	221	26	654	53	15	2,966	1,051	214	12	21	6	55	.245	.307	.391	.698
24	Rockies	34-47	2021	.420	81	34	47	2,670	352	655	134	21	76	333	242	21	694	45	11	2,975	1,059	231	23	19	15	42	.245	.311	.397	.708
25	Marlins	34-47	2021	.420	81	34	47	2,692	320	626	115	13	76	303	242	34	784	55	16	3,000	995	204	11	21	12	44	.233	.302	.370	.671