Derek Jeter has scored the most career runs in the postseason, with 111 runs.

Interpreted as:

biggest playoff run by a player

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Derek Jeter D. Jeter	111	158	650	200	32	5	20	61	66	5	135	18	5	734	302	57	9	4	3	14	.308	.374	.465	.838
2	Jose Altuve J. Altuve	89	105	436	118	21	0	27	56	43	2	75	9	5	484	220	48	0	3	2	15	.271	.337	.505	.841
3	Bernie Williams B. Williams	83	121	465	128	29	0	22	80	71	3	85	8	5	545	223	51	0	6	11	17	.275	.371	.480	.850
4	Manny Ramirez M. Ramirez	67	111	410	117	19	0	29	78	72	5	91	1	1	493	223	48	0	6	12	17	.285	.394	.544	.937
5	Kenny Lofton K. Lofton	65	95	392	97	12	4	7	34	38	2	68	34	6	438	138	23	3	3	3	4	.247	.315	.352	.667
6	Alex Bregman A. Bregman	63	99	370	88	17	1	19	54	53	9	64	3	1	434	164	37	0	2	4	10	.238	.346	.443	.789
7	Chipper Jones C. Jones	58	93	338	97	18	0	13	47	72	1	61	8	3	417	154	31	1	5	11	10	.287	.409	.456	.864
8	Albert Pujols A. Pujols	57	88	304	97	18	1	19	54	50	5	46	1	2	360	174	38	0	1	20	7	.319	.422	.572	.995
9	Corey Seager C. Seager	55	78	299	76	17	1	19	48	42	3	79	3	0	346	152	37	0	2	3	6	.254	.350	.508	.858
10	David Justice D. Justice	55	112	398	89	17	2	14	63	64	5	79	3	2	471	152	33	0	4	7	7	.224	.335	.382	.717
11	Mookie Betts M. Betts	54	74	293	76	22	0	8	34	40	1	54	16	1	339	122	30	0	5	7	4	.259	.345	.416	.762
12	Jorge Posada J. Posada	53	125	416	103	23	1	11	42	70	3	109	3	3	492	161	35	0	3	9	15	.248	.358	.387	.745
13	David Ortiz D. Ortiz	51	85	304	88	22	2	17	61	59	2	72	0	1	369	165	41	0	4	11	4	.289	.404	.543	.947
14	Rickey Henderson R. Henderson	47	60	222	63	12	4	5	20	37	2	32	33	6	262	98	21	0	1	0	1	.284	.389	.441	.831
15	Carlos Beltran C. Beltran	45	65	215	66	15	1	16	42	37	2	33	11	0	256	131	32	1	1	2	3	.307	.412	.609	1.021
16	Tino Martinez T. Martinez	44	99	356	83	15	0	9	38	41	6	72	3	2	405	125	24	0	2	7	1	.233	.321	.351	.672
17	George Springer G. Springer	43	67	276	74	15	0	19	38	31	2	74	4	1	309	146	34	0	0	1	4	.268	.346	.529	.875
18	Justin Turner J. Turner	43	86	315	85	19	1	13	42	38	13	59	5	0	368	145	33	0	2	1	6	.270	.370	.460	.830
19	Andruw Jones A. Jones	43	76	238	65	8	0	10	34	34	2	50	5	5	279	103	18	1	4	2	5	.273	.363	.433	.796
20	Alex Rodriguez A. Rodriguez	43	76	278	72	16	0	13	41	39	9	77	8	3	330	127	29	1	3	4	6	.259	.365	.457	.822
21	Kyle Schwarber K. Schwarber	42	69	228	54	6	0	21	34	44	4	71	5	0	278	123	27	0	2	5	4	.237	.367	.539	.906
22	Matt Holliday M. Holliday	42	77	290	71	10	1	13	37	18	6	62	1	1	314	122	24	0	0	0	5	.245	.303	.421	.723
23	Mickey Mantle M. Mantle	42	65	230	59	6	2	18	40	43	0	54	3	4	273	123	26	0	0	6	2	.257	.374	.535	.908
24	Bryce Harper B. Harper	41	53	193	54	13	1	17	34	35	2	53	8	1	232	120	31	1	1	4	5	.280	.394	.622	1.016
25	Chase Utley C. Utley	41	68	210	47	7	1	10	27	39	8	52	11	2	258	86	18	0	1	3	4	.224	.364	.410	.774