Whitey Ford has the most career losses in the World Series, with 8 games.

Interpreted as:

biggest world series game loss by a player

	NAME	L	SERIES	W	L%	G	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Whitey Ford W. Ford	8	World Series	0	1.000	8	.000	8	6.08	24	0	0	0	40.0	50	27	29	5	8	0	0	2	175	2	5.40	1.80	3.00	1.13	13.7	4.6	1.45	.326	6.53	11.25
2	Justin Verlander J. Verlander	6	World Series	0	1.000	6	.000	6	5.91	34	0	0	0	32.0	33	21	24	7	12	1	0	0	141	2	9.56	3.38	2.83	1.97	24.1	8.5	1.41	.299	6.75	9.28
3	Schoolboy Rowe S. Rowe	5	World Series	0	1.000	5	.000	5	4.25	17	3	0	0	29.2	37	14	17	3	2	0	0	0	129	0	5.16	0.61	8.50	0.91	13.2	1.6	1.31	.318	5.16	11.22
4	Bullet Joe Bush B. Joe Bush	5	World Series	0	1.000	5	.000	4	3.54	12	3	0	0	40.2	41	16	17	2	14	0	1	2	166	0	2.66	3.10	0.86	0.44	7.2	8.4	1.35	.283	3.76	9.07
5	Christy Mathewson C. Mathewson	5	World Series	0	1.000	5	.000	5	2.01	16	4	0	0	44.2	38	10	15	1	7	0	0	2	179	0	3.22	1.41	2.29	0.20	8.9	3.9	1.01	.239	3.02	7.66
6	Rube Marquard R. Marquard	5	World Series	0	1.000	5	.000	5	5.28	18	0	0	0	29.0	29	17	20	3	9	0	0	0	126	1	5.59	2.79	2.00	0.93	14.3	7.1	1.31	.271	6.21	9.00
7	Eddie Plank E. Plank	5	World Series	0	1.000	5	.000	4	1.72	23	4	0	0	36.2	30	7	9	0	10	3	1	1	155	1	5.65	2.45	2.30	0.00	14.8	6.5	1.09	.252	2.21	7.36
8	Andy Pettitte A. Pettitte	4	World Series	0	1.000	4	.000	4	8.84	17	0	0	0	18.1	24	18	19	2	6	1	0	2	85	0	8.35	2.95	2.83	0.98	20.0	7.1	1.64	.373	9.33	11.78
9	Dave Stewart D. Stewart	4	World Series	0	1.000	4	.000	4	3.91	11	1	0	0	25.1	22	11	15	2	13	1	0	0	109	1	3.91	4.62	0.85	0.71	10.1	11.9	1.38	.244	5.33	7.82
10	Charlie Leibrandt C. Leibrandt	4	World Series	0	1.000	4	.000	2	6.75	9	0	0	0	14.2	17	11	11	2	3	1	2	1	63	0	5.52	1.84	3.00	1.23	14.3	4.8	1.36	.313	6.75	10.43
11	Ralph Terry R. Terry	4	World Series	0	1.000	4	.000	3	3.48	17	0	0	0	20.2	18	8	10	3	4	1	1	1	86	0	7.40	1.74	4.25	1.31	19.8	4.7	1.06	.246	4.35	7.84
12	Don Newcombe D. Newcombe	4	World Series	0	1.000	4	.000	4	6.64	19	1	0	0	20.1	23	15	15	7	6	0	0	0	87	0	8.41	2.66	3.17	3.10	21.8	6.9	1.43	.291	6.64	10.18
13	Paul Derringer P. Derringer	4	World Series	0	1.000	4	.000	4	5.06	21	1	0	0	21.1	25	12	17	1	9	0	0	1	99	1	8.86	3.80	2.33	0.42	21.2	9.1	1.59	.353	7.17	10.55
14	Bill Sherdel B. Sherdel	4	World Series	0	1.000	4	.000	4	3.26	6	1	0	0	30.1	30	11	12	4	11	1	0	1	131	1	1.78	3.26	0.55	1.19	4.6	8.4	1.35	.239	3.56	8.90
15	Waite Hoyt W. Hoyt	4	World Series	0	1.000	4	.000	4	1.29	12	1	0	0	28.0	29	4	10	1	6	0	0	0	117	0	3.86	1.93	2.00	0.32	10.3	5.1	1.25	.286	3.21	9.32
16	Art Nehf A. Nehf	4	World Series	0	1.000	4	.000	4	3.16	12	2	0	0	31.1	17	11	13	1	15	0	0	1	123	0	3.45	4.31	0.80	0.29	9.8	12.2	1.02	.168	3.73	4.88
17	Burleigh Grimes B. Grimes	4	World Series	0	1.000	4	.000	4	5.27	15	2	0	0	27.1	26	16	17	5	11	0	0	2	116	0	4.94	3.62	1.36	1.65	12.9	9.5	1.35	.247	5.60	8.56
18	Carl Mays C. Mays	4	World Series	0	1.000	4	.000	4	3.90	11	2	0	0	30.0	31	13	14	0	5	1	0	1	124	0	3.30	1.50	2.20	0.00	8.9	4.0	1.20	.290	4.20	9.30
19	Ed Summers E. Summers	4	World Series	0	1.000	4	.000	3	5.73	11	0	0	0	22.0	31	14	21	1	8	1	1	0	107	2	4.50	3.27	1.38	0.41	10.3	7.5	1.77	.349	8.59	12.68
20	Bill Donovan B. Donovan	4	World Series	0	1.000	4	.000	4	4.03	14	3	0	0	29.0	26	13	16	1	12	2	0	0	122	1	4.34	3.72	1.17	0.31	11.5	9.8	1.31	.269	4.97	8.07
21	Mordecai Brown M. Brown	4	World Series	0	1.000	4	.000	4	6.41	20	2	0	0	26.2	34	19	25	0	9	0	0	0	124	2	6.75	3.04	2.22	0.00	16.1	7.3	1.61	.358	8.44	11.48
22	Chief Bender C. Bender	4	World Series	0	1.000	4	.000	4	3.77	24	3	0	0	31.0	28	13	14	0	11	1	0	0	124	0	6.97	3.19	2.18	0.00	19.4	8.9	1.26	.318	4.06	8.13
23	Luis Garcia L. Garcia	3	World Series	0	1.000	3	.000	2	6.43	9	0	0	0	7.0	7	5	5	2	5	0	0	1	33	0	11.57	6.43	1.80	2.57	27.3	15.2	1.71	.294	6.43	9.00
24	Brad Lidge B. Lidge	3	World Series	0	1.000	3	.000	0	13.50	4	0	0	0	3.1	7	5	5	1	0	1	3	0	17	0	10.80	0.00		2.70	23.5	0.0	2.10	.545	13.50	18.90
25	Kevin Brown K. Brown	3	World Series	0	1.000	3	.000	3	6.16	14	0	0	0	19.0	23	13	13	1	8	0	0	2	83	0	6.63	3.79	1.75	0.47	16.9	9.6	1.63	.367	6.16	10.89