Denny McLain was 131-91 with an ERA of 3.39, 1,282 strikeouts and 2 saves in 280 appearances in his career.
- Regular season
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. McLain | 1963 | 3 | 2 | 1 | .667 | 3 | 4.29 | 22 | 2 | 0 | 0 | 21.0 | 20 | 10 | 12 | 2 | 16 | 0 | 0 | 0 | 96 | 1 | 9.43 | 6.86 | 1.38 | 0.86 | 22.9 | 16.7 | 1.71 | .321 | 5.14 | 117 | 3.91 | 106 | 8.57 | -0.5 | |
| 2 | | D. McLain | 1964 | 19 | 4 | 5 | .444 | 16 | 4.05 | 70 | 3 | 0 | 0 | 100.0 | 84 | 45 | 48 | 16 | 37 | 1 | 0 | 0 | 416 | 0 | 6.30 | 3.33 | 1.89 | 1.44 | 16.8 | 8.9 | 1.21 | .233 | 4.32 | 108 | 4.42 | 114 | 7.56 | -5.7 | |
| 3 | | D. McLain | 1965 | 33 | 16 | 6 | .727 | 29 | 2.61 | 192 | 13 | 4 | 1 | 220.1 | 174 | 64 | 73 | 25 | 62 | 2 | 2 | 1 | 881 | 3 | 7.84 | 2.53 | 3.10 | 1.02 | 21.8 | 7.0 | 1.07 | .248 | 2.98 | 75 | 3.12 | 86 | 7.11 | 12 | |
| 4 | | D. McLain | 1966 | 38 | 20 | 14 | .588 | 38 | 3.92 | 192 | 14 | 4 | 0 | 264.1 | 205 | 115 | 120 | 42 | 104 | 3 | 0 | 3 | 1,080 | 6 | 6.54 | 3.54 | 1.85 | 1.43 | 17.8 | 9.6 | 1.17 | .221 | 4.09 | 113 | 4.38 | 122 | 6.98 | -22.9 | |
| 5 | | D. McLain | 1967 | 37 | 17 | 16 | .515 | 37 | 3.79 | 161 | 10 | 3 | 0 | 235.0 | 209 | 99 | 110 | 35 | 73 | 3 | 0 | 3 | 976 | 4 | 6.17 | 2.80 | 2.21 | 1.34 | 16.5 | 7.5 | 1.20 | .247 | 4.21 | 115 | 4.07 | 119 | 8.00 | -16.6 | |
| 6 | | D. McLain | 1968 | 41 | 31 | 6 | .838 | 41 | 1.96 | 280 | 28 | 6 | 0 | 336.0 | 241 | 73 | 86 | 31 | 63 | 6 | 0 | 2 | 1,288 | 3 | 7.50 | 1.69 | 4.44 | 0.83 | 21.7 | 4.9 | 0.90 | .231 | 2.30 | 64 | 2.53 | 79 | 6.46 | 24.8 | |
| 7 | | D. McLain | 1969 | 42 | 24 | 9 | .727 | 41 | 2.80 | 181 | 23 | 9 | 0 | 325.0 | 288 | 101 | 105 | 25 | 67 | 4 | 0 | 7 | 1,304 | 5 | 5.01 | 1.86 | 2.70 | 0.69 | 13.9 | 5.1 | 1.09 | .256 | 2.91 | 76 | 3.04 | 80 | 7.98 | 27.4 | |
| 8 | | D. McLain | 1970 | 14 | 3 | 5 | .375 | 14 | 4.63 | 52 | 1 | 0 | 0 | 91.1 | 100 | 47 | 51 | 19 | 28 | 3 | 0 | 0 | 402 | 0 | 5.12 | 2.76 | 1.86 | 1.87 | 12.9 | 7.0 | 1.40 | .270 | 5.03 | 121 | 5.22 | 129 | 9.85 | -11.4 | |
| 9 | | D. McLain | 1971 | 33 | 10 | 22 | .313 | 32 | 4.28 | 103 | 9 | 3 | 0 | 216.2 | 233 | 103 | 115 | 31 | 72 | 3 | 1 | 8 | 931 | 4 | 4.28 | 2.99 | 1.43 | 1.29 | 11.1 | 7.7 | 1.41 | .280 | 4.78 | 127 | 4.39 | 127 | 9.68 | -23.8 | |
| 10 | | D. McLain | 1972 | TOT | 20 | 4 | 7 | .364 | 13 | 6.37 | 29 | 2 | 0 | 1 | 76.1 | 92 | 54 | 58 | 16 | 26 | 1 | 5 | 0 | 345 | 1 | 3.42 | 3.07 | 1.12 | 1.89 | 8.4 | 7.5 | 1.55 | .278 | 6.84 | 185 | 5.42 | 160 | 10.85 | -16.5 |
| Total | 280 | 131 | 91 | .590 | 264 | 3.39 | 1,282 | 105 | 29 | 2 | 1886.0 | 1,646 | 711 | 778 | 242 | 548 | 26 | 8 | 24 | 7,719 | 27 | 6.12 | 2.62 | 2.34 | 1.15 | 16.6 | 7.1 | 1.16 | .250 | 3.71 | 99 | 3.72 | 105 | 7.85 | -33.1 |
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