The Cleveland Guardians have a run differential of 2,257 runs all-time.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Blues	-165	1901	138	.397	54	82	4,833	666	1,311	197	68	12	523	243	48	322	125		5,200	1,680	277	76				.271	.313	.348	.660
2	Bronchos	19	1902	137	.507	69	67	4,840	686	1,401	248	68	33	582	308	35	353	140		5,303	1,884	349	120				.289	.336	.389	.726
3	Naps	60	1903	140	.550	77	63	4,773	639	1,265	231	95	31	550	259	40	588	175		5,225	1,779	357	153				.265	.308	.373	.681
4	Naps	165	1904	154	.570	86	65	5,152	647	1,340	225	90	27	553	307	46	717	178		5,669	1,826	342	164				.260	.308	.354	.662
5	Naps	-24	1905	155	.494	76	78	5,166	563	1,318	211	72	18	482	286	55	714	188		5,655	1,727	301	148				.255	.301	.334	.636
6	Naps	182	1906	157	.582	89	64	5,425	664	1,514	240	73	12	548	330	41	563	203		5,987	1,936	325	191				.279	.325	.357	.682
7	Naps	7	1907	158	.559	85	67	5,068	530	1,222	182	68	11	433	335	56	677	193		5,636	1,573	261	177				.241	.295	.310	.606
8	Naps	111	1908	157	.584	90	64	5,108	570	1,221	188	58	18	458	364	55	715	177		5,770	1,579	264	243				.239	.297	.309	.606
9	Naps	-39	1909	155	.464	71	82	5,048	493	1,216	173	81	10	407	283	48	698	173		5,536	1,581	264	157				.241	.288	.313	.601
10	Naps	-109	1910	161	.467	71	81	5,395	548	1,316	188	64	9	460	366	37	645	189		5,987	1,659	261	189				.244	.296	.308	.604
11	Naps	-17	1911	156	.523	80	73	5,321	692	1,501	238	81	20	579	354	50	647	209		5,885	1,961	339	160				.282	.333	.369	.701
12	Naps	-1	1912	155	.490	75	78	5,132	680	1,403	219	77	12	561	407	51	553	194	131	5,797	1,812	308	207				.273	.333	.353	.686
13	Naps	97	1913	155	.566	86	66	5,031	632	1,349	206	74	16	527	420	53	557	191		5,712	1,751	296	208				.268	.331	.348	.679
14	Naps	-169	1914	157	.333	51	102	5,157	539	1,262	178	70	10	438	450	39	685	167	157	5,801	1,610	258	155				.245	.310	.312	.622
15	Indians	-130	1915	154	.375	57	95	5,034	539	1,210	169	79	20	456	490	37	681	138	117	5,737	1,597	268	176				.240	.312	.317	.630
16	Indians	28	1916	157	.500	77	77	5,064	630	1,264	233	66	16	533	522	33	605	160		5,853	1,677	315	234				.250	.324	.331	.655
17	Indians	41	1917	156	.571	88	66	4,994	584	1,224	218	64	13	475	549	35	596	210		5,833	1,609	295	255				.245	.324	.322	.646
18	Indians	58	1918	129	.575	73	54	4,166	505	1,084	176	67	9	423	491	42	386	171		4,866	1,421	252	167				.260	.344	.341	.685
19	Indians	99	1919	139	.604	84	55	4,565	634	1,268	254	72	24	547	498	38	367	117		5,325	1,738	350	224				.278	.354	.381	.734
20	Indians	212	1920	154	.636	98	56	5,203	856	1,575	301	95	35	757	574	36	376	73	93	6,067	2,171	431	254				.303	.376	.417	.793
21	Indians	216	1921	154	.610	94	60	5,376	925	1,657	355	91	42	847	619	37	373	51	42	6,264	2,320	488	232				.308	.383	.432	.815
22	Indians	-50	1922	155	.506	78	76	5,291	767	1,546	320	73	32	698	550	46	333	90	58	6,089	2,108	425	202				.292	.364	.398	.762
23	Indians	141	1923	153	.536	82	71	5,277	886	1,591	301	75	59	806	626	49	381	79	79	6,150	2,219	435	198				.301	.381	.421	.801
24	Indians	-55	1924	153	.438	67	86	5,329	756	1,588	309	60	41	682	491	47	363	85	57	6,027	2,140	410	160				.298	.362	.402	.764
25	Indians	-34	1925	155	.455	70	84	5,440	783	1,613	284	58	52	697	521	28	379	90	77	6,169	2,169	394	180				.297	.361	.399	.760
	Total	2,257		19,474	.513	9,940	9,443	663,602	87,976	175,517	31,326	5,512	14,035	81,330	62,968	4,877	95,572	12,004	3,410	746,317	259,972	50,873	11,484	3,386	2,569	10,578	.264	.331	.392	.723