Since 1970, Clay Kirby has the highest Game Score, with a Game Score of 109 against the Astros on September 24, 1971.

Interpreted as:

highest game score by a player in a game since 1970

	NAME	GSC	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Clay Kirby C. Kirby	109	9/24/1971	SDP	vs	HOU		1	0.60	15	0	0	0	15.0	8	1	1	1	3	0	0	0	55	0
2	Tom Seaver T. Seaver	106	5/1/1974	NYM	@	LAD		1	0.75	16	0	0	0	12.0	3	1	1	1	2	0	0	1	41	0
3	Kerry Wood K. Wood	105	5/6/1998	CHC	vs	HOU	W	1	0.00	20	1	1	0	9.0	1	0	0	0	0	1	0	0	29	0
4	Frank Tanana F. Tanana	105	9/22/1975	CAL	vs	CWS		1	0.00	13	0	0	0	13.0	6	0	0	0	3	0	0	1	46	0
5	Max Scherzer M. Scherzer	104	10/3/2015	WSH	@	NYM	W	1	0.00	17	1	1	0	9.0	0	0	0	0	0	0	0	0	28	0
6	Frank Tanana F. Tanana	104	8/27/1976	CAL	vs	NYY		1	0.00	13	0	0	0	13.0	7	0	0	0	2	0	0	1	50	0
7	Jose DeLeon J. DeLeon	103	8/30/1989	STL	vs	CIN		1	0.00	8	0	0	0	11.0	1	0	0	0	0	0	0	0	33	0
8	Rudy May R. May	103	7/9/1971	CAL	@	OAK		1	0.00	13	0	0	0	12.0	3	0	0	0	6	0	0	1	43	0
9	Clayton Kershaw C. Kershaw	102	6/18/2014	LAD	vs	COL	W	1	0.00	15	1	1	0	9.0	0	0	0	0	0	0	0	0	28	0
10	Matt Cain M. Cain	101	6/13/2012	SFG	vs	HOU	W	1	0.00	14	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
11	Nolan Ryan N. Ryan	101	5/1/1991	TEX	vs	TOR	W	1	0.00	16	1	1	0	9.0	0	0	0	0	2	0	0	0	29	0
12	Nolan Ryan N. Ryan	101	8/17/1990	TEX	vs	CWS		1	0.00	15	0	0	0	10.0	3	0	0	0	0	1	0	0	34	0
13	Mike Paul M. Paul	101	7/14/1972	TEX	vs	CLE		1	0.00	10	0	0	0	11.0	3	0	0	0	0	0	0	0	35	0
14	Justin Verlander J. Verlander	100	9/1/2019	HOU	@	TOR	W	1	0.00	14	1	1	0	9.0	0	0	0	0	1	0	0	0	28	0
15	Gerrit Cole G. Cole	100	5/4/2018	HOU	@	ARI	W	1	0.00	16	1	1	0	9.0	1	0	0	0	1	0	0	0	29	0
16	Max Scherzer M. Scherzer	100	6/14/2015	WSH	@	MIL	W	1	0.00	16	1	1	0	9.0	1	0	0	0	1	0	0	0	29	0
17	Brandon Morrow B. Morrow	100	8/8/2010	TOR	vs	TBR	W	1	0.00	17	1	1	0	9.0	1	0	0	0	2	0	0	0	31	0
18	Randy Johnson R. Johnson	100	5/18/2004	ARI	@	ATL	W	1	0.00	13	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0
19	Curt Schilling C. Schilling	100	4/7/2002	ARI	@	MIL	W	1	0.00	17	1	1	0	9.0	1	0	0	0	2	0	0	0	29	0
20	Nolan Ryan N. Ryan	100	7/15/1973	CAL	@	DET	W	1	0.00	17	1	1	0	9.0	0	0	0	0	4	0	0	0	31	0
21	Nolan Ryan N. Ryan	100	7/9/1972	CAL	vs	BOS	W	1	0.00	16	1	1	0	9.0	1	0	0	0	1	0	0	0	29	0
22	Vida Blue V. Blue	100	7/9/1971	OAK	vs	CAL		1	0.00	17	0	0	0	11.0	7	0	0	0	0	0	0	0	40	1
23	John Means J. Means	99	5/5/2021	BAL	@	SEA	W	1	0.00	12	1	1	0	9.0	0	0	0	0	0	0	0	0	27	1
24	Lucas Giolito L. Giolito	99	8/25/2020	CWS	vs	PIT	W	1	0.00	13	1	1	0	9.0	0	0	0	0	1	0	0	0	28	0
25	Felix Hernandez F. Hernandez	99	8/15/2012	SEA	vs	TBR	W	1	0.00	12	1	1	0	9.0	0	0	0	0	0	0	0	0	27	0