Between October 6, 1975 and October 6, 2025, Rickey Henderson has scored the most runs, with 2,295 runs.

Interpreted as:

highest run by a player scored in the last 50 years

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rickey Henderson R. Henderson	2,295	3,081	10,961	3,055	510	66	297	1,115	2,190	98	1,694	1,406	335	13,346	4,588	873	30	67	61	172	.279	.401	.419	.820
2	Barry Bonds B. Bonds	2,227	2,986	9,847	2,935	601	77	762	1,996	2,558	106	1,539	514	141	12,606	5,976	1,440	4	91	688	165	.298	.444	.607	1.051
3	Alex Rodriguez A. Rodriguez	2,021	2,784	10,566	3,115	548	31	696	2,086	1,338	176	2,287	329	76	12,207	5,813	1,275	16	111	97	261	.295	.380	.550	.930
4	Derek Jeter D. Jeter	1,923	2,747	11,195	3,465	544	66	260	1,311	1,082	170	1,840	358	97	12,602	4,921	870	97	58	39	287	.310	.377	.440	.817
5	Albert Pujols A. Pujols	1,914	3,080	11,421	3,384	686	16	703	2,218	1,373	123	1,404	117	43	13,041	6,211	1,405	1	123	316	426	.296	.374	.544	.918
6	Craig Biggio C. Biggio	1,844	2,850	10,876	3,060	668	55	291	1,175	1,160	285	1,753	414	124	12,503	4,711	1,014	101	81	68	150	.281	.363	.433	.796
7	Paul Molitor P. Molitor	1,782	2,683	10,835	3,319	605	114	234	1,307	1,094	47	1,244	504	131	12,160	4,854	953	75	109	100	208	.306	.369	.448	.817
8	Johnny Damon J. Damon	1,668	2,490	9,736	2,769	522	109	235	1,139	1,003	50	1,257	408	103	10,917	4,214	866	57	71	38	93	.284	.352	.433	.785
9	Rafael Palmeiro R. Palmeiro	1,663	2,831	10,472	3,020	585	38	569	1,834	1,353	87	1,348	97	40	12,046	5,388	1,192	15	119	172	232	.288	.371	.515	.885
10	Ken Griffey Jr. K. Griffey Jr.	1,662	2,671	9,801	2,781	524	38	630	1,836	1,312	81	1,779	184	69	11,304	5,271	1,192	8	102	246	199	.284	.370	.538	.907
11	Cal Ripken Jr. C. Ripken Jr.	1,647	3,001	11,551	3,184	603	44	431	1,695	1,129	66	1,305	36	39	12,883	5,168	1,078	10	127	107	350	.276	.340	.447	.788
12	Gary Sheffield G. Sheffield	1,636	2,576	9,217	2,689	467	27	509	1,676	1,475	135	1,171	253	104	10,947	4,737	1,003	9	111	130	235	.292	.393	.514	.907
13	Eddie Murray E. Murray	1,627	3,026	11,336	3,255	560	35	504	1,917	1,333	18	1,516	110	43	12,817	5,397	1,099	2	128	222	315	.287	.359	.476	.836
14	Chipper Jones C. Jones	1,619	2,499	8,984	2,726	549	38	468	1,623	1,512	18	1,409	150	46	10,614	4,755	1,055	3	97	177	253	.303	.401	.529	.930
15	Jim Thome J. Thome	1,583	2,543	8,422	2,328	451	26	612	1,699	1,747	69	2,548	19	20	10,313	4,667	1,089	1	74	173	165	.276	.402	.554	.956
16	Carlos Beltran C. Beltran	1,582	2,586	9,768	2,725	565	78	435	1,587	1,084	51	1,795	312	49	11,031	4,751	1,078	18	110	104	203	.279	.350	.486	.837
17	Tim Raines T. Raines	1,571	2,502	8,872	2,605	430	113	170	980	1,330	42	966	808	146	10,359	3,771	713	39	76	148	142	.294	.385	.425	.810
18	Miguel Cabrera M. Cabrera	1,551	2,797	10,356	3,174	627	17	511	1,881	1,258	74	2,105	40	21	11,796	5,368	1,155	5	103	238	364	.306	.382	.518	.901
19	Manny Ramirez M. Ramirez	1,544	2,302	8,244	2,574	547	20	555	1,831	1,329	109	1,813	38	33	9,774	4,826	1,122	2	90	216	243	.312	.411	.585	.996
20	Dave Winfield D. Winfield	1,529	2,629	9,855	2,803	498	81	427	1,670	1,095	21	1,489	191	85	11,069	4,744	1,006	16	82	155	289	.284	.355	.481	.836
21	Kenny Lofton K. Lofton	1,528	2,103	8,120	2,428	383	116	130	781	945	32	1,016	622	160	9,234	3,433	629	72	65	43	111	.299	.372	.423	.794
22	Adrian Beltre A. Beltre	1,524	2,933	11,068	3,166	636	38	477	1,707	848	97	1,732	121	42	12,130	5,309	1,151	14	103	112	279	.286	.339	.480	.819
23	Jeff Bagwell J. Bagwell	1,517	2,150	7,797	2,314	488	32	449	1,529	1,401	128	1,558	202	78	9,431	4,213	969	3	102	155	221	.297	.408	.540	.948
24	Robin Yount R. Yount	1,517	2,602	10,106	2,907	541	119	240	1,328	921	46	1,235	252	94	11,278	4,406	900	89	116	92	205	.288	.346	.436	.782
25	Wade Boggs W. Boggs	1,513	2,439	9,180	3,010	578	61	118	1,014	1,412	23	745	24	35	10,740	4,064	757	29	96	180	236	.328	.415	.443	.858