David Ortiz has the most career strikeouts by a designated hitter Hall of Famer, with 1,659 strikeouts.
- Regular season
| NAME | SO | HOF | G | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | wRC | WRAA | wOBA | wRC+ | BRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Ortiz | 1,659 | 2022 | 2,307 | 8,313 | 1,362 | 2,379 | 609 | 19 | 531 | 1,716 | 1,278 | 33 | 16 | 9 | 9,714 | 4,619 | 1,159 | 2 | 88 | 206 | 227 | .286 | .380 | .556 | .936 | 1705 | 551.7 | .393 | 141 | 479.3 |
| 2 |  | E. Martinez | 927 | 2019 | 1,445 | 5,082 | 877 | 1,593 | 369 | 6 | 251 | 1,006 | 995 | 65 | 26 | 16 | 6,201 | 2,727 | 626 | 1 | 58 | 95 | 138 | .313 | .428 | .537 | .965 | 1206 | 428.4 | .414 | 152 | 418.4 |
| 3 |  | F. Thomas | 927 | 2014 | 1,404 | 4,937 | 813 | 1,385 | 280 | 6 | 296 | 959 | 926 | 62 | 15 | 10 | 5,985 | 2,565 | 582 | 0 | 60 | 63 | 123 | .281 | .396 | .520 | .916 | 1057 | 318 | .394 | 139 | 296 |
| 4 | | H. Baines | 902 | 2019 | 1,838 | 6,154 | 807 | 1,789 | 306 | 11 | 244 | 1,039 | 799 | 7 | 5 | 16 | 7,015 | 2,849 | 561 | 1 | 54 | 127 | 201 | .291 | .370 | .463 | .833 | 1048 | 212.1 | .363 | 122 | 188.7 |
| 5 |  | J. Thome | 786 | 2018 | 805 | 2,503 | 432 | 663 | 127 | 2 | 182 | 506 | 490 | 19 | 1 | 1 | 3,032 | 1,340 | 311 | 0 | 20 | 46 | 59 | .265 | .387 | .535 | .922 | 530 | 165.9 | .393 | 139 | 145.9 |
| 6 | | P. Molitor | 557 | 2004 | 1,261 | 5,054 | 843 | 1,613 | 309 | 53 | 119 | 756 | 558 | 24 | 187 | 40 | 5,713 | 2,385 | 481 | 16 | 61 | 61 | 112 | .319 | .385 | .472 | .857 | 909 | 219.6 | .375 | 126 | 183.4 |
| 7 |  | R. Jackson | 493 | 1993 | 506 | 1,677 | 217 | 369 | 57 | 6 | 72 | 231 | 232 | 14 | 11 | 8 | 1,933 | 654 | 135 | 1 | 9 | 23 | 32 | .220 | .318 | .390 | .708 | 216 | -6.3 | .316 | 95 | -12.1 |
| 8 | | D. Parker | 361 | 2025 | 534 | 2,042 | 217 | 539 | 101 | 6 | 66 | 303 | 144 | 8 | 7 | 11 | 2,221 | 850 | 173 | 0 | 27 | 29 | 51 | .264 | .311 | .416 | .727 | 254 | 8 | .321 | 102 | 5.7 |
| 9 | | E. Murray | 335 | 2003 | 588 | 2,213 | 288 | 608 | 99 | 4 | 90 | 343 | 194 | 1 | 18 | 6 | 2,435 | 985 | 193 | 0 | 27 | 23 | 71 | .275 | .330 | .445 | .775 | 310 | 9 | .336 | 101 | -0.5 |
| 10 | | D. Winfield | 272 | 2001 | 422 | 1,539 | 210 | 413 | 80 | 8 | 59 | 231 | 172 | 2 | 7 | 7 | 1,722 | 686 | 147 | 2 | 7 | 19 | 37 | .268 | .341 | .446 | .787 | 230 | 29.1 | .348 | 110 | 17.2 |
| 11 | | J. Rice | 260 | 2009 | 375 | 1,405 | 189 | 401 | 59 | 21 | 58 | 227 | 118 | 13 | 7 | 5 | 1,555 | 676 | 138 | 0 | 19 | 12 | 45 | .285 | .342 | .481 | .823 | 227 | 52.4 | .360 | 119 | 35.4 |
| 12 | | F. Robinson | 215 | 1982 | 376 | 1,196 | 190 | 302 | 61 | 3 | 64 | 199 | 207 | 20 | 6 | 3 | 1,437 | 561 | 128 | 3 | 11 | 29 | 29 | .253 | .369 | .469 | .838 | 217 | 61 | .375 | 141 | 66.1 |
| 13 |  | G. Brett | 211 | 1999 | 428 | 1,657 | 201 | 447 | 106 | 10 | 36 | 197 | 132 | 9 | 17 | 11 | 1,821 | 681 | 152 | 1 | 22 | 25 | 55 | .270 | .323 | .411 | .734 | 210 | 3.7 | .323 | 97 | -7.4 |
| 14 |  | C. Yastrzemski | 191 | 1989 | 593 | 2,059 | 245 | 550 | 109 | 4 | 69 | 318 | 268 | 6 | 3 | 7 | 2,352 | 874 | 182 | 1 | 18 | 29 | 56 | .267 | .350 | .424 | .775 | 312 | 47.5 | .346 | 107 | 20.9 |
| 15 |  | V. Guerrero | 172 | 2018 | 397 | 1,538 | 202 | 454 | 73 | 3 | 57 | 228 | 71 | 20 | 8 | 8 | 1,640 | 704 | 133 | 0 | 11 | 11 | 58 | .295 | .332 | .458 | .790 | 217 | 28.5 | .343 | 108 | 15.6 |
| 16 | | T. Oliva | 133 | 2022 | 471 | 1,608 | 155 | 446 | 49 | 2 | 43 | 223 | 115 | 21 | 2 | 3 | 1,761 | 628 | 94 | 2 | 15 | 41 | 39 | .277 | .331 | .391 | .721 | 197 | 5.1 | .323 | 98 | -3.6 |
| 17 | | H. Killebrew | 131 | 1984 | 228 | 645 | 53 | 136 | 20 | 0 | 27 | 98 | 99 | 1 | 1 | 2 | 751 | 237 | 47 | 0 | 6 | 10 | 17 | .211 | .314 | .367 | .682 | 78 | -3.5 | .313 | 92 | -6.9 |
| 18 | | F. McGriff | 125 | 2023 | 137 | 372 | 66 | 87 | 19 | 0 | 22 | 50 | 69 | 1 | 3 | 2 | 442 | 172 | 41 | 0 | 0 | 6 | 4 | .234 | .355 | .462 | .818 | 64 | 10 | .354 | 114 | 7.8 |
| 19 | | B. Williams | 112 | 1987 | 275 | 871 | 104 | 201 | 32 | 1 | 34 | 122 | 134 | 2 | 4 | 2 | 1,015 | 337 | 67 | 2 | 6 | 22 | 13 | .231 | .333 | .387 | .720 | 116 | 6.7 | .327 | 109 | 10.6 |
| 20 | | A. Dawson | 102 | 2010 | 196 | 753 | 78 | 196 | 47 | 1 | 29 | 115 | 26 | 17 | 4 | 3 | 804 | 332 | 77 | 0 | 8 | 7 | 33 | .260 | .297 | .441 | .738 | 91 | -7.3 | .318 | 86 | -14.8 |
| 21 |  | K. Griffey Jr. | 97 | 2016 | 150 | 485 | 50 | 101 | 21 | 0 | 19 | 64 | 72 | 1 | 0 | 0 | 562 | 179 | 40 | 0 | 4 | 2 | 9 | .208 | .310 | .369 | .679 | 56 | -10.9 | .303 | 84 | -10.6 |
| 22 | | O. Cepeda | 97 | 1999 | 175 | 657 | 54 | 182 | 30 | 0 | 21 | 104 | 59 | 4 | 1 | 2 | 725 | 275 | 51 | 2 | 3 | 13 | 29 | .277 | .339 | .419 | .757 | 91 | 11.2 | .339 | 106 | 5 |
| 23 |  | H. Aaron | 89 | 1982 | 222 | 736 | 67 | 171 | 24 | 2 | 22 | 95 | 105 | 1 | 0 | 2 | 851 | 265 | 48 | 1 | 8 | 4 | 23 | .232 | .326 | .360 | .686 | 92 | 0.5 | .320 | 100 | -0.5 |
| 24 | | A. Kaline | 75 | 1980 | 147 | 558 | 71 | 146 | 28 | 2 | 13 | 64 | 65 | 1 | 2 | 2 | 630 | 217 | 43 | 1 | 5 | 2 | 12 | .262 | .337 | .389 | .726 | 76 | 7.8 | .335 | 106 | 4.1 |
| 25 | | T. Simmons | 72 | 2021 | 275 | 1,025 | 104 | 254 | 51 | 4 | 16 | 128 | 87 | 4 | 4 | 1 | 1,124 | 361 | 71 | 2 | 6 | 12 | 40 | .248 | .307 | .352 | .660 | 108 | -19.1 | .295 | 82 | -23.2 |
StatMuse has season-level data for strikeouts going back to the 1891 season.
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
89 | 64 | .582 | ||
84 | 68 | .553 | 4.5 | |
76 | 77 | .497 | 13.0 | |
71 | 82 | .464 | 18.0 | |
69 | 83 | .454 | 19.5 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 95 | 57 | .625 | |
85 | 68 | .556 | 10.5 | |
75 | 77 | .493 | 20.0 | |
75 | 78 | .490 | 20.5 | |
71 | 81 | .467 | 24.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - x | 92 | 60 | .605 | |
83 | 69 | .546 | 9.0 | |
80 | 73 | .523 | 12.5 | |
64 | 89 | .418 | 28.5 | |
56 | 96 | .368 | 36.0 |
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