The New York Giants have the most series losses by a team against a pitcher in the World Series, with 69 losses against Lefty Gomez.

	TEAM	SERIES L	VS. PITCHER	SERIES	G	W%	W	L	AB	H	2B	3B	HR	RBI	BB	HBP	SO	PA	TB	XBH	SH	SF	IBB	AVG	OBP	SLG	OPS
1	Giants	69	Lefty Gomez	World Series	4	.000	0	142	127	30	6	0	2	10	13	0	17	142	42	8	2	0	0	.236	.307	.331	.638
2	Yankees	68	Art Nehf	World Series	7	.422	94	129	191	34	4	1	1	12	22	1	21	223	43	6	5	4	1	.178	.261	.225	.487
3	White Sox	40	Hod Eller	World Series	2	.000	0	71	68	13	3	2	1	4	2	1	15	71	23	6	0	0	0	.191	.225	.338	.564
4	Pirates	39	Wilcy Moore	World Series	2	.000	0	45	41	11	0	0	0	4	2	0	2	45	11	0	1	1	1	.268	.295	.268	.564
5	Cardinals	39	Waite Hoyt	World Series	5	.302	49	113	150	40	6	0	2	14	7	0	25	162	52	8	1	4	0	.267	.292	.347	.639
6	Cubs	39	Doc White	World Series	3	.219	14	50	54	12	3	0	0	6	7	1	4	64	15	3	2	0	1	.222	.323	.278	.600
7	Braves	38	Jack Morris	World Series	5	.528	75	67	125	31	7	0	4	12	15	0	27	142	50	11	2	0	2	.248	.329	.400	.729
8	Yankees	38	Bob Gibson	World Series	3	.319	36	77	102	23	3	0	4	11	8	2	31	113	38	7	0	1	2	.225	.292	.373	.665
9	Cubs	38	Hal Newhouser	World Series	3	.180	16	73	83	25	7	2	0	13	4	0	22	89	36	9	2	0	1	.301	.333	.434	.767
10	Cardinals	38	Spud Chandler	World Series	4	.265	27	75	94	22	1	0	0	4	4	0	13	102	23	1	4	0	0	.234	.265	.245	.510
11	Cubs	38	Red Ruffing	World Series	3	.000	0	114	106	27	4	2	1	8	8	0	21	114	38	7	0	0	1	.255	.307	.358	.666
12	Dodgers	37	Vic Raschi	World Series	8	.402	70	104	157	38	8	1	4	15	16	0	34	174	60	13	1	0	1	.242	.312	.382	.694
13	Cubs	37	Tommy Bridges	World Series	3	.119	10	74	77	21	4	1	1	8	7	0	10	84	30	6	0	0	0	.273	.333	.390	.723
14	Dodgers	36	Mike Torrez	World Series	2	.000	0	73	68	16	1	1	2	7	5	0	15	73	25	4	0	0	0	.235	.288	.368	.655
15	Yankees	36	Lew Burdette	World Series	6	.299	59	138	185	43	5	0	6	16	8	0	25	197	66	11	3	1	4	.232	.263	.357	.620
16	Yankees	36	Johnny Beazley	World Series	2	.000	0	73	70	17	2	0	2	5	3	0	6	73	25	4	0	0	0	.243	.274	.357	.631
17	Tigers	36	Paul Derringer	World Series	6	.354	40	73	92	22	4	1	0	15	17	0	7	113	28	5	4	0	4	.239	.358	.304	.662
18	Athletics	36	Burleigh Grimes	World Series	4	.489	65	68	116	19	1	2	4	11	15	0	24	133	36	7	1	1	1	.164	.258	.310	.568
19	Giants	36	Red Faber	World Series	4	.267	27	74	95	21	1	1	1	6	3	2	9	101	27	3	1	0	0	.221	.260	.284	.544
20	Phillies	36	Rube Foster	World Series	2	.000	0	66	62	12	3	0	1	4	2	2	13	66	18	4	0	0	0	.194	.242	.290	.533
21	Cubs	36	Jack Coombs	World Series	3	.000	0	116	96	24	9	0	0	8	14	0	17	116	33	9	4	2	0	.250	.339	.344	.683
22	Athletics	35	Orel Hershiser	World Series	2	.000	0	66	58	7	0	0	0	2	6	0	17	66	7	0	1	1	0	.121	.200	.121	.321
23	Yankees	35	Johnny Podres	World Series	4	.113	13	102	106	22	5	1	2	3	7	1	14	115	35	8	1	0	0	.208	.263	.330	.593
24	Phillies	35	Whitey Ford	World Series	1	.000	0	35	33	7	1	0	0	0	1	1	7	35	8	1	0	0	0	.212	.257	.242	.500
25	Giants	35	Chief Bender	World Series	7	.266	64	177	219	44	10	2	1	15	15	2	42	241	61	13	4	1	0	.201	.257	.279	.536