Luis Castillo has a 27-25 record with an ERA of 3.50 and 466 strikeouts in 81 appearances for the Mariners against the AL in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Castillo | 8/3/2022 | @ | W | 1 | 4.05 | 8 | 0 | 0 | 0 | 6.2 | 5 | 3 | 3 | 1 | 3 | 0 | 0 | 0 | 27 | 0 | ||
| 2 | | L. Castillo | 8/9/2022 | vs | 1 | 0.00 | 7 | 0 | 0 | 0 | 8.0 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 27 | 0 | |||
| 3 | | L. Castillo | 8/15/2022 | @ | 1 | 3.00 | 9 | 0 | 0 | 0 | 6.0 | 6 | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 25 | 0 | |||
| 4 | | L. Castillo | 8/21/2022 | @ | L | 1 | 7.20 | 5 | 0 | 0 | 0 | 5.0 | 8 | 4 | 4 | 0 | 1 | 1 | 0 | 0 | 23 | 0 | ||
| 5 | | L. Castillo | 8/27/2022 | vs | 1 | 1.50 | 10 | 0 | 0 | 0 | 6.0 | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 24 | 0 | |||
| 6 | | L. Castillo | 9/2/2022 | @ | W | 1 | 0.00 | 4 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 24 | 0 | ||
| 7 | | L. Castillo | 9/7/2022 | vs | 1 | 4.76 | 8 | 0 | 0 | 0 | 5.2 | 5 | 3 | 6 | 1 | 1 | 0 | 0 | 0 | 24 | 0 | |||
| 8 | | L. Castillo | 9/20/2022 | @ | L | 1 | 7.71 | 4 | 0 | 0 | 0 | 4.2 | 6 | 4 | 4 | 1 | 2 | 0 | 0 | 0 | 22 | 0 | ||
| 9 | | L. Castillo | 9/25/2022 | @ | 1 | 8.44 | 5 | 0 | 0 | 0 | 5.1 | 7 | 5 | 5 | 1 | 3 | 0 | 0 | 0 | 25 | 0 | |||
| 10 | | L. Castillo | 10/1/2022 | vs | W | 1 | 1.50 | 8 | 0 | 0 | 0 | 6.0 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 21 | 0 | ||
| 11 | | L. Castillo | 3/30/2023 | vs | 1 | 0.00 | 6 | 0 | 0 | 0 | 6.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19 | 0 | |||
| 12 | | L. Castillo | 4/4/2023 | vs | W | 1 | 0.00 | 6 | 0 | 0 | 0 | 5.2 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 21 | 0 | ||
| 13 | | L. Castillo | 4/28/2023 | @ | 1 | 3.60 | 4 | 0 | 0 | 0 | 5.0 | 6 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 23 | 0 | |||
| 14 | | L. Castillo | 5/5/2023 | vs | 1 | 5.14 | 5 | 0 | 0 | 0 | 7.0 | 5 | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 26 | 0 | |||
| 15 | | L. Castillo | 5/10/2023 | vs | L | 1 | 5.40 | 9 | 0 | 0 | 0 | 5.0 | 8 | 3 | 3 | 1 | 0 | 1 | 0 | 0 | 24 | 0 | ||
| 16 | | L. Castillo | 5/16/2023 | @ | L | 1 | 9.00 | 6 | 0 | 0 | 0 | 5.0 | 6 | 5 | 7 | 3 | 2 | 0 | 0 | 0 | 24 | 1 | ||
| 17 | | L. Castillo | 5/22/2023 | vs | W | 1 | 0.00 | 8 | 0 | 0 | 0 | 6.0 | 4 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 24 | 0 | ||
| 18 | | L. Castillo | 6/2/2023 | @ | L | 1 | 1.29 | 6 | 0 | 0 | 0 | 7.0 | 5 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 26 | 1 | ||
| 19 | | L. Castillo | 6/9/2023 | @ | L | 1 | 4.50 | 10 | 0 | 0 | 0 | 6.0 | 6 | 3 | 5 | 2 | 1 | 1 | 0 | 0 | 26 | 0 | ||
| 20 | | L. Castillo | 6/21/2023 | @ | L | 1 | 5.40 | 3 | 0 | 0 | 0 | 5.0 | 4 | 3 | 3 | 2 | 4 | 0 | 0 | 0 | 22 | 0 | ||
| 21 | | L. Castillo | 7/2/2023 | vs | 1 | 6.00 | 6 | 0 | 0 | 0 | 6.0 | 7 | 4 | 6 | 2 | 0 | 0 | 0 | 0 | 27 | 0 | |||
| 22 | | L. Castillo | 7/7/2023 | @ | W | 1 | 0.00 | 3 | 0 | 0 | 0 | 7.0 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 27 | 0 | ||
| 23 | | L. Castillo | 7/14/2023 | vs | L | 1 | 5.40 | 5 | 0 | 0 | 0 | 5.0 | 4 | 3 | 3 | 2 | 0 | 0 | 0 | 0 | 19 | 0 | ||
| 24 | | L. Castillo | 7/19/2023 | vs | 1 | 4.50 | 11 | 0 | 0 | 0 | 6.0 | 6 | 3 | 3 | 2 | 2 | 0 | 0 | 0 | 26 | 0 | |||
| 25 | | L. Castillo | 7/24/2023 | @ | 1 | 2.57 | 9 | 0 | 0 | 0 | 7.0 | 4 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 25 | 0 | |||
| Total | 81 | 3.50 | 466 | 0 | 0 | 0 | 475.2 | 421 | 185 | 198 | 62 | 129 | 14 | 0 | 2 | 1,951 | 4 | |||||||
LAA
OAK
CWS
KCR
HOU
TEX
TBR
MINSome of the information used here was obtained free of charge from Retrosheet.
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HR
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RBI
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AVG
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Team Pitching Leaders 
W
17
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K
204
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ERA
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Team Rankings
HR
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SO
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MLB 2025 Batting Leaders
MLB 2025 Pitching Leaders
MLB Fantasy 2025
MLB 2025 Betting
MLB 2025 Standings
| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Phillies - y | 96 | 66 | .593 | |
83 | 79 | .512 | 13.0 | |
79 | 83 | .488 | 17.0 | |
76 | 86 | .469 | 20.0 | |
66 | 96 | .407 | 30.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 97 | 65 | .599 | |
 Cubs - w | 92 | 70 | .568 | 5.0 |
 Reds - w | 83 | 79 | .512 | 14.0 |
78 | 84 | .481 | 19.0 | |
71 | 91 | .438 | 26.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 93 | 69 | .574 | |
 Padres - w | 90 | 72 | .556 | 3.0 |
81 | 81 | .500 | 12.0 | |
80 | 82 | .494 | 13.0 | |
43 | 119 | .265 | 50.0 |
Mets
Marlins
Braves
Nationals
Giants
Diamondbacks
Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Blue Jays - y | 94 | 68 | .580 | |
 Yankees - w | 94 | 68 | .580 | |
 Red Sox - w | 89 | 73 | .549 | 5.0 |
77 | 85 | .475 | 17.0 | |
75 | 87 | .463 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 88 | 74 | .543 | |
 Tigers - w | 87 | 75 | .537 | 1.0 |
82 | 80 | .506 | 6.0 | |
70 | 92 | .432 | 18.0 | |
60 | 102 | .370 | 28.0 | |
| AL West | W | L | PCT | GB |
 Mariners - y | 90 | 72 | .556 | |
87 | 75 | .537 | 3.0 | |
81 | 81 | .500 | 9.0 | |
76 | 86 | .469 | 14.0 | |
72 | 90 | .444 | 18.0 |
Orioles
