Since 2010, the Seattle Mariners have scored their most runs in a game versus the Rangers on May 30, 2012, with 21 runs.

Interpreted as:

mariners most runs in a regular-season game since 2010

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mariners	21	5/30/2012	SEA	@	TEX	W 21-8	47	20	7	0	4	20	6	0	8	1	0	54	39	11	0	1	0	0	.426	.481	.830	1.311
2	Mariners	18	9/7/2025	SEA	@	ATL	W 18-2	45	19	1	1	5	14	3	2	7	2	0	51	37	7	0	1	0	1	.422	.471	.822	1.293
3	Mariners	16	9/4/2024	SEA	@	OAK	W 16-3	42	16	7	0	1	16	4	1	6	1	0	48	26	8	0	1	0	0	.381	.438	.619	1.057
4	Mariners	16	6/2/2016	SEA	@	SDP	W 16-13	43	16	1	0	2	16	2	1	8	1	0	46	23	3	0	0	0	0	.372	.413	.535	.948
5	Mariners	16	5/31/2016	SEA	vs	SDP	W 16-4	37	14	0	0	5	16	10	1	4	0	0	48	29	5	0	0	0	1	.378	.521	.784	1.305
6	Mariners	15	7/12/2025	SEA	@	DET	W 15-7	44	19	5	0	3	15	4	1	10	2	1	50	33	8	0	1	0	0	.432	.480	.750	1.230
7	Mariners	15	8/26/2023	SEA	vs	KCR	W 15-2	37	13	1	0	7	15	7	1	7	0	0	45	35	8	0	0	0	0	.351	.467	.946	1.413
8	Mariners	15	5/21/2010	SEA	vs	SDP	W 15-8	40	15	3	0	3	15	4	0	8	0	0	45	27	6	0	1	0	0	.375	.422	.675	1.097
9	Mariners	14	6/22/2025	SEA	@	CHC	W 14-6	43	18	1	0	5	14	4	0	3	1	1	47	34	6	0	0	0	1	.419	.468	.791	1.259
10	Mariners	14	4/26/2025	SEA	vs	MIA	W 14-0	37	15	3	0	4	14	7	1	6	0	0	46	30	7	0	1	0	0	.405	.500	.811	1.311
11	Mariners	14	8/21/2023	SEA	@	CWS	W 14-2	42	15	3	0	4	12	5	2	8	1	0	49	30	7	0	0	0	0	.357	.449	.714	1.163
12	Mariners	14	6/5/2019	SEA	vs	HOU	W 14-1	36	13	1	0	5	14	6	1	8	0	0	43	29	6	0	0	0	1	.361	.465	.806	1.271
13	Mariners	14	4/25/2019	SEA	vs	TEX	W 14-2	36	14	5	0	1	14	8	1	8	0	0	47	22	6	0	2	0	0	.389	.489	.611	1.100
14	Mariners	14	6/12/2017	SEA	@	MIN	W 14-3	45	19	2	0	2	14	4	0	8	0	0	51	27	4	0	2	1	0	.422	.451	.600	1.051
15	Mariners	14	9/10/2016	SEA	@	OAK	W 14-3	40	17	4	0	1	13	5	0	6	0	0	46	24	5	0	1	1	1	.425	.478	.600	1.078
16	Mariners	14	9/5/2016	SEA	vs	TEX	W 14-6	38	14	3	0	2	13	9	0	14	2	0	48	23	5	0	1	2	0	.368	.479	.605	1.084
17	Mariners	14	7/23/2016	SEA	@	TOR	W 14-5	42	19	2	0	3	12	3	2	6	0	0	47	30	5	0	0	0	4	.452	.511	.714	1.225
18	Mariners	13	5/2/2025	SEA	@	TEX	W 13-1	43	17	4	0	3	13	3	1	3	0	0	48	30	7	0	1	0	1	.395	.438	.698	1.135
19	Mariners	13	6/23/2023	SEA	@	BAL	W 13-1	41	17	2	0	2	13	5	0	10	1	0	48	25	4	0	2	0	1	.415	.458	.610	1.068
20	Mariners	13	4/23/2022	SEA	vs	KCR	W 13-7	40	16	6	0	2	13	8	0	10	2	0	48	28	8	0	0	0	0	.400	.500	.700	1.200
21	Mariners	13	9/27/2021	SEA	vs	OAK	W 13-4	37	14	1	0	2	13	4	1	7	0	0	42	21	3	0	0	0	1	.378	.452	.568	1.020
22	Mariners	13	6/23/2019	SEA	vs	BAL	W 13-3	35	13	0	0	2	12	5	2	4	0	0	44	19	2	0	2	0	1	.371	.455	.543	.997
23	Mariners	13	4/8/2019	SEA	@	KCR	W 13-5	40	15	1	0	5	13	4	1	10	0	1	46	31	6	1	0	0	0	.375	.444	.775	1.219
24	Mariners	13	9/22/2018	SEA	@	TEX	W 13-0	41	16	5	1	3	12	6	0	7	0	0	48	32	9	0	1	0	1	.390	.458	.780	1.239
25	Mariners	13	6/23/2017	SEA	vs	HOU	W 13-3	40	16	4	0	3	9	3	1	7	0	0	44	29	7	0	0	0	0	.400	.455	.725	1.180