The Los Angeles Dodgers had the highest run differential by a team in 1977, with a differential of 187 runs.

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	187	1977	162	.605	98	64	5,589	769	1,484	223	28	191	729	588	23	896	114	62	6,327	2,336	442	83	44	67	103	.266	.336	.418	.753
2	Yankees	180	1977	162	.617	100	62	5,605	831	1,576	267	47	184	784	533	28	681	93	57	6,260	2,489	498	46	48	49	117	.281	.344	.444	.788
3	Phillies	179	1977	162	.623	101	61	5,546	847	1,548	266	56	186	795	573	38	806	135	68	6,290	2,484	508	59	74	75	121	.279	.346	.448	.794
4	Royals	171	1977	162	.630	102	60	5,594	822	1,549	299	77	146	773	522	45	687	170	87	6,268	2,440	522	49	58	50	104	.277	.340	.436	.776
5	Red Sox	147	1977	161	.602	97	64	5,510	859	1,551	258	56	213	828	528	42	905	66	47	6,184	2,560	527	45	59	38	132	.281	.345	.465	.810
6	Rangers	110	1977	162	.580	94	68	5,541	767	1,497	265	39	135	704	596	39	904	154	85	6,342	2,245	439	116	50	47	118	.270	.342	.405	.748
7	Twins	91	1977	161	.522	84	77	5,639	867	1,588	273	60	123	804	563	43	754	105	65	6,382	2,350	456	81	56	53	115	.282	.348	.417	.765
8	Reds	77	1977	162	.543	88	74	5,524	802	1,513	269	42	181	750	600	25	911	170	64	6,261	2,409	492	62	50	63	112	.274	.345	.436	.781
9	White Sox	73	1977	162	.556	90	72	5,633	844	1,568	254	52	192	809	559	34	666	42	44	6,322	2,502	498	33	63	46	120	.278	.344	.444	.788
10	Pirates	69	1977	162	.593	96	66	5,662	734	1,550	278	57	133	678	474	34	878	260	120	6,262	2,341	468	49	43	74	96	.274	.331	.413	.745
11	Orioles	66	1977	161	.602	97	64	5,494	719	1,433	231	25	148	677	560	24	945	90	51	6,173	2,158	404	48	47	50	132	.261	.329	.393	.722
12	Cardinals	49	1977	162	.512	83	79	5,527	737	1,490	252	56	96	686	489	25	823	134	112	6,136	2,142	404	66	29	71	111	.270	.330	.388	.718
13	Astros	30	1977	162	.500	81	81	5,530	680	1,405	263	60	114	638	515	40	839	187	72	6,200	2,130	437	76	39	60	98	.254	.320	.385	.705
14	Angels	-20	1977	162	.457	74	88	5,410	675	1,380	233	40	131	636	542	36	880	159	89	6,113	2,086	404	74	51	42	116	.255	.324	.386	.710
15	Tigers	-37	1977	162	.457	74	88	5,604	714	1,480	228	45	166	676	452	20	764	60	46	6,177	2,296	439	45	56	20	132	.264	.318	.410	.728
16	Giants	-38	1977	162	.463	75	87	5,497	673	1,392	227	41	134	624	568	21	842	90	59	6,215	2,103	402	78	51	61	118	.253	.323	.383	.705
17	Cubs	-47	1977	162	.500	81	81	5,604	692	1,489	271	37	111	649	534	27	796	64	45	6,286	2,167	419	69	52	59	142	.266	.330	.387	.716
18	Indians	-63	1977	161	.441	71	90	5,491	676	1,476	221	46	100	631	531	34	688	87	87	6,204	2,089	367	94	54	31	153	.269	.334	.380	.714
19	Expos	-71	1977	162	.463	75	87	5,675	665	1,474	294	50	138	622	478	21	877	88	50	6,282	2,282	482	69	39	66	125	.260	.318	.402	.720
20	Mets	-76	1977	162	.395	64	98	5,410	587	1,319	227	30	88	525	529	30	887	98	81	6,069	1,870	345	63	37	45	136	.244	.313	.346	.658
21	Brewers	-126	1977	162	.414	67	95	5,517	639	1,425	255	46	125	598	443	22	862	85	67	6,087	2,147	426	60	45	23	120	.258	.314	.389	.703
22	Padres	-142	1977	162	.426	69	93	5,602	692	1,397	245	49	120	652	602	29	1,057	133	57	6,353	2,100	414	90	30	64	102	.249	.324	.375	.699
23	Athletics	-144	1977	161	.391	63	98	5,358	605	1,284	176	37	117	548	516	36	910	176	89	6,020	1,885	330	64	46	37	111	.240	.308	.352	.660
24	Braves	-217	1977	162	.377	61	101	5,534	678	1,404	218	20	139	638	537	17	876	82	53	6,205	2,079	377	83	34	50	135	.254	.320	.376	.696
25	Blue Jays	-217	1977	161	.335	54	107	5,419	605	1,367	230	41	100	553	499	23	819	65	55	6,056	1,979	371	81	34	34	156	.252	.316	.365	.681