David Fletcher had the fewest strikeouts with 600+ at-bats in 2021, with 60 strikeouts.

Interpreted as:

MLB lowest strikeouts by a player 2021 with 600 or more ab

	NAME	SO	AB	SEASON	TM	G	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	David Fletcher D. Fletcher	60	626	2021	LAA	157	74	164	27	3	2	47	31	1	15	3	665	203	32	6	1	1	10	.262	.297	.324	.622	58	-22.7	.273	69	-25.2
2	Isiah Kiner-Falefa I. Kiner-Falefa	90	635	2021	TEX	158	74	172	25	3	8	53	28	11	20	5	677	227	36	1	2	2	11	.271	.312	.357	.670	70	-12.2	.293	82	-14.7
3	Jose Altuve J. Altuve	91	601	2021	HOU	146	117	167	32	1	31	83	66	4	5	3	678	294	64	1	6	3	9	.278	.350	.489	.839	106	23.8	.357	129	23.7
4	Tommy Edman T. Edman	95	641	2021	STL	159	91	168	41	3	11	56	38	6	30	5	691	248	55	2	4	1	4	.262	.308	.387	.695	76	-7.8	.301	89	-9.6
5	Whit Merrifield W. Merrifield	103	664	2021	KCR	162	97	184	42	3	10	74	40	4	40	4	720	262	55	0	12	1	12	.277	.317	.395	.711	82	-4.9	.306	89	-9.4
6	Freddie Freeman F. Freeman	107	600	2021	ATL	159	120	180	25	2	31	83	85	8	8	3	695	302	58	0	2	15	11	.300	.393	.503	.896	121	37.2	.379	136	32
7	Vladimir Guerrero Jr. V. Guerrero Jr.	110	604	2021	TOR	161	123	188	29	1	48	111	86	6	4	1	698	363	78	0	2	7	20	.311	.401	.601	1.002	145	60.4	.419	166	56.1
8	J.P. Crawford	114	619	2021	SEA	160	89	169	37	0	9	54	58	5	3	6	687	233	46	1	4	1	10	.273	.338	.376	.715	83	-0.2	.314	103	2.2
9	Cedric Mullins C. Mullins	125	602	2021	BAL	159	91	175	37	5	30	59	59	8	30	8	674	312	72	1	4	3	2	.291	.360	.518	.878	114	31.9	.372	136	29.4
10	Ozzie Albies O. Albies	128	629	2021	ATL	156	103	163	40	7	30	106	47	3	20	4	686	307	77	0	7	2	4	.259	.310	.488	.799	95	12.2	.336	108	7
11	Jonathan Schoop J. Schoop	133	623	2021	DET	156	85	173	30	1	22	84	37	6	2	0	674	271	53	0	8	0	15	.278	.320	.435	.755	87	5.3	.324	105	4.4
12	Paul Goldschmidt P. Goldschmidt	136	603	2021	STL	158	102	177	36	2	31	99	67	4	12	0	679	310	69	0	5	2	13	.294	.365	.514	.879	115	33.2	.373	136	31.4
13	Bo Bichette B. Bichette	137	640	2021	TOR	159	121	191	30	1	29	102	40	6	25	1	690	310	60	0	4	0	10	.298	.343	.484	.828	106	22.5	.354	122	18.2
14	Marcus Semien M. Semien	146	652	2021	TOR	162	115	173	39	2	45	102	66	3	15	1	724	351	86	0	3	0	9	.265	.334	.538	.873	120	31.9	.368	131	27.4
15	Kyle Seager K. Seager	161	603	2021	SEA	159	73	128	29	1	35	101	59	4	3	1	670	264	65	0	4	2	7	.212	.285	.438	.723	77	-3.8	.308	98	-1.4
16	Mitch Haniger M. Haniger	169	620	2021	SEA	157	110	157	23	2	39	100	54	9	1	0	691	301	64	0	8	2	12	.253	.318	.485	.804	98	14.5	.340	120	16.9
17	Salvador Perez S. Perez	170	620	2021	KCR	161	88	169	24	0	48	121	28	13	1	0	665	337	72	0	4	4	14	.273	.316	.544	.859	105	24.6	.359	125	20.4