Between the 2001 and 2024 seasons, the New York Yankees had the most wins by a team, with 2,199 wins.

Interpreted as:

MLB most team regular-season wins from 2001 to 2024

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	2,199	1,584	.581	3,785	129,247	19,193	33,741	6,361	463	5,156	18,387	13,966	1,515	27,854	2,311	712	146,354	56,496	11,980	576	1,050	719	3,061	.261	.338	.437	.775
2	Dodgers	2,153	1,633	.569	3,786	128,606	17,467	33,126	6,520	655	4,186	16,666	12,885	1,432	27,614	2,216	806	145,128	53,514	11,361	1,200	1,005	1,019	2,815	.258	.330	.416	.746
3	Cardinals	2,084	1,699	.551	3,783	128,616	17,636	33,686	6,645	568	4,107	16,792	12,422	1,515	26,718	1,804	762	144,915	53,788	11,320	1,308	1,054	1,065	2,962	.262	.332	.418	.750
4	Red Sox	2,060	1,725	.544	3,785	131,497	19,336	35,405	7,897	605	4,478	18,416	13,294	1,398	28,040	2,005	658	147,773	57,946	12,980	446	1,138	912	3,039	.269	.340	.441	.781
5	Braves	2,057	1,725	.544	3,783	129,143	17,549	33,466	6,727	575	4,293	16,776	12,574	1,234	28,651	1,809	721	145,161	54,222	11,595	1,260	950	1,013	2,925	.259	.329	.420	.748
6	Astros	1,957	1,827	.517	3,785	128,690	17,270	33,109	6,660	584	4,299	16,473	12,073	1,415	27,539	2,148	850	144,256	53,834	11,543	1,079	999	756	2,987	.257	.325	.418	.744
7	Guardians	1,956	1,827	.517	3,783	128,901	17,557	33,187	6,939	597	4,065	16,745	12,506	1,497	27,523	2,270	825	144,770	53,515	11,601	775	1,091	733	2,863	.257	.328	.415	.743
8	Giants	1,955	1,828	.517	3,784	128,772	16,358	32,787	6,606	797	3,609	15,563	11,977	1,224	27,185	1,688	709	144,253	51,814	11,012	1,231	1,049	1,174	2,958	.255	.322	.402	.724
9	Phillies	1,954	1,831	.516	3,785	129,352	17,412	32,934	6,603	747	4,255	16,614	12,755	1,436	29,100	2,428	650	145,606	53,796	11,605	1,124	939	1,084	2,622	.255	.326	.416	.742
10	Angels	1,952	1,834	.516	3,786	129,120	17,324	33,484	6,392	615	4,012	16,475	11,403	1,364	26,306	2,563	996	143,713	53,142	11,019	766	1,060	826	2,920	.259	.324	.412	.735
11	Athletics	1,939	1,846	.512	3,785	128,652	17,008	31,984	6,633	550	4,087	16,199	12,927	1,368	27,732	1,834	596	144,474	51,978	11,270	500	1,027	574	2,959	.249	.321	.404	.725
12	Twins	1,915	1,872	.506	3,787	129,828	17,527	33,748	6,818	712	3,958	16,625	12,074	1,321	27,653	1,971	808	144,935	53,864	11,488	666	1,046	718	2,944	.260	.327	.415	.742
13	Cubs	1,904	1,880	.503	3,785	128,584	16,973	32,607	6,597	682	4,245	16,161	12,273	1,501	29,708	1,868	788	144,501	53,303	11,524	1,230	913	894	2,816	.254	.324	.415	.738
14	Blue Jays	1,894	1,891	.500	3,785	129,458	17,809	33,322	6,997	552	4,588	17,006	12,145	1,356	27,389	1,816	676	144,501	55,187	12,137	518	1,024	549	3,030	.257	.325	.426	.751
15	Rays	1,890	1,895	.499	3,785	128,555	16,861	32,465	6,562	753	4,034	16,062	12,244	1,511	29,842	2,866	1,045	143,927	52,635	11,349	602	1,015	612	2,582	.253	.322	.409	.732
16	Brewers	1,887	1,899	.498	3,786	127,878	16,840	32,127	6,466	642	4,382	16,097	12,388	1,576	30,758	2,553	847	143,896	53,023	11,490	1,158	896	869	2,860	.251	.323	.415	.738
17	Mariners	1,884	1,902	.498	3,786	129,091	16,424	32,570	6,146	549	3,905	15,624	11,649	1,409	28,506	2,376	854	143,818	51,529	10,600	701	968	726	2,715	.252	.319	.399	.718
18	Mets	1,882	1,902	.497	3,784	128,284	16,495	32,326	6,398	625	3,951	15,746	12,220	1,531	27,948	2,281	758	144,183	51,827	10,974	1,213	935	997	2,808	.252	.322	.404	.726
19	Rangers	1,866	1,921	.493	3,787	130,040	18,419	33,861	6,696	620	4,718	17,544	11,720	1,399	28,487	2,319	814	144,887	55,951	12,034	677	1,051	640	2,689	.260	.326	.430	.756
20	Diamondbacks	1,837	1,949	.485	3,786	129,095	17,140	32,759	6,811	921	3,991	16,338	12,567	1,230	28,996	2,157	770	145,082	53,385	11,723	1,150	1,040	963	2,716	.254	.323	.414	.737
21	White Sox	1,816	1,970	.480	3,786	128,787	16,873	32,990	6,213	525	4,376	16,180	10,855	1,454	27,936	2,069	932	142,849	53,381	11,114	812	941	518	2,932	.256	.319	.414	.733
22	Padres	1,812	1,975	.478	3,787	127,728	15,900	31,559	6,121	680	3,638	15,123	12,479	1,181	29,361	2,313	819	143,507	49,954	10,439	1,136	983	801	2,735	.247	.318	.391	.709
23	Nationals	1,811	1,973	.479	3,784	127,829	16,421	32,550	6,612	618	3,762	15,613	12,182	1,388	27,995	2,364	895	143,752	51,684	10,992	1,377	976	975	2,913	.255	.324	.404	.728
24	Reds	1,776	2,010	.469	3,787	128,249	16,769	32,143	6,376	560	4,327	16,004	12,424	1,616	30,142	2,386	904	144,524	52,620	11,263	1,332	903	867	2,669	.251	.323	.410	.733
25	Tigers	1,762	2,019	.466	3,781	129,558	16,762	33,671	6,453	897	3,874	16,040	11,013	1,163	28,514	1,712	780	143,448	53,540	11,224	692	1,022	647	2,921	.260	.321	.413	.734