The Washington Nationals had the most runs by a team in a game in 2017, with 23 runs against the Mets on April 30, 2017.

Interpreted as:

MLB team most run in a regular-season game 2017

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Nationals	23	4/30/2017	WSH	vs	NYM	W 23-5	46	23	4	0	7	23	6	0	6	0	0	54	48	11	1	1	3	0	.500	.547	1.043	1.591
2	Marlins	22	7/26/2017	MIA	@	TEX	W 22-10	47	22	8	2	4	21	6	0	11	0	0	54	46	14	0	1	0	1	.468	.519	.979	1.497
3	Twins	20	6/13/2017	MIN	vs	SEA	W 20-7	49	28	2	0	5	19	2	0	4	0	0	51	45	7	0	0	0	1	.571	.588	.918	1.507
4	Astros	19	7/9/2017	HOU	@	TOR	W 19-1	45	17	4	0	5	16	8	1	7	1	0	54	36	9	0	0	0	1	.378	.481	.800	1.281
5	Tigers	19	4/25/2017	DET	vs	SEA	W 19-9	48	24	5	1	4	18	7	0	5	0	0	55	43	10	0	0	1	0	.500	.564	.896	1.459
6	Rockies	18	7/19/2017	COL	vs	SDP	W 18-4	43	21	1	1	5	17	3	1	6	0	0	49	39	7	0	2	0	0	.488	.510	.907	1.417
7	Nationals	18	6/24/2017	WSH	vs	CIN	W 18-3	40	19	5	0	2	17	7	0	10	0	0	51	30	7	1	3	0	0	.475	.520	.750	1.270
8	White Sox	17	9/14/2017	CWS	@	DET	W 17-7	51	25	2	0	2	16	5	1	10	1	0	58	33	4	0	1	0	0	.490	.534	.647	1.182
9	Cubs	17	9/13/2017	CHC	vs	NYM	W 17-5	38	16	3	1	2	17	11	0	9	0	0	51	27	6	2	0	1	0	.421	.551	.711	1.262
10	Twins	17	9/2/2017	MIN	vs	KCR	W 17-0	36	14	2	2	3	17	9	0	4	0	0	46	29	7	0	1	0	1	.389	.500	.806	1.306
11	Cubs	17	8/30/2017	CHC	vs	PIT	W 17-3	45	20	4	0	4	16	1	1	9	2	0	47	36	8	0	0	0	0	.444	.468	.800	1.268
12	Cubs	17	8/26/2017	CHC	@	PHI	W 17-2	41	14	3	0	6	17	5	1	9	0	0	47	35	9	0	0	0	0	.341	.426	.854	1.279
13	Rangers	17	8/19/2017	TEX	vs	CWS	W 17-7	42	20	4	0	4	16	7	1	6	2	0	50	36	8	0	0	0	2	.476	.560	.857	1.417
14	Rockies	17	8/16/2017	COL	vs	ATL	W 17-2	42	18	6	0	3	17	7	0	11	0	0	49	33	9	0	0	0	0	.429	.510	.786	1.296
15	Astros	17	5/31/2017	HOU	@	MIN	W 17-6	44	19	2	0	6	16	7	0	3	1	0	52	39	8	0	1	1	0	.432	.500	.886	1.386
16	Blue Jays	17	5/29/2017	TOR	vs	CIN	W 17-2	46	23	5	0	3	16	7	1	1	0	0	54	37	8	0	0	0	1	.500	.574	.804	1.378
17	Red Sox	17	5/7/2017	BOS	@	MIN	W 17-6	42	16	6	1	5	17	9	1	5	1	0	52	39	12	0	0	2	1	.381	.500	.929	1.429
18	Phillies	17	4/8/2017	PHI	vs	WSH	W 17-3	37	15	3	3	2	16	5	0	10	1	0	45	30	8	0	3	0	1	.405	.444	.811	1.255
19	Rockies	16	9/16/2017	COL	vs	SDP	W 16-0	37	17	2	0	3	15	6	1	4	1	0	45	28	5	1	0	0	3	.459	.545	.757	1.302
20	Twins	16	9/12/2017	MIN	vs	SDP	W 16-0	42	18	2	1	7	16	1	1	6	0	0	44	43	10	0	0	0	0	.429	.455	1.024	1.478
21	Yankees	16	9/10/2017	NYY	@	TEX	W 16-7	44	18	5	1	4	15	3	2	2	0	0	50	37	10	0	1	0	1	.409	.460	.841	1.301
22	Orioles	16	8/25/2017	BAL	@	BOS	W 16-3	48	21	1	1	2	14	2	0	8	1	0	52	30	4	0	2	0	0	.438	.442	.625	1.067
23	Astros	16	8/4/2017	HOU	vs	TOR	W 16-7	40	18	5	0	5	16	7	0	1	0	0	47	38	10	0	0	0	2	.450	.532	.950	1.482
24	Cubs	16	8/1/2017	CHC	vs	ARI	W 16-4	40	17	2	0	5	16	4	0	6	0	0	45	34	7	0	1	0	1	.425	.467	.850	1.317
25	Royals	16	7/26/2017	KCR	@	DET	W 16-2	47	22	2	0	1	16	4	3	7	2	1	55	27	3	0	1	0	0	.468	.527	.574	1.102