Since 1980, the New York Yankees have the most wins by a team, with 4,085 wins.

Interpreted as:

MLB team most regular-season wins since 1980

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	4,085	3,136	.566	7,224	247,477	36,162	65,632	12,113	1,026	8,825	34,457	26,785	2,361	47,050	4,476	1,679	280,161	106,272	21,964	1,360	2,178	1,696	6,002	.265	.340	.429	.769
2	Dodgers	3,954	3,276	.547	7,232	245,563	31,954	63,069	11,286	1,238	7,193	30,275	23,924	2,101	48,381	4,947	2,055	276,534	98,410	19,717	3,003	1,943	2,184	5,183	.257	.326	.401	.726
3	Red Sox	3,869	3,358	.535	7,228	250,618	36,049	68,058	14,382	1,265	7,754	34,247	25,436	2,367	46,923	3,420	1,501	282,044	108,232	23,401	1,422	2,201	1,878	6,110	.272	.342	.432	.773
4	Braves	3,865	3,352	.536	7,220	245,651	32,655	63,314	11,978	1,176	7,595	30,990	24,108	1,953	49,117	4,191	1,985	276,380	100,429	20,749	2,813	1,855	2,124	5,477	.258	.327	.409	.736
5	Cardinals	3,840	3,378	.532	7,223	245,304	32,590	63,961	12,120	1,441	6,520	30,813	24,151	2,259	47,388	5,544	2,227	276,609	98,523	20,081	2,846	2,049	2,231	5,378	.261	.330	.402	.732
6	Astros	3,748	3,484	.518	7,233	246,032	32,180	63,405	12,239	1,387	6,893	30,475	23,635	2,352	48,245	5,312	2,206	276,678	99,097	20,519	2,635	2,024	2,051	5,344	.258	.326	.403	.729
7	Giants	3,696	3,535	.511	7,232	245,864	31,595	62,632	11,808	1,532	6,741	29,878	23,861	2,069	49,201	4,134	2,004	276,685	97,727	20,081	2,909	1,982	2,491	5,330	.255	.323	.397	.721
8	Blue Jays	3,689	3,538	.510	7,230	248,010	33,929	64,688	13,044	1,389	8,114	32,243	23,115	2,390	47,597	4,453	1,816	276,864	104,852	22,547	1,303	2,046	1,340	5,615	.261	.327	.423	.750
9	Athletics	3,682	3,547	.509	7,229	245,699	33,329	62,144	11,902	1,067	7,743	31,571	25,786	2,229	49,135	4,620	1,784	277,375	99,409	20,712	1,546	2,115	1,292	5,632	.253	.327	.405	.731
10	Guardians	3,667	3,550	.508	7,219	247,083	34,009	65,143	12,597	1,240	7,297	32,237	24,281	2,286	46,403	5,044	2,037	277,682	102,111	21,134	1,779	2,253	1,568	5,667	.264	.332	.413	.746
11	Mets	3,642	3,578	.504	7,222	244,897	31,481	62,153	11,771	1,229	6,979	29,845	23,672	2,304	48,835	4,834	1,892	275,525	97,319	19,979	2,668	1,984	2,224	5,235	.254	.323	.397	.720
12	Phillies	3,630	3,597	.502	7,230	246,724	32,377	63,094	12,162	1,574	7,071	30,668	24,522	2,232	50,709	4,946	1,641	277,883	99,617	20,807	2,487	1,918	2,233	5,112	.256	.326	.404	.730
13	Angels	3,627	3,604	.502	7,231	246,662	32,977	64,055	11,647	1,192	7,356	31,194	23,037	2,217	46,779	4,528	2,137	275,962	100,154	20,195	2,049	1,997	1,641	5,676	.260	.326	.406	.732
14	Brewers	3,603	3,624	.499	7,229	246,176	32,982	63,433	12,215	1,387	7,406	31,311	23,570	2,440	49,872	5,059	2,089	276,514	100,640	21,008	2,316	2,012	1,735	5,389	.258	.326	.409	.735
15	White Sox	3,545	3,676	.491	7,227	246,151	32,935	63,993	11,679	1,318	7,552	31,344	22,310	2,259	46,926	4,568	2,043	274,796	100,964	20,549	2,011	2,065	1,419	5,571	.260	.325	.410	.735
16	Rangers	3,545	3,679	.491	7,228	248,208	34,533	65,374	12,389	1,295	8,049	32,755	23,056	2,163	48,903	4,437	1,932	277,184	104,500	21,733	1,673	2,084	1,459	5,449	.263	.329	.421	.750
17	Cubs	3,535	3,681	.490	7,223	246,434	32,047	63,017	11,963	1,439	7,474	30,364	22,879	2,181	50,806	4,310	1,899	276,016	100,280	20,876	2,660	1,862	2,016	5,196	.256	.322	.407	.729
18	Reds	3,534	3,695	.489	7,234	245,257	31,905	62,381	12,015	1,276	7,356	30,174	23,902	2,320	51,407	5,576	2,148	276,187	99,016	20,647	2,789	1,919	2,041	5,121	.254	.324	.404	.728
19	Nationals	3,531	3,693	.489	7,227	244,716	30,842	62,441	12,462	1,453	6,471	29,099	22,687	2,254	48,557	5,712	2,236	274,468	97,222	20,386	2,910	1,901	2,210	5,245	.255	.322	.397	.719
20	Twins	3,505	3,723	.485	7,230	247,998	33,019	65,278	12,736	1,503	6,773	31,210	22,644	2,268	46,602	4,004	1,898	276,397	101,339	21,012	1,401	2,086	1,487	5,924	.263	.328	.409	.737
21	Mariners	3,502	3,725	.485	7,229	246,729	32,335	63,347	11,894	1,143	7,541	30,737	23,468	2,330	48,563	4,778	2,026	276,234	100,150	20,578	1,753	1,954	1,598	5,370	.257	.325	.406	.731
22	Padres	3,498	3,737	.483	7,237	244,988	30,328	61,671	11,239	1,369	6,260	28,609	23,580	1,863	50,046	5,086	2,082	275,050	94,428	18,868	2,701	1,918	2,071	5,355	.252	.320	.385	.705
23	Orioles	3,474	3,746	.481	7,224	247,162	32,989	63,985	12,017	992	8,149	31,439	23,440	2,170	46,860	3,664	1,627	276,300	102,433	21,158	1,519	2,009	1,387	5,829	.259	.326	.414	.740
24	Tigers	3,469	3,756	.480	7,226	247,470	33,289	64,405	11,933	1,636	7,679	31,659	23,561	2,024	50,086	3,751	1,902	276,666	102,647	21,248	1,556	2,055	1,405	5,413	.260	.327	.415	.742
25	Royals	3,370	3,850	.467	7,221	247,329	31,683	65,008	12,414	1,751	6,032	29,991	20,435	2,161	44,700	5,503	2,136	273,785	99,020	20,197	1,746	2,114	1,367	5,548	.263	.322	.400	.722