Since 2021, the Colorado Rockies have the fewest wins by a team, with 269 wins.

Interpreted as:

MLB team with least regular-season wins since 2021

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Rockies	269	419	.391	688	23,216	2,974	5,728	1,200	135	707	2,851	1,960	244	6,242	300	106	25,684	9,319	2,042	92	172	66	518	.247	.310	.401	.711
2	Nationals	279	411	.404	690	23,108	2,861	5,780	1,131	90	645	2,716	2,021	312	5,229	525	170	25,708	9,026	1,866	112	155	72	548	.250	.317	.391	.708
3	Athletics	286	403	.415	689	22,860	2,719	5,249	1,049	80	754	2,590	2,091	301	6,043	431	105	25,506	8,720	1,883	89	165	49	475	.230	.301	.381	.682
4	White Sox	288	401	.418	689	23,170	2,769	5,585	1,089	54	672	2,647	1,883	256	5,837	323	92	25,526	8,798	1,815	78	139	47	528	.241	.304	.380	.683
5	Pirates	289	401	.419	690	22,938	2,687	5,328	1,032	118	630	2,557	2,195	237	6,156	418	132	25,632	8,486	1,780	95	167	68	429	.232	.304	.370	.674
6	Marlins	297	391	.432	688	23,129	2,678	5,591	1,040	93	653	2,550	1,842	251	6,027	477	136	25,465	8,776	1,786	89	154	75	513	.242	.303	.379	.682
7	Angels	303	385	.440	688	23,019	2,873	5,453	1,009	100	831	2,743	2,011	294	6,266	380	140	25,542	9,155	1,940	78	140	99	458	.237	.305	.398	.702
8	Royals	306	385	.443	691	23,150	2,887	5,693	1,092	152	662	2,771	1,833	239	5,400	562	159	25,542	9,075	1,906	97	223	55	411	.246	.305	.392	.697
9	Rangers	317	373	.459	690	23,309	3,038	5,647	1,049	81	816	2,904	2,082	227	5,856	444	124	25,819	9,306	1,946	44	157	61	419	.242	.309	.399	.708
10	Diamondbacks	321	369	.465	690	23,207	3,221	5,690	1,200	143	750	3,056	2,340	273	5,638	465	111	26,171	9,426	2,093	140	211	72	460	.245	.319	.406	.725
11	Reds	324	366	.470	690	23,038	3,114	5,552	1,120	100	792	2,975	2,216	393	6,194	538	163	25,891	9,248	2,012	87	157	47	464	.241	.316	.401	.718
12	Tigers	334	356	.484	690	23,104	2,825	5,476	1,019	147	668	2,714	2,001	220	6,229	313	99	25,551	8,793	1,834	48	178	41	445	.237	.302	.381	.682
13	Cubs	335	355	.486	690	23,137	3,155	5,634	1,085	126	796	3,008	2,288	334	6,136	530	148	26,025	9,359	2,007	96	170	66	465	.244	.318	.405	.723
14	Twins	341	348	.495	689	23,240	3,109	5,677	1,181	87	857	2,962	2,225	348	6,053	267	82	26,028	9,603	2,125	39	176	59	513	.244	.317	.413	.731
15	Orioles	342	345	.498	687	23,182	3,073	5,656	1,163	107	830	2,948	2,039	275	5,916	381	110	25,727	9,523	2,100	54	177	53	416	.244	.310	.411	.721
16	Red Sox	351	340	.508	691	23,664	3,294	6,078	1,411	90	802	3,142	2,118	286	6,088	393	120	26,287	10,075	2,303	43	176	100	479	.257	.323	.426	.749
17	Cardinals	360	330	.522	690	23,291	3,066	5,797	1,155	77	809	2,939	2,216	310	5,535	405	114	26,080	9,533	2,041	79	184	78	458	.249	.320	.409	.729
18	Guardians	364	324	.529	688	23,043	2,954	5,631	1,115	102	684	2,798	1,975	302	5,172	562	136	25,591	9,002	1,901	78	193	130	461	.244	.310	.391	.701
19	Blue Jays	366	322	.532	688	23,353	3,194	5,986	1,233	71	836	3,067	2,185	269	5,292	345	114	26,011	9,869	2,140	44	160	66	529	.256	.325	.423	.748
20	Padres	368	320	.535	688	23,114	3,131	5,750	1,142	76	765	2,991	2,398	250	5,310	449	130	26,055	9,339	1,983	112	181	104	510	.249	.324	.404	.728
21	Mets	369	321	.535	690	22,980	3,096	5,657	1,076	92	820	2,961	2,194	430	5,639	371	90	25,844	9,377	1,988	84	156	78	493	.246	.321	.408	.730
22	Giants	371	319	.538	690	23,115	3,079	5,517	1,114	91	817	2,946	2,349	304	6,230	279	77	26,023	9,264	2,022	75	180	95	481	.239	.315	.401	.716
23	Mariners	375	313	.545	688	22,914	3,018	5,300	1,026	57	847	2,895	2,414	410	6,461	448	122	25,943	8,981	1,930	43	162	55	435	.231	.314	.392	.706
24	Phillies	378	311	.549	689	23,340	3,254	5,882	1,155	112	863	3,123	2,251	263	5,945	508	111	26,115	9,850	2,130	83	178	101	466	.252	.323	.422	.745
25	Rays	383	305	.557	688	23,150	3,137	5,624	1,168	103	770	2,978	2,220	310	6,183	568	183	25,866	9,308	2,041	29	157	62	396	.243	.316	.402	.718