Since 1980, the New York Yankees have the most wins by a team, with 4,011 wins.

Interpreted as:

MLB team with most regular-season wins since 1980

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	4,011	3,084	.565	7,098	243,222	35,515	64,579	11,921	1,011	8,611	33,832	26,290	2,324	45,906	4,369	1,651	275,324	104,355	21,543	1,353	2,135	1,656	5,921	.266	.340	.429	.769
2	Dodgers	3,885	3,219	.547	7,106	241,293	31,322	61,996	11,089	1,224	7,007	29,670	23,477	2,057	47,332	4,886	2,036	271,718	96,554	19,320	2,991	1,900	2,155	5,101	.257	.326	.400	.726
3	Braves	3,806	3,284	.537	7,093	241,321	32,072	62,249	11,786	1,160	7,445	30,424	23,654	1,911	48,043	4,131	1,965	271,509	98,690	20,391	2,800	1,823	2,111	5,400	.258	.327	.409	.736
4	Red Sox	3,798	3,304	.535	7,103	246,336	35,443	66,968	14,130	1,246	7,610	33,670	25,052	2,310	45,844	3,324	1,470	277,278	106,420	22,986	1,411	2,169	1,863	6,028	.272	.342	.432	.774
5	Cardinals	3,780	3,313	.533	7,098	241,133	32,070	62,956	11,927	1,433	6,407	30,320	23,804	2,185	46,348	5,482	2,208	271,963	96,970	19,767	2,824	2,017	2,222	5,293	.261	.330	.402	.733
6	Astros	3,678	3,427	.518	7,106	241,698	31,630	62,312	12,037	1,379	6,741	29,949	23,271	2,295	47,221	5,248	2,185	271,884	97,330	20,157	2,625	1,995	2,041	5,245	.258	.326	.403	.729
7	Giants	3,638	3,468	.512	7,107	241,716	31,070	61,660	11,630	1,509	6,607	29,377	23,435	2,014	48,136	4,088	1,988	271,997	96,129	19,746	2,893	1,939	2,479	5,248	.255	.324	.398	.721
8	Athletics	3,626	3,478	.510	7,104	241,419	32,756	61,067	11,662	1,057	7,570	31,015	25,399	2,191	48,001	4,557	1,761	272,630	97,553	20,289	1,531	2,090	1,280	5,549	.253	.327	.404	.731
9	Blue Jays	3,611	3,489	.509	7,103	243,667	33,254	63,504	12,809	1,377	7,948	31,590	22,704	2,341	46,753	4,400	1,799	271,999	102,911	22,134	1,274	2,013	1,320	5,505	.261	.327	.422	.749
10	Guardians	3,600	3,491	.508	7,093	242,949	33,515	64,222	12,402	1,224	7,171	31,755	23,904	2,239	45,339	4,943	2,011	273,068	100,585	20,797	1,756	2,220	1,543	5,609	.264	.333	.414	.747
11	Mets	3,582	3,513	.505	7,097	240,676	30,889	61,103	11,576	1,219	6,795	29,266	23,248	2,238	47,782	4,709	1,879	270,760	95,502	19,590	2,654	1,944	2,202	5,149	.254	.323	.397	.720
12	Angels	3,569	3,534	.502	7,103	242,405	32,429	63,088	11,478	1,178	7,177	30,667	22,628	2,143	45,476	4,459	2,115	271,184	98,453	19,833	2,039	1,969	1,623	5,599	.260	.326	.406	.733
13	Phillies	3,554	3,546	.501	7,103	242,398	31,766	61,975	11,947	1,556	6,896	30,072	24,132	2,185	49,649	4,855	1,618	273,072	97,722	20,399	2,473	1,884	2,220	5,044	.256	.326	.403	.729
14	Brewers	3,525	3,577	.496	7,104	241,890	32,350	62,303	12,000	1,373	7,270	30,715	23,134	2,383	48,900	4,941	2,047	271,679	98,859	20,643	2,300	1,972	1,726	5,313	.258	.326	.409	.735
15	White Sox	3,495	3,600	.493	7,101	241,939	32,415	62,996	11,480	1,309	7,413	30,841	21,938	2,219	45,868	4,511	2,029	270,126	99,333	20,202	1,993	2,037	1,412	5,482	.260	.325	.411	.736
16	Rangers	3,482	3,616	.491	7,102	243,928	33,968	64,371	12,192	1,284	7,905	32,213	22,654	2,110	47,859	4,331	1,908	272,409	102,846	21,381	1,664	2,053	1,442	5,379	.264	.329	.422	.751
17	Nationals	3,482	3,617	.490	7,102	240,522	30,317	61,422	12,256	1,431	6,348	28,595	22,357	2,211	47,504	5,620	2,199	269,858	95,584	20,035	2,899	1,869	2,199	5,159	.255	.322	.397	.720
18	Reds	3,469	3,635	.488	7,109	241,052	31,366	61,349	11,820	1,256	7,226	29,667	23,511	2,285	50,314	5,513	2,130	271,509	97,359	20,302	2,779	1,882	2,029	5,034	.255	.324	.404	.728
19	Cubs	3,465	3,626	.489	7,098	242,244	31,476	61,986	11,761	1,419	7,306	29,811	22,471	2,146	49,829	4,195	1,872	271,334	98,503	20,486	2,655	1,818	2,003	5,140	.256	.322	.407	.729
20	Twins	3,451	3,651	.486	7,104	243,763	32,483	64,267	12,550	1,487	6,612	30,703	22,251	2,201	45,517	3,910	1,872	271,667	99,627	20,649	1,392	2,060	1,478	5,841	.264	.328	.409	.737
21	Mariners	3,433	3,667	.484	7,102	242,414	31,748	62,293	11,706	1,136	7,353	30,174	23,077	2,263	47,416	4,657	2,001	271,414	98,330	20,195	1,735	1,925	1,572	5,288	.257	.325	.406	.731
22	Padres	3,431	3,677	.483	7,110	240,705	29,766	60,597	11,038	1,354	6,137	28,074	23,182	1,814	49,124	5,012	2,061	270,246	92,754	18,529	2,662	1,883	2,057	5,278	.252	.320	.385	.705
23	Orioles	3,412	3,680	.481	7,096	242,847	32,442	62,958	11,808	977	8,000	30,918	23,052	2,112	45,702	3,561	1,596	271,503	100,720	20,785	1,515	1,977	1,374	5,753	.259	.326	.415	.741
24	Tigers	3,404	3,694	.480	7,099	243,197	32,710	63,361	11,735	1,606	7,528	31,109	23,175	1,974	48,944	3,705	1,888	271,915	100,892	20,869	1,555	2,014	1,396	5,342	.261	.327	.415	.742
25	Royals	3,309	3,786	.466	7,096	243,119	31,159	63,956	12,185	1,733	5,899	29,480	20,102	2,105	43,861	5,423	2,107	269,135	97,304	19,817	1,723	2,086	1,353	5,468	.263	.322	.400	.722