Since 1900, the New York Yankees have the most wins by a team, with 10,803 wins.

Interpreted as:

MLB team with the most regular-season wins since 1900

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	10,803	8,166	.570	19,057	649,526	92,617	172,445	28,632	5,493	17,317	86,058	68,572	4,929	94,813	11,649	2,800	735,905	264,014	51,442	9,595	3,283	2,831	10,679	.265	.339	.406	.745
2	Giants	10,352	9,062	.533	19,507	663,684	87,303	173,726	28,384	5,646	14,970	80,343	61,871	5,096	96,566	12,554	3,144	744,973	258,312	49,000	11,307	3,015	4,017	10,179	.262	.328	.389	.717
3	Dodgers	10,329	9,085	.532	19,509	663,272	85,026	172,970	28,193	5,721	13,665	78,364	62,231	4,434	97,370	13,401	3,550	745,229	253,600	47,579	12,232	3,060	3,733	9,938	.261	.327	.382	.709
4	Cardinals	10,129	9,283	.522	19,518	667,084	86,850	177,311	30,601	6,409	12,581	79,854	60,689	4,787	95,531	13,486	3,615	747,090	258,473	49,591	11,390	3,140	3,775	10,133	.266	.330	.387	.717
5	Red Sox	9,977	9,286	.518	19,346	662,135	90,353	176,687	33,112	5,598	14,599	83,789	66,797	4,803	95,541	9,630	2,548	747,669	264,792	53,309	10,595	3,339	2,997	11,546	.267	.337	.400	.737
6	Guardians	9,877	9,387	.513	19,355	659,683	87,509	174,642	31,139	5,497	13,915	80,874	62,616	4,834	94,569	11,910	3,387	741,949	258,520	50,551	11,462	3,354	2,545	10,524	.265	.331	.392	.723
7	Cubs	9,797	9,627	.504	19,531	664,053	85,161	172,424	29,614	5,717	14,282	78,242	60,890	4,740	101,825	11,947	3,070	745,001	256,318	49,613	12,414	2,904	3,518	9,962	.260	.325	.386	.711
8	Pirates	9,787	9,621	.504	19,504	666,208	84,790	175,668	29,477	7,426	11,826	77,937	58,213	4,783	96,523	12,651	3,268	744,119	255,475	48,729	11,800	3,115	3,698	10,050	.264	.326	.383	.709
9	Tigers	9,705	9,582	.503	19,380	660,898	89,014	174,620	29,580	6,295	14,576	81,967	65,538	4,444	96,689	11,291	2,936	744,996	260,518	50,451	11,009	3,107	2,447	10,714	.264	.333	.394	.727
10	Reds	9,677	9,755	.498	19,527	663,168	84,233	172,315	29,388	6,013	13,741	77,747	60,086	4,839	99,540	13,969	3,405	743,142	254,952	49,142	12,013	3,036	3,646	9,715	.260	.324	.384	.709
11	White Sox	9,608	9,642	.499	19,353	655,278	84,060	170,141	28,200	5,550	12,281	77,268	62,085	5,247	92,043	13,621	3,482	738,197	246,284	46,031	12,368	3,219	2,461	10,516	.260	.327	.376	.703
12	Braves	9,516	9,868	.491	19,495	662,918	82,409	170,762	28,125	4,853	14,194	76,102	60,161	4,427	97,191	10,514	3,066	742,378	251,175	47,172	11,994	2,878	3,655	10,376	.258	.322	.379	.701
13	Athletics	9,351	9,881	.486	19,319	654,832	85,277	168,562	29,191	5,332	14,139	78,581	64,493	4,731	98,989	12,103	3,206	737,841	250,834	48,662	10,682	3,103	2,269	10,615	.257	.327	.383	.710
14	Twins	9,283	9,975	.482	19,367	660,668	85,160	173,263	29,750	6,332	12,013	78,402	62,353	5,156	94,445	12,013	3,079	741,530	251,716	48,095	10,189	3,164	2,663	10,969	.262	.329	.381	.710
15	Orioles	9,135	10,111	.475	19,356	657,466	83,572	169,646	29,317	4,911	14,428	77,268	63,275	4,474	98,299	10,544	2,779	738,846	252,069	48,656	10,531	3,100	2,575	10,840	.258	.326	.383	.709
16	Phillies	9,099	10,291	.469	19,467	662,577	82,939	171,322	29,868	5,447	13,589	76,416	61,110	4,652	102,219	11,567	2,913	742,596	252,851	48,904	11,245	3,012	3,739	9,861	.259	.324	.382	.706
17	Angels	5,038	5,140	.495	10,181	345,415	44,042	88,370	15,274	1,810	9,207	41,441	32,302	2,820	62,693	6,044	3,099	386,843	134,885	26,291	3,537	2,769	2,483	7,874	.256	.322	.391	.713
18	Astros	5,031	4,986	.502	10,022	340,109	42,740	86,701	15,903	2,172	8,417	40,223	32,342	2,897	62,895	7,147	3,132	382,091	132,199	26,492	4,030	2,713	3,144	7,404	.255	.323	.389	.711
19	Mets	4,844	5,164	.484	10,016	338,876	41,331	84,684	15,127	1,817	8,578	38,917	32,393	2,857	64,921	5,883	2,734	380,730	129,179	25,522	3,987	2,617	3,137	7,457	.250	.318	.381	.700
20	Rangers	4,842	5,323	.476	10,171	347,209	45,765	89,561	15,962	1,891	10,194	43,243	32,881	2,698	65,143	5,937	2,846	388,581	139,887	28,047	2,963	2,830	2,250	7,795	.258	.325	.403	.727
21	Brewers	4,329	4,553	.487	8,886	301,630	39,498	77,232	14,396	1,755	8,702	37,420	29,027	2,708	58,880	5,978	2,731	338,940	121,244	24,853	3,161	2,414	2,158	6,609	.256	.325	.402	.726
22	Nationals	4,283	4,596	.482	8,883	300,433	37,203	76,228	14,703	1,788	7,598	34,965	28,248	2,623	57,153	6,546	2,773	337,466	117,301	24,089	3,878	2,284	2,880	6,501	.254	.321	.390	.711
23	Royals	4,233	4,643	.477	8,878	303,669	38,827	79,744	14,906	2,288	7,001	36,644	25,994	2,457	52,104	7,088	2,894	337,156	120,229	24,195	2,368	2,668	1,867	6,779	.263	.323	.396	.719
24	Padres	4,154	4,732	.467	8,888	300,467	36,042	74,939	13,259	1,759	7,257	33,891	28,609	2,124	59,431	6,002	2,603	337,158	113,487	22,275	3,710	2,248	2,686	6,498	.249	.317	.378	.695
25	Blue Jays	3,782	3,810	.498	7,595	260,225	35,110	67,678	13,526	1,491	8,254	33,303	24,127	2,423	48,942	4,571	1,963	290,399	108,948	23,271	1,499	2,125	1,400	5,924	.260	.326	.419	.745