Since 1900, the New York Yankees have the most wins by a team, with 10,826 wins.

Interpreted as:

MLB team with the most regular-season wins since 1900

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	10,826	8,184	.569	19,098	650,894	92,793	172,774	28,694	5,500	17,369	86,225	68,734	4,939	95,173	11,676	2,810	737,460	264,575	51,563	9,598	3,295	2,847	10,709	.265	.339	.406	.745
2	Giants	10,372	9,083	.533	19,548	664,998	87,445	174,019	28,438	5,655	15,003	80,476	62,023	5,118	96,898	12,573	3,151	746,485	258,776	49,096	11,319	3,027	4,020	10,214	.262	.328	.389	.717
3	Dodgers	10,353	9,102	.532	19,550	664,678	85,246	173,325	28,261	5,727	13,725	78,575	62,382	4,451	97,698	13,414	3,555	746,816	254,215	47,713	12,232	3,073	3,744	9,969	.261	.327	.382	.709
4	Cardinals	10,152	9,302	.522	19,560	668,502	87,041	177,658	30,661	6,412	12,625	80,037	60,799	4,812	95,857	13,502	3,620	748,660	259,018	49,698	11,395	3,152	3,779	10,159	.266	.330	.387	.717
5	Red Sox	9,997	9,307	.518	19,387	663,526	90,544	177,027	33,193	5,605	14,649	83,971	66,934	4,824	95,920	9,656	2,557	749,231	265,377	53,447	10,599	3,348	3,003	11,573	.267	.337	.400	.737
6	Guardians	9,892	9,411	.512	19,394	660,959	87,636	174,921	31,197	5,502	13,948	80,997	62,731	4,845	94,907	11,940	3,395	743,364	258,966	50,647	11,467	3,362	2,551	10,551	.265	.331	.392	.723
7	Cubs	9,821	9,643	.505	19,571	665,444	85,370	172,789	29,687	5,724	14,343	78,446	61,010	4,750	102,131	11,997	3,077	746,537	256,953	49,754	12,416	2,917	3,524	9,978	.260	.325	.386	.711
8	Pirates	9,808	9,642	.504	19,546	667,602	84,959	176,017	29,542	7,433	11,856	78,099	58,337	4,797	96,890	12,676	3,280	745,667	255,993	48,831	11,804	3,127	3,703	10,085	.264	.326	.383	.709
9	Tigers	9,729	9,599	.503	19,421	662,268	89,194	174,962	29,655	6,307	14,626	82,143	65,656	4,464	97,037	11,302	2,940	746,521	261,109	50,588	11,010	3,123	2,450	10,733	.264	.333	.394	.727
10	Reds	9,700	9,772	.498	19,567	664,507	84,418	172,659	29,454	6,021	13,786	77,921	60,207	4,848	99,881	13,986	3,414	744,628	255,513	49,261	12,016	3,050	3,649	9,744	.260	.324	.385	.709
11	White Sox	9,622	9,668	.499	19,393	656,598	84,198	170,444	28,268	5,556	12,314	77,396	62,216	5,255	92,392	13,644	3,492	739,676	246,766	46,138	12,375	3,232	2,464	10,542	.260	.327	.376	.703
12	Braves	9,532	9,891	.491	19,534	664,237	82,573	171,088	28,177	4,855	14,234	76,261	60,310	4,437	97,528	10,527	3,071	743,870	251,677	47,266	11,996	2,890	3,660	10,405	.258	.322	.379	.701
13	Athletics	9,364	9,911	.486	19,362	656,280	85,441	168,907	29,256	5,336	14,186	78,740	64,647	4,745	99,374	12,131	3,212	739,465	251,393	48,778	10,684	3,109	2,272	10,654	.257	.327	.383	.710
14	Twins	9,299	9,999	.482	19,407	662,029	85,334	173,593	29,810	6,335	12,067	78,571	62,473	5,183	94,778	12,028	3,084	743,048	252,274	48,212	10,191	3,172	2,665	10,996	.262	.329	.381	.710
15	Orioles	9,157	10,131	.475	19,398	658,909	83,771	170,016	29,393	4,915	14,479	77,455	63,394	4,493	98,673	10,580	2,789	740,442	252,676	48,787	10,533	3,113	2,580	10,867	.258	.326	.383	.709
16	Phillies	9,124	10,308	.470	19,509	663,990	83,127	171,677	29,937	5,452	13,633	76,596	61,244	4,672	102,545	11,601	2,920	744,177	253,417	49,022	11,249	3,022	3,742	9,884	.259	.324	.382	.706
17	Angels	5,062	5,157	.495	10,222	346,809	44,243	88,708	15,334	1,814	9,273	41,633	32,428	2,848	63,090	6,062	3,111	388,404	135,489	26,421	3,541	2,778	2,489	7,898	.256	.322	.391	.713
18	Astros	5,059	4,999	.503	10,063	341,488	42,916	87,061	15,956	2,174	8,472	40,391	32,446	2,919	63,205	7,172	3,142	383,608	132,781	26,602	4,031	2,724	3,146	7,441	.255	.323	.389	.711
19	Mets	4,864	5,185	.484	10,057	340,249	41,494	85,008	15,185	1,819	8,635	39,079	32,530	2,882	65,259	5,915	2,739	382,280	129,736	25,639	3,989	2,630	3,145	7,488	.250	.318	.381	.700
20	Rangers	4,859	5,346	.476	10,211	348,573	45,924	89,863	16,020	1,895	10,232	43,392	33,012	2,716	65,492	5,979	2,855	390,111	140,369	28,147	2,966	2,844	2,258	7,813	.258	.324	.403	.727
21	Brewers	4,355	4,567	.488	8,926	302,986	39,702	77,588	14,459	1,759	8,744	37,614	29,169	2,723	59,201	6,021	2,746	340,477	121,797	24,962	3,169	2,430	2,162	6,628	.256	.325	.402	.727
22	Nationals	4,300	4,618	.482	8,922	301,761	37,386	76,562	14,779	1,793	7,640	35,143	28,357	2,642	57,434	6,574	2,791	338,941	117,847	24,212	3,886	2,295	2,890	6,525	.254	.321	.391	.712
23	Royals	4,247	4,669	.476	8,918	305,010	38,952	80,073	14,972	2,295	7,030	36,766	26,079	2,471	52,372	7,114	2,909	338,613	120,725	24,297	2,377	2,676	1,873	6,801	.263	.323	.396	.719
24	Padres	4,172	4,756	.467	8,930	301,867	36,191	75,260	13,322	1,765	7,291	34,034	28,734	2,136	59,734	6,025	2,610	338,715	113,985	22,378	3,719	2,259	2,690	6,524	.249	.317	.378	.694
25	Blue Jays	3,807	3,826	.499	7,636	261,616	35,309	68,043	13,591	1,494	8,299	33,492	24,267	2,441	49,190	4,588	1,969	291,968	109,519	23,384	1,508	2,136	1,408	5,955	.260	.326	.419	.745