Between the 2010 and 2021 seasons, the Los Angeles Dodgers had the most wins by a team, with 1,068 wins.

Interpreted as:

MLB teams with most regular-season wins 2010 to 2021

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	1,068	774	.580	1,842	62,214	8,346	15,785	3,148	285	2,091	7,936	6,339	719	14,449	945	359	70,330	25,776	5,524	595	463	482	1,347	.254	.328	.414	.742
2	Yankees	1,046	796	.568	1,842	62,518	8,935	15,913	2,958	249	2,484	8,535	6,483	695	14,418	1,003	297	70,478	26,821	5,691	259	523	272	1,408	.255	.329	.429	.758
3	Cardinals	1,019	821	.554	1,840	62,231	8,321	15,981	3,179	279	1,923	7,917	5,962	773	13,991	800	359	70,044	25,487	5,381	592	486	454	1,445	.257	.327	.410	.737
4	Rays	1,000	843	.543	1,843	62,356	8,159	15,446	3,127	367	2,069	7,772	6,270	772	15,464	1,190	473	70,174	25,514	5,563	272	504	297	1,274	.248	.322	.409	.731
5	Red Sox	988	854	.536	1,842	64,112	9,223	17,094	3,781	287	2,170	8,763	6,174	610	14,188	977	307	71,627	27,959	6,238	217	514	423	1,459	.267	.334	.436	.770
6	Indians	970	870	.527	1,840	62,306	8,247	15,724	3,291	267	1,970	7,852	6,137	637	13,993	1,191	362	69,956	25,459	5,528	359	517	299	1,351	.252	.323	.409	.732
7	Nationals	970	871	.527	1,841	62,305	8,298	15,922	3,142	289	2,075	7,894	6,030	657	14,638	1,120	357	70,089	25,867	5,506	609	488	474	1,336	.256	.325	.415	.741
8	Braves	966	874	.525	1,840	62,422	8,046	15,727	3,131	266	1,918	7,676	6,084	596	14,756	882	354	70,123	25,144	5,315	605	416	496	1,350	.252	.322	.403	.725
9	Athletics	961	881	.522	1,842	62,500	8,278	15,404	3,205	304	2,053	7,861	6,138	652	14,171	935	300	69,995	25,376	5,562	216	489	240	1,385	.246	.318	.406	.724
10	Giants	957	885	.520	1,842	62,889	7,713	15,939	3,181	404	1,641	7,337	5,530	530	13,973	838	365	69,980	24,851	5,226	533	498	450	1,423	.253	.317	.395	.712
11	Brewers	948	895	.514	1,843	62,189	8,103	15,566	3,063	313	2,176	7,724	5,854	755	15,400	1,292	404	69,774	25,783	5,552	567	409	388	1,371	.250	.320	.415	.735
12	Angels	925	917	.502	1,842	62,511	8,216	15,793	3,064	275	2,043	7,827	5,604	661	13,555	1,051	398	69,602	25,536	5,382	339	487	367	1,465	.253	.318	.409	.727
13	Rangers	925	918	.502	1,843	62,729	8,528	16,093	3,061	297	2,129	8,087	5,515	727	14,185	1,284	477	69,844	26,135	5,487	370	503	299	1,328	.257	.321	.417	.738
14	Cubs	922	920	.501	1,843	62,277	8,032	15,416	3,117	331	2,063	7,638	5,965	830	15,650	790	382	69,967	25,384	5,511	495	400	425	1,337	.248	.320	.408	.727
15	Blue Jays	917	925	.498	1,842	62,583	8,575	15,691	3,238	219	2,492	8,194	5,932	563	14,340	909	322	69,801	26,843	5,949	268	455	224	1,414	.251	.319	.429	.748
16	Astros	913	929	.496	1,842	62,627	8,256	15,903	3,223	263	2,109	7,853	5,720	631	14,487	1,089	427	69,820	25,979	5,595	368	474	270	1,439	.254	.320	.415	.735
17	Phillies	897	945	.487	1,842	62,571	7,815	15,473	3,019	357	1,888	7,448	5,655	665	14,615	1,004	296	69,831	24,870	5,264	538	402	456	1,268	.247	.315	.397	.712
18	Mets	896	946	.486	1,842	62,367	7,750	15,412	3,099	291	1,923	7,435	5,912	738	14,639	906	354	69,949	24,862	5,313	506	426	453	1,341	.247	.318	.399	.716
19	Reds	889	953	.483	1,842	62,351	8,022	15,631	3,021	285	2,090	7,663	5,894	764	14,870	1,081	439	70,112	25,492	5,396	647	456	429	1,297	.251	.321	.409	.730
20	Tigers	882	955	.480	1,837	63,046	8,149	16,551	3,221	393	1,889	7,811	5,459	533	14,502	758	329	69,806	26,225	5,503	276	492	364	1,487	.263	.324	.416	.740
21	Mariners	875	967	.475	1,842	62,307	7,506	15,080	2,842	246	1,978	7,164	5,516	613	15,038	1,038	411	69,155	24,348	5,066	304	415	269	1,251	.242	.308	.391	.699
22	Twins	874	968	.474	1,842	63,016	8,338	15,991	3,286	313	2,009	7,942	5,896	581	14,470	845	341	70,238	25,930	5,608	277	468	299	1,307	.254	.321	.411	.733
23	Pirates	872	968	.474	1,841	62,244	7,536	15,506	3,081	376	1,667	7,191	5,521	724	14,603	951	463	69,491	24,340	5,124	573	429	411	1,331	.249	.316	.391	.707
24	White Sox	871	970	.473	1,841	62,662	7,892	15,951	2,940	302	1,985	7,547	5,059	750	14,699	994	454	69,257	25,450	5,227	350	436	231	1,403	.255	.316	.406	.722
25	Diamondbacks	870	972	.472	1,842	63,002	8,216	15,845	3,306	458	1,927	7,823	5,925	576	15,292	1,065	388	70,447	25,848	5,691	488	456	457	1,301	.251	.319	.410	.730