Since 2002, the New York Yankees have the most wins by a team, with 2,150 wins.

Interpreted as:

MLB teams with the most regular-season wins since 2002

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	2,150	1,553	.581	3,704	126,391	18,796	32,947	6,213	456	5,074	18,004	13,760	1,484	27,536	2,207	679	143,220	55,294	11,743	549	1,036	702	2,995	.261	.338	.437	.775
2	Dodgers	2,116	1,588	.571	3,704	125,854	17,160	32,453	6,394	642	4,105	16,385	12,664	1,406	27,208	2,171	777	142,060	52,446	11,141	1,146	990	991	2,759	.258	.330	.417	.747
3	Cardinals	2,035	1,667	.550	3,702	125,919	17,204	32,919	6,509	540	3,989	16,386	12,149	1,493	26,254	1,757	741	141,822	52,475	11,038	1,234	1,027	1,026	2,895	.261	.331	.417	.748
4	Red Sox	2,018	1,688	.545	3,706	128,717	18,945	34,609	7,730	588	4,378	18,040	13,049	1,365	27,675	2,026	640	144,670	56,649	12,696	425	1,114	878	2,951	.269	.340	.440	.780
5	Braves	2,006	1,693	.542	3,700	126,320	17,152	32,687	6,574	559	4,201	16,399	12,365	1,213	28,282	1,766	687	142,019	52,982	11,334	1,203	918	971	2,843	.259	.329	.419	.748
6	Angels	1,917	1,787	.518	3,704	126,233	16,971	32,642	6,221	597	3,972	16,140	11,121	1,330	26,093	2,484	961	140,436	51,973	10,790	727	1,025	802	2,855	.259	.323	.412	.734
7	Phillies	1,915	1,788	.517	3,703	126,574	17,035	32,198	6,434	729	4,174	16,258	12,482	1,424	28,598	2,342	618	142,439	52,612	11,337	1,064	895	1,041	2,567	.254	.326	.416	.742
8	Astros	1,911	1,791	.516	3,703	125,837	16,759	32,293	6,462	562	4,177	15,988	11,727	1,361	27,044	2,129	820	140,906	52,410	11,201	1,017	964	711	2,927	.257	.324	.416	.741
9	Giants	1,909	1,791	.516	3,701	125,745	15,893	31,893	6,416	769	3,451	15,103	11,636	1,203	26,758	1,674	683	140,781	50,200	10,636	1,180	1,017	1,101	2,904	.254	.320	.399	.720
10	Guardians	1,905	1,794	.515	3,699	125,846	16,957	32,216	6,756	567	3,932	16,159	12,173	1,455	27,088	2,253	802	141,266	51,902	11,255	737	1,055	713	2,788	.256	.326	.412	.739
11	Rays	1,873	1,830	.506	3,703	125,725	16,568	31,732	6,378	738	3,998	15,775	12,034	1,485	29,400	2,855	1,017	140,820	51,580	11,114	565	1,011	591	2,506	.252	.323	.410	.733
12	Athletics	1,870	1,835	.505	3,705	125,882	16,466	31,221	6,430	537	3,989	15,695	12,549	1,299	27,389	1,810	578	141,192	50,692	10,956	479	983	522	2,903	.248	.320	.403	.723
13	Twins	1,868	1,837	.504	3,705	126,957	17,093	32,885	6,616	682	3,884	16,232	11,814	1,304	27,230	1,862	755	141,741	52,517	11,182	642	1,024	681	2,872	.259	.326	.414	.740
14	Brewers	1,864	1,841	.503	3,705	125,096	16,479	31,415	6,309	620	4,248	15,736	12,178	1,536	30,016	2,584	838	140,806	51,708	11,177	1,110	886	835	2,799	.251	.323	.413	.736
15	Cubs	1,863	1,839	.503	3,703	125,950	16,630	31,907	6,470	665	4,169	15,839	11,973	1,457	29,260	1,897	768	141,384	52,214	11,304	1,120	884	831	2,720	.253	.323	.415	.738
16	Blue Jays	1,856	1,846	.501	3,702	126,467	17,386	32,518	6,844	520	4,474	16,608	11,931	1,312	26,829	1,700	635	141,216	53,824	11,838	500	1,006	516	2,979	.257	.325	.426	.751
17	Mets	1,847	1,856	.499	3,703	125,531	16,213	31,628	6,252	620	3,911	15,489	11,960	1,515	27,522	2,277	720	141,097	50,853	10,783	1,164	927	952	2,751	.252	.322	.405	.727
18	Rangers	1,833	1,873	.495	3,706	127,014	17,824	32,900	6,481	605	4,552	16,983	11,397	1,354	28,043	2,291	800	141,439	54,247	11,638	655	1,019	619	2,599	.259	.324	.427	.751
19	Mariners	1,809	1,894	.489	3,703	126,116	15,861	31,600	5,944	515	3,841	15,095	11,312	1,391	28,217	2,280	834	140,401	50,097	10,300	665	917	680	2,650	.251	.317	.397	.714
20	Diamondbacks	1,786	1,918	.482	3,704	126,220	16,735	31,959	6,672	903	3,898	15,967	12,267	1,210	28,563	2,146	750	141,825	52,131	11,473	1,092	1,036	899	2,665	.253	.323	.413	.736
21	Padres	1,777	1,928	.480	3,705	124,907	15,447	30,841	5,966	665	3,546	14,682	12,053	1,161	28,649	2,240	791	140,206	48,775	10,177	1,125	960	772	2,668	.247	.317	.390	.707
22	Nationals	1,776	1,927	.480	3,703	125,150	16,093	31,839	6,423	600	3,714	15,317	11,931	1,366	27,536	2,331	872	140,725	50,604	10,737	1,328	950	920	2,811	.254	.324	.404	.728
23	White Sox	1,759	1,946	.475	3,705	125,969	16,355	32,110	6,036	503	4,226	15,677	10,601	1,418	27,645	2,002	890	139,659	51,830	10,765	760	911	491	2,852	.255	.318	.411	.729
24	Reds	1,752	1,953	.473	3,706	125,381	16,406	31,349	6,207	548	4,239	15,670	12,230	1,577	29,674	2,347	873	141,344	51,369	10,994	1,272	884	827	2,591	.250	.322	.410	.732
25	Tigers	1,746	1,954	.472	3,700	126,760	16,440	32,924	6,295	853	3,833	15,736	10,808	1,148	28,247	1,607	725	140,369	52,424	10,981	655	998	628	2,847	.260	.321	.414	.735