Justin Verlander has appeared in the most career games by an active starting pitcher, with 539 games.

Interpreted as:

most career regular-season games by an active starting pitcher

	NAME	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Justin Verlander J. Verlander	539	262	152	.633	539	3.32	3,471	26	9	0	3483.1	2,960	1,284	1,389	364	977	117	0	27	14,239	97	8.97	2.52	3.55	0.94	24.4	6.9	1.13	.279	3.59	7.65
2	Max Scherzer M. Scherzer	460	215	112	.657	460	3.17	3,401	12	5	0	2872.0	2,347	1,012	1,085	336	752	110	0	20	11,606	79	10.66	2.36	4.52	1.05	29.3	6.5	1.08	.287	3.40	7.35
3	Clayton Kershaw C. Kershaw	437	216	94	.697	437	2.51	2,992	25	15	0	2777.1	2,122	775	850	232	689	44	0	27	10,957	105	9.70	2.23	4.34	0.75	27.3	6.3	1.01	.270	2.75	6.88
4	Charlie Morton C. Morton	394	142	129	.524	394	4.07	2,106	3	2	0	2179.1	2,057	986	1,084	210	810	192	0	25	9,352	70	8.70	3.35	2.60	0.87	22.5	8.7	1.32	.306	4.48	8.49
5	Jose Quintana J. Quintana	344	108	105	.507	344	3.74	1,712	2	2	0	1982.2	1,939	824	891	200	601	53	0	22	8,317	72	7.77	2.73	2.85	0.91	20.6	7.2	1.28	.302	4.04	8.80
6	Patrick Corbin P. Corbin	339	106	136	.438	339	4.55	1,754	7	2	0	1937.0	2,076	979	1,051	272	588	49	0	22	8,343	62	8.15	2.73	2.98	1.26	21.0	7.0	1.38	.318	4.88	9.65
7	Gerrit Cole G. Cole	317	153	80	.657	317	3.18	2,251	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	7.49
8	Sonny Gray S. Gray	315	116	97	.545	315	3.52	1,810	7	5	0	1816.0	1,559	711	779	176	593	56	0	5	7,508	105	8.97	2.94	3.05	0.87	24.1	7.9	1.19	.284	3.86	7.73
9	Wade Miley W. Miley	312	107	99	.519	312	4.08	1,365	3	2	0	1741.2	1,766	789	846	195	606	46	0	10	7,448	58	7.05	3.13	2.25	1.01	18.3	8.1	1.36	.300	4.37	9.13
10	Kevin Gausman K. Gausman	307	104	105	.498	307	3.87	1,785	3	1	0	1756.2	1,709	755	807	218	496	37	0	7	7,366	60	9.15	2.54	3.60	1.12	24.2	6.7	1.26	.309	4.13	8.76
11	Chris Sale C. Sale	307	139	84	.623	307	3.04	2,416	16	3	0	1952.1	1,600	659	711	201	443	124	0	12	7,863	44	11.14	2.04	5.45	0.93	30.7	5.6	1.05	.299	3.28	7.38
12	Nathan Eovaldi N. Eovaldi	288	93	84	.525	288	3.97	1,406	5	3	0	1617.1	1,596	713	756	181	443	50	0	17	6,789	47	7.82	2.47	3.17	1.01	20.7	6.5	1.26	.300	4.21	8.88
13	Kyle Hendricks K. Hendricks	286	102	87	.540	286	3.75	1,312	6	4	0	1651.0	1,579	687	739	198	382	68	0	19	6,826	12	7.15	2.08	3.43	1.08	19.2	5.6	1.19	.284	4.03	8.61
14	Yu Darvish Y. Darvish	282	110	88	.556	282	3.58	2,007	2	1	0	1706.0	1,394	678	712	217	544	77	0	8	7,009	79	10.59	2.87	3.69	1.14	28.6	7.8	1.14	.283	3.76	7.35
15	Aaron Nola A. Nola	277	105	86	.550	277	3.78	1,831	6	4	0	1671.0	1,482	701	739	210	437	55	0	16	6,855	18	9.86	2.35	4.19	1.13	26.7	6.4	1.15	.294	3.98	7.98
16	Zack Wheeler Z. Wheeler	276	111	73	.603	276	3.27	1,761	4	3	0	1685.2	1,440	612	664	157	482	71	0	14	6,914	40	9.40	2.57	3.65	0.84	25.5	7.0	1.14	.289	3.55	7.69
17	Michael Wacha M. Wacha	274	102	70	.593	274	3.78	1,308	2	2	0	1501.1	1,432	630	673	175	473	40	0	18	6,313	39	7.84	2.84	2.77	1.05	20.7	7.5	1.27	.291	4.03	8.58
18	Martín Pérez M. Pérez	273	88	88	.500	273	4.46	1,063	4	3	0	1517.0	1,649	752	826	178	549	46	0	7	6,587	39	6.31	3.26	1.94	1.06	16.1	8.3	1.45	.310	4.90	9.78
19	José Berríos J. Berríos	260	102	80	.560	260	4.02	1,431	5	1	0	1506.1	1,398	673	717	205	454	95	0	7	6,318	35	8.55	2.71	3.15	1.22	22.6	7.2	1.23	.289	4.28	8.35
20	Marcus Stroman M. Stroman	256	87	86	.503	256	3.75	1,197	4	2	0	1456.1	1,418	606	673	140	443	38	0	5	6,092	46	7.40	2.74	2.70	0.87	19.6	7.3	1.28	.299	4.16	8.76
21	Robbie Ray R. Ray	246	85	76	.528	246	3.88	1,652	1	1	0	1351.0	1,168	582	620	201	571	47	0	19	5,713	57	11.01	3.80	2.89	1.34	28.9	10.0	1.29	.298	4.13	7.78
22	Jacob deGrom J. deGrom	235	93	59	.612	235	2.49	1,766	4	2	0	1468.1	1,120	407	444	130	329	24	0	13	5,762	28	10.82	2.02	5.37	0.80	30.6	5.7	0.99	.282	2.72	6.86
23	Alex Cobb A. Cobb	233	78	76	.506	233	3.84	1,108	6	2	0	1327.2	1,307	566	620	140	383	47	0	15	5,577	51	7.51	2.60	2.89	0.95	19.9	6.9	1.27	.299	4.20	8.86
24	Luis Castillo L. Castillo	228	76	81	.484	228	3.56	1,410	1	0	0	1326.1	1,132	524	572	163	439	43	0	8	5,486	17	9.57	2.98	3.21	1.11	25.7	8.0	1.18	.282	3.88	7.68
25	Jon Gray J. Gray	223	72	70	.507	223	4.47	1,201	2	1	0	1209.1	1,187	601	640	155	396	51	0	10	5,141	44	8.94	2.95	3.03	1.15	23.4	7.7	1.31	.309	4.76	8.83