9 players were tied for their most home runs in a game, with 3 home runs. The first three are José Ramírez on April 4 and on June 8, 2023, Jose Altuve on September 5, 2023 and José Abreu on August 22, 2020.

Interpreted as:

most career home runs in a regular-season game player named jose

	NAME	HR	DATE	TM		OPP	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	José Ramírez J. Ramírez	3	4/4/2025	CLE	@	LAA	4	3	3	0	0	4	1	0	1	0	0	5	12	3	0	0	0	0
2	Jose Altuve J. Altuve	3	9/5/2023	HOU	@	TEX	5	3	3	0	0	3	0	0	1	0	0	5	12	3	0	0	0	0
3	José Ramírez J. Ramírez	3	6/8/2023	CLE	vs	BOS	5	3	3	0	0	5	0	0	1	0	0	5	12	3	0	0	0	0
4	José Abreu J. Abreu	3	8/22/2020	CWS	@	CHC	4	3	4	0	0	4	1	0	0	0	0	5	13	3	0	0	0	0
5	Jose Bautista J. Bautista	3	5/15/2011	TOR	@	MIN	5	3	3	0	0	4	0	0	0	0	0	5	12	3	0	0	0	0
6	Jose Lopez J. Lopez	3	9/22/2010	SEA	@	TOR	4	3	3	0	0	4	0	0	0	0	0	4	12	3	0	0	0	0
7	Jose Reyes J. Reyes	3	8/15/2006	NYM	@	PHI	3	3	3	0	0	4	1	0	0	0	0	4	12	3	0	0	0	0
8	Jose Valentin J. Valentin	3	7/30/2003	CWS	@	KCR	4	3	3	0	0	5	2	0	1	0	0	6	12	3	0	0	0	0
9	Jose Ortiz J. Ortiz	3	8/17/2001	COL	vs	FLA	5	3	3	0	0	4	0	0	0	0	0	5	12	3	0	0	0	0
10	Jose Valentin J. Valentin	3	4/3/1998	MIL	@	FLA	3	3	3	0	0	5	1	0	0	1	0	4	12	3	0	0	0	0
11	Jose Canseco J. Canseco	3	6/13/1994	TEX	vs	SEA	6	3	5	0	0	8	0	0	1	0	0	6	14	3	0	0	0	0
12	Jose Canseco J. Canseco	3	7/3/1988	OAK	@	TOR	7	3	3	0	0	6	1	0	2	0	0	8	12	3	0	0	0	0
13	Jose Altuve J. Altuve	2	5/27/2025	HOU	vs	ATH	4	3	4	0	0	3	0	0	0	0	0	4	10	2	0	0	0	0
14	Jose Altuve J. Altuve	2	5/22/2025	HOU	vs	SEA	4	2	2	0	0	4	0	0	0	0	0	5	8	2	0	1	0	0
15	José Ramírez J. Ramírez	2	7/29/2024	CLE	@	DET	4	3	3	1	0	3	0	0	0	0	0	4	10	3	0	0	0	0
16	Jose Iglesias J. Iglesias	2	7/12/2024	NYM	vs	COL	4	2	2	0	0	2	0	0	1	0	0	4	8	2	0	0	0	0
17	Jose Siri J. Siri	2	6/28/2024	TBR	vs	WSH	3	2	2	0	0	2	1	0	0	0	0	4	8	2	0	0	0	0
18	Jose Siri J. Siri	2	5/30/2024	TBR	vs	OAK	5	2	2	0	0	2	0	0	1	0	0	5	8	2	0	0	0	0
19	José Ramírez J. Ramírez	2	5/24/2024	CLE	@	LAA	4	2	2	0	0	4	1	0	0	0	0	5	8	2	0	0	0	0
20	Jose Trevino J. Trevino	2	5/12/2024	NYY	@	TBR	4	2	2	0	0	3	0	0	0	0	0	4	8	2	0	0	0	0
21	Jose Altuve J. Altuve	2	4/14/2024	HOU	vs	TEX	5	2	3	0	0	2	0	0	0	1	0	5	9	2	0	0	0	0
22	José Abreu J. Abreu	2	9/6/2023	HOU	@	TEX	5	2	3	1	0	7	0	0	0	0	0	5	10	3	0	0	0	0
23	Jose Altuve J. Altuve	2	9/4/2023	HOU	@	TEX	6	3	4	0	0	2	0	0	0	0	0	6	10	2	0	0	0	0
24	Jose Siri J. Siri	2	8/9/2023	TBR	vs	STL	4	2	2	0	0	3	0	0	1	0	0	4	8	2	0	0	0	0
25	José Ramírez J. Ramírez	2	7/30/2023	CLE	@	CWS	4	2	2	0	0	3	1	0	1	0	0	5	8	2	0	0	0	0