most career home runs while batting first in the lineup

17 players went deep 4 times. The first three are Lou Gehrig on June 3, 1932, Chuck Klein on July 10, 1936 and Pat Seerey on July 18, 1948.

Interpreted as:

most career home runs in a game while batting by a player first in the lineup

	NAME	HR	AVG	DATE	TM		OPP	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Lou Gehrig L. Gehrig	4	.667	6/3/1932	NYY	@	PHA	6	4	4	0	0	6	0	0	0	0	0	6	16	4	0
2	Chuck Klein C. Klein	4	.800	7/10/1936	PHN	@	PIT	5	4	4	0	0	6	0	0	0	0	0	5	16	4	0			0
3	Pat Seerey P. Seerey	4	.667	7/18/1948	CWS	@	PHA	6	4	4	0	0	7	1	0	1	0	0	7	16	4	0			0
4	Gil Hodges G. Hodges	4	.833	8/31/1950	BKN	vs	BSN	6	5	5	0	0	9	0	0	0	0	0	6	17	4	0		0	0
5	Joe Adcock J. Adcock	4	1.000	7/31/1954	MIL	@	BKN	5	5	5	1	0	7	0	0	0	0	0	5	18	5	0	0	0	0
6	Rocky Colavito R. Colavito	4	1.000	6/10/1959	CLE	@	BAL	4	5	4	0	0	6	1	0	0	0	0	5	16	4	0	0	0	0
7	Willie Mays W. Mays	4	.800	4/30/1961	SFG	@	MIL	5	4	4	0	0	8	0	0	0	0	0	5	16	4	0	0	0	0
8	Mike Schmidt M. Schmidt	4	.833	4/17/1976	PHI	@	CHC	6	4	5	0	0	8	0	0	0	0	0	6	17	4	0	0	0	0
9	Bob Horner B. Horner	4	.800	7/6/1986	ATL	vs	MON	5	4	4	0	0	6	0	0	0	0	0	5	16	4	0	0	0	0
10	Mark Whiten M. Whiten	4	.800	9/7/1993	STL	@	CIN	5	4	4	0	0	12	0	0	0	0	0	5	16	4	0	0	0	0
11	Mike Cameron M. Cameron	4	.800	5/2/2002	SEA	@	CWS	5	4	4	0	0	4	0	1	0	0	0	6	16	4	0	0	0	0
12	Shawn Green S. Green	4	1.000	5/23/2002	LAD	@	MIL	6	6	6	1	0	7	0	0	0	0	0	6	19	5	0	0	0	0
13	Carlos Delgado C. Delgado	4	1.000	9/25/2003	TOR	vs	TBD	4	4	4	0	0	6	0	0	0	0	0	4	16	4	0	0	0	0
14	Josh Hamilton J. Hamilton	4	1.000	5/8/2012	TEX	@	BAL	5	4	5	1	0	8	0	0	0	0	0	5	18	5	0	0	0	0
15	Scooter Gennett S. Gennett	4	1.000	6/6/2017	CIN	vs	STL	5	4	5	0	0	10	0	0	0	0	0	5	17	4	0	0	0	0
16	J.D. Martinez	4	.800	9/4/2017	ARI	@	LAD	5	4	4	0	0	6	0	0	1	0	0	5	16	4	0	0	0	0
17	Eugenio Suárez E. Suárez	4	1.000	4/26/2025	AZ	vs	ATL	4	4	4	0	0	5	0	0	0	0	0	4	16	4	0	0	0	0
18	Ken Williams K. Williams	3	.750	4/22/1922	SLA	vs	CWS	4	3	3	0	0	6	0	0	0	0	0	4	12	3	0
19	Butch Henline B. Henline	3	.600	9/15/1922	PHN	vs	SLN	5	3	3	0	0	6	0	0	1	0	0	5	12	3	0
20	Cy Williams C. Williams	3	.600	5/11/1923	PHN	vs	SLN	5	4	3	0	0	7	1	0	0	0	0	6	12	3	0
21	High Pockets Kelly H. Pockets Kelly	3	1.000	9/17/1923	NYG	@	CHC	5	4	5	1	0	4	0	0	0	0	0	5	15	4	0
22	High Pockets Kelly H. Pockets Kelly	3	1.000	6/14/1924	NYG	vs	CIN	4	3	4	0	0	8	1	0	0	0	0	5	13	3	0
23	Joe Hauser J. Hauser	3	.800	8/2/1924	PHA	@	CLE	5	4	4	1	0	4	0	0	1	0	0	5	14	4	0
24	Ty Cobb T. Cobb	3	1.000	5/5/1925	DET	@	SLA	6	4	6	1	0	5	0	0	0	0	1	6	16	4	0
25	Mickey Cochrane M. Cochrane	3	.750	5/21/1925	PHA	@	SLA	4	3	3	0	0	3	0	0	1	0	0	4	12	3	0