Nolan Ryan has the most career losses in starts, with 291 games.

Interpreted as:

most career regular-season losses as a starting player

	NAME	L	GS	W	L%	G	W%	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	291	773	318	.478	773	.522	3.18	5,654	222	61	0	5326.0	3,880	1,884	2,151	314	2,748	156	0	75	22,310	275	9.55	4.64	2.06	0.53	25.3	12.3	1.24	.265	3.63	6.56
2	Phil Niekro P. Niekro	262	716	302	.465	716	.535	3.37	3,181	245	45	0	5149.2	4,815	1,928	2,227	465	1,703	116	0	73	21,585	207	5.56	2.98	1.87	0.81	14.7	7.9	1.27	.270	3.89	8.42
3	Don Sutton D. Sutton	253	756	321	.441	756	.559	3.27	3,545	178	58	0	5248.1	4,670	1,905	2,095	469	1,333	81	0	96	21,500	110	6.08	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.59	8.01
4	Gaylord Perry G. Perry	252	690	305	.452	690	.548	3.10	3,372	303	53	0	5156.2	4,762	1,778	2,045	382	1,314	101	0	144	21,140	150	5.89	2.29	2.57	0.67	16.0	6.2	1.18	.274	3.57	8.31
5	Walter Johnson W. Johnson	249	666	376	.398	666	.602	1.69	3,273	531	110	0	5552.0	4,610		1,766	90	1,295	191	0			144	5.31	2.10	2.53	0.15		5.8	1.06	.261	2.86	7.47
6	Bert Blyleven B. Blyleven	248	685	286	.464	685	.536	3.31	3,694	242	60	0	4957.1	4,614	1,823	2,021	428	1,316	155	0	67	20,429	114	6.71	2.39	2.81	0.78	18.1	6.4	1.20	.282	3.67	8.38
7	Steve Carlton S. Carlton	240	709	327	.423	709	.577	3.20	4,104	254	55	0	5165.1	4,616	1,835	2,096	405	1,814	53	0	145	21,457	177	7.15	3.16	2.26	0.71	19.1	8.5	1.24	.279	3.65	8.04
8	Robin Roberts R. Roberts	240	609	275	.466	609	.534	3.41	2,292	305	45	0	4567.1	4,467	1,733	1,915	498	872	54	0	63	18,724	32	4.52	1.72	2.63	0.98	12.2	4.7	1.17	.264	3.77	8.80
9	Eppa Rixey E. Rixey	239	554	247	.492	554	.508	3.15	1,244	289	37	0	4171.2	4,335	1,462	1,849	84	982	71	0		17,427	84	2.68	2.12	1.27	0.18	7.1	5.6	1.27	.283	3.99	9.35
10	Frank Tanana F. Tanana	236	616	236	.500	616	.500	3.67	2,734	143	34	0	4136.1	4,019	1,688	1,893	445	1,227	128	0	110	17,413	114	5.95	2.67	2.23	0.97	15.7	7.0	1.27	.278	4.12	8.74
11	Early Wynn E. Wynn	232	611	287	.447	611	.553	3.56	2,255	289	49	0	4398.2	4,135	1,742	1,981	330	1,713	62	0	32	18,704	50	4.61	3.50	1.32	0.68	12.1	9.2	1.33	.265	4.05	8.46
12	Tommy John T. John	228	700	284	.445	700	.555	3.35	2,191	162	46	0	4622.1	4,699	1,718	1,981	295	1,223	98	0	99	19,321	178	4.27	2.38	1.79	0.57	11.3	6.3	1.28	.284	3.86	9.15
13	Warren Spahn W. Spahn	227	665	358	.388	665	.612	3.08	2,501	382	63	0	5101.0	4,703	1,743	1,951	422	1,383	39	0	52	20,960	74	4.41	2.44	1.81	0.74	11.9	6.6	1.19	.258	3.44	8.30
14	Greg Maddux G. Maddux	226	740	355	.389	740	.611	3.15	3,366	109	35	0	5001.0	4,717	1,750	1,974	351	996	137	0	177	20,388	70	6.06	1.79	3.38	0.63	16.5	4.9	1.14	.281	3.55	8.49
15	Fergie Jenkins F. Jenkins	218	594	278	.440	594	.560	3.32	3,082	267	49	0	4358.2	4,021	1,608	1,786	463	951	83	0	101	17,815	61	6.36	1.96	3.24	0.96	17.3	5.3	1.14	.269	3.69	8.30
16	Bob Friend B. Friend	218	497	186	.540	497	.460	3.62	1,642	163	36	0	3378.2	3,560	1,359	1,562	273	822	42	0	102	14,262	48	4.37	2.19	2.00	0.73	11.5	5.8	1.30	.286	4.16	9.48
17	Jim Kaat J. Kaat	217	625	260	.455	625	.545	3.43	2,294	180	31	0	4137.2	4,203	1,579	1,850	366	955	115	0	77	17,336	116	4.99	2.08	2.40	0.80	13.2	5.5	1.25	.282	4.02	9.14
18	Red Ruffing R. Ruffing	212	538	264	.445	538	.555	3.82	1,869	335	45	0	4132.2	4,094	1,755	2,016	249	1,463	51	0		17,623	44	4.07	3.19	1.28	0.54	10.6	8.3	1.34	.275	4.39	8.92
19	Ted Lyons T. Lyons	210	484	245	.462	484	.538	3.60	1,010	356	27	0	3907.0	4,196	1,564	1,900	208	1,027	30	0		16,676	48	2.33	2.37	0.98	0.48	6.1	6.2	1.34	.277	4.38	9.67
20	Bobo Newsom B. Newsom	207	483	196	.514	483	.486	4.00	1,969	246	31	0	3524.2	3,544	1,566	1,797	189	1,598	51	0		15,438	50	5.03	4.08	1.23	0.48	12.8	10.4	1.46	.288	4.59	9.05
21	Jamie Moyer J. Moyer	206	638	262	.440	638	.560	4.27	2,353	33	10	0	3947.1	4,107	1,872	2,020	509	1,104	142	0	64	16,812	52	5.36	2.52	2.13	1.16	14.0	6.6	1.32	.283	4.61	9.36
22	Jerry Koosman J. Koosman	204	527	216	.486	527	.514	3.39	2,464	140	33	0	3681.2	3,495	1,388	1,558	285	1,145	67	0	112	15,342	82	6.02	2.80	2.15	0.70	16.1	7.5	1.26	.282	3.81	8.54
23	Tom Glavine T. Glavine	203	682	305	.400	682	.600	3.54	2,607	56	25	0	4413.1	4,298	1,734	1,900	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	8.76
24	Tom Seaver T. Seaver	203	647	310	.396	647	.604	2.86	3,634	231	61	0	4776.1	3,961	1,517	1,670	378	1,387	76	0	115	19,337	123	6.85	2.61	2.62	0.71	18.8	7.2	1.12	.258	3.15	7.46
25	Sad Sam Jones S. Sam Jones	200	488	213	.484	488	.516	3.80	1,122	250	36	0	3533.1	3,713	1,493	1,789	142	1,264	64	0		15,243	66	2.86	3.22	0.89	0.36	7.4	8.3	1.41	.282	4.56	9.46

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StatMuse has game-level data for pitcher losses and starts going back to the 1901 season.

Some of the information used here was obtained free of charge from Retrosheet.

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RBI

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AVG

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Team Pitching Leaders

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ERA

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Team Rankings

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4th

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25th

1,280

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2025 Division Standings

TEAM	W	L	PCT	GB
Mariners	90	72	.556
Astros	87	75	.537	3.0
Rangers	81	81	.500	9.0
Athletics	76	86	.469	14.0
Angels	72	90	.444	18.0

Schedule

DATE	MATCHUP			TIME (ET)
Thu 3/26	LAA	@	HOU	4:00 AM
Fri 3/27	LAA	@	HOU	4:00 AM
Sat 3/28	LAA	@	HOU	4:00 AM
Sun 3/29	LAA	@	HOU	4:00 AM
Mon 3/30	LAA	@	CHC	4:00 AM

Last Game

Astros

87 - 75

Final

Angels

72 - 90

Sun 28 Sep 2025

MLB 2025 Batting Leaders

HR Leaders

60

Raleigh

56

Schwarber

55

Ohtani

RBI Leaders

132

Schwarber

126

Alonso

125

Raleigh

Batting Average Leaders

.331

Judge

.311

Bichette

.311

Wilson

Hit Leaders

184

Witt

181

Bichette

181

Arraez

Run Leaders

146

Ohtani

137

Judge

120

Soto

OBP Leaders

.457

Judge

.399

Springer

.396

Soto

SLG Leaders

.688

Judge

.622

Ohtani

.589

Raleigh

SB Leaders

49

Caballero

44

Ramírez

44

Simpson

MLB 2025 Pitching Leaders

Win Leaders

19

Fried

18

Crochet

18

Rodón

Strikeout Leaders

255

Crochet

241

Skubal

224

Webb

ERA Leaders

1.97

Skenes

2.21

Skubal

2.43

Brown

WHIP Leaders

0.89

Skubal

0.92

deGrom

0.93

Woo

K/9 Leaders

11.52

Cease

11.18

Crochet

11.10

Skubal

K/BB Leaders

7.30

Skubal

5.54

Crochet

5.50

Woo

Walk Leaders

32

Littell

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Skubal

36

Woo

MLB Fantasy 2025

FanDuel Points Leaders

2,712.2

Ohtani

2,418.4

Judge

2,278.5

Soto

DraftKings Points Leaders

1,990.4

Ohtani

1,802

Judge

1,702

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MLB 2025 Betting

Best Record ATS

95-67

94-68

101-79

95-76

90-75

Worst Record ATS

65-96

75-99

76-94

81-98

74-88

75-87

MLB 2025 Standings

NL East	W	L	PCT	GB
Phillies - y	96	66	.593
Mets	83	79	.512	13.0
Marlins	79	83	.488	17.0
Braves	76	86	.469	20.0
Nationals	66	96	.407	30.0
NL Central	W	L	PCT	GB
Brewers - y	97	65	.599
Cubs - w	92	70	.568	5.0
Reds - w	83	79	.512	14.0
Cardinals	78	84	.481	19.0
Pirates	71	91	.438	26.0
NL West	W	L	PCT	GB
Dodgers - y	93	69	.574
Padres - w	90	72	.556	3.0
Giants	81	81	.500	12.0
Diamondbacks	80	82	.494	13.0
Rockies	43	119	.265	50.0

AL East	W	L	PCT	GB
Blue Jays - y	94	68	.580
Yankees - w	94	68	.580
Red Sox - w	89	73	.549	5.0
Rays	77	85	.475	17.0
Orioles	75	87	.463	19.0
AL Central	W	L	PCT	GB
Guardians - y	88	74	.543
Tigers - w	87	75	.537	1.0
Royals	82	80	.506	6.0
Twins	70	92	.432	18.0
White Sox	60	102	.370	28.0
AL West	W	L	PCT	GB
Mariners - y	90	72	.556
Astros	87	75	.537	3.0
Rangers	81	81	.500	9.0
Athletics	76	86	.469	14.0
Angels	72	90	.444	18.0

MLB 2025 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Tue 9/16	CIN	@	STL	6-2
Tue 9/16	ATL	@	WSH	9-4
Tue 9/16	ATH	@	BOS	4-5
Tue 9/16	TOR	@	TBR	1-2
Tue 9/16	SEA	@	KCR	5-7

Schedule

DATE	MATCHUP			TIME (ET)
Wed 3/25	NYY	@	SFG	8:05 PM
Thu 3/26	LAA	@	HOU	4:00 AM
Thu 3/26	WSH	@	CHC	4:00 AM
Thu 3/26	CWS	@	MIL	2:10 PM
Thu 3/26	MIN	@	BAL	3:05 PM

Nolan Ryan has the most career losses in starts, with 291 games.

Interpreted as:

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