The Chicago Cubs have the most games by a team, with 22,329 games.

Interpreted as:

most common regular-season matchup between two teams

	TEAM	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	22,329	.513	11,372	10,796	764,133	102,817	200,108	33,799	7,362	15,286	88,402	68,649	5,291	105,260	15,822	3,075	854,015	294,489	56,447	13,027	2,915	3,524	9,975	.262	.326	.385	.711
2	Braves	22,290	.504	11,148	10,988	763,155	99,624	198,192	32,143	6,302	15,083	86,666	67,596	5,075	100,366	14,104	3,070	851,399	288,188	53,528	12,686	2,887	3,659	10,400	.260	.323	.378	.701
3	Reds	21,914	.504	10,973	10,802	746,659	98,340	194,534	32,428	7,561	14,356	87,480	66,799	5,511	102,501	18,175	3,414	834,848	285,152	54,345	12,665	3,046	3,649	9,734	.261	.325	.382	.707
4	Pirates	21,874	.500	10,869	10,865	749,222	97,261	197,167	32,389	8,940	12,272	86,763	64,406	5,540	99,844	15,702	3,280	834,976	284,252	53,601	12,563	3,122	3,702	10,077	.263	.325	.379	.704
5	Giants	21,798	.535	11,583	10,052	743,896	100,766	195,638	31,386	7,042	15,609	90,234	68,403	5,690	99,804	16,533	3,150	832,686	287,935	54,037	11,672	3,025	4,020	10,204	.263	.329	.387	.716
6	Phillies	21,723	.474	10,252	11,356	743,284	96,461	193,541	33,458	6,682	14,222	86,680	67,831	5,426	105,552	14,982	2,920	831,479	283,029	54,362	11,919	3,019	3,742	9,876	.260	.326	.381	.706
7	Dodgers	21,715	.532	11,478	10,098	739,914	98,064	193,324	31,103	7,010	14,171	88,278	69,010	5,161	100,574	17,353	3,553	830,008	280,960	52,284	12,774	3,073	3,743	9,966	.261	.327	.380	.707
8	Cardinals	20,681	.513	10,545	10,005	707,411	92,537	187,977	31,868	7,052	12,887	84,593	64,269	5,219	98,377	15,024	3,619	792,024	272,610	51,807	11,977	3,148	3,778	10,153	.266	.330	.385	.715
9	Tigers	19,412	.503	9,724	9,595	661,965	89,141	174,875	29,640	6,302	14,611	82,092	65,632	4,457	96,964	11,299	2,939	746,179	260,952	50,553	11,009	3,116	2,450	10,729	.264	.333	.394	.727
10	Twins	19,397	.482	9,296	9,992	661,698	85,292	173,520	29,797	6,335	12,052	78,530	62,444	5,179	94,700	12,024	3,084	742,681	252,143	48,184	10,190	3,170	2,664	10,990	.262	.329	.381	.710
11	Orioles	19,388	.475	9,152	10,126	658,558	83,713	169,928	29,370	4,914	14,466	77,399	63,364	4,486	98,586	10,575	2,788	740,050	252,524	48,750	10,532	3,110	2,579	10,866	.258	.326	.383	.709
12	Guardians	19,385	.513	9,889	9,405	660,669	87,611	174,866	31,184	5,501	13,941	80,972	62,699	4,844	94,826	11,934	3,393	743,038	258,875	50,626	11,465	3,361	2,549	10,546	.265	.331	.392	.723
13	White Sox	19,384	.499	9,617	9,664	656,314	84,171	170,382	28,256	5,554	12,307	77,373	62,185	5,251	92,320	13,642	3,490	739,354	246,667	46,117	12,374	3,230	2,464	10,534	.260	.327	.376	.703
14	Red Sox	19,377	.518	9,994	9,300	663,182	90,490	176,937	33,171	5,603	14,635	83,921	66,904	4,820	95,829	9,648	2,554	748,848	265,219	53,409	10,598	3,344	3,002	11,567	.267	.337	.400	.737
15	Athletics	19,352	.486	9,360	9,905	655,957	85,409	168,837	29,251	5,334	14,178	78,709	64,615	4,742	99,288	12,126	3,210	739,104	251,290	48,763	10,683	3,107	2,272	10,644	.257	.327	.383	.710
16	Yankees	19,088	.570	10,821	8,179	650,551	92,746	172,690	28,679	5,498	17,354	86,182	68,692	4,936	95,073	11,671	2,810	737,068	264,427	51,531	9,597	3,292	2,842	10,704	.265	.339	.406	.745
17	Angels	10,213	.495	5,057	5,153	346,500	44,187	88,628	15,318	1,813	9,254	41,580	32,387	2,840	63,001	6,060	3,107	388,045	135,334	26,385	3,541	2,777	2,487	7,891	.256	.322	.391	.713
18	Rangers	10,201	.476	4,854	5,341	348,213	45,880	89,787	16,009	1,894	10,223	43,352	32,971	2,711	65,403	5,965	2,854	389,697	140,253	28,126	2,964	2,838	2,254	7,806	.258	.324	.403	.727
19	Astros	10,054	.503	5,052	4,997	341,200	42,887	86,996	15,950	2,174	8,460	40,365	32,423	2,915	63,131	7,168	3,139	383,291	132,674	26,584	4,031	2,722	3,145	7,438	.255	.323	.389	.711
20	Mets	10,047	.484	4,861	5,178	339,912	41,459	84,926	15,172	1,819	8,619	39,044	32,508	2,880	65,175	5,912	2,739	381,915	129,593	25,610	3,989	2,626	3,145	7,482	.250	.318	.381	.700
21	Padres	8,920	.467	4,167	4,751	301,540	36,158	75,185	13,307	1,765	7,281	34,001	28,699	2,134	59,672	6,023	2,608	338,350	113,865	22,353	3,718	2,259	2,689	6,520	.249	.317	.378	.694
22	Brewers	8,917	.488	4,348	4,565	302,666	39,632	77,486	14,442	1,759	8,734	37,549	29,133	2,721	59,147	6,014	2,740	340,109	121,648	24,935	3,167	2,422	2,161	6,622	.256	.325	.402	.726
23	Nationals	8,913	.482	4,296	4,613	301,434	37,330	76,468	14,759	1,792	7,627	35,087	28,324	2,641	57,356	6,563	2,787	338,571	117,692	24,178	3,882	2,290	2,883	6,522	.254	.321	.390	.711
24	Royals	8,908	.477	4,245	4,661	304,687	38,926	80,005	14,952	2,295	7,025	36,740	26,055	2,467	52,299	7,108	2,905	338,261	120,622	24,272	2,376	2,676	1,872	6,795	.263	.323	.396	.719
25	Blue Jays	7,626	.499	3,801	3,822	261,268	35,259	67,951	13,579	1,493	8,293	33,446	24,229	2,436	49,131	4,582	1,966	291,574	109,395	23,365	1,507	2,134	1,406	5,950	.260	.326	.419	.745