Since 1985, Vin Mazzaro and Mike Oquist are tied for allowing the most earned runs in a game, with 14 earned runs.

Interpreted as:

most earned runs by a player in one regular-season game since 1985

	NAME	ER	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Vin Mazzaro V. Mazzaro	14	5/16/2011	KCR	vs	CLE		0	54.00	2	0	0	0	2.1	11	14	1	3	0	0	0	21	1
2	Mike Oquist M. Oquist	14	8/3/1998	OAK	vs	NYY	L	1	25.20	3	0	0	0	5.0	16	14	4	3	0	0	0	32	0
3	Ben Lively B. Lively	13	8/1/2023	CIN	@	CHC	L	1	29.25	2	0	0	0	4.0	13	13	4	2	1	0	0	27	0
4	Scott Kazmir S. Kazmir	13	7/10/2010	LAA	@	OAK	L	1	23.40	2	0	0	0	5.0	11	13	3	3	1	0	1	30	2
5	Jason Marquis J. Marquis	13	6/21/2006	STL	@	CWS	L	1	23.40	3	0	0	0	5.0	14	13	4	1	0	0	0	30	0
6	David Wells D. Wells	13	8/20/1992	TOR	@	MIL	L	1	27.00	1	0	0	0	4.1	11	13	1	4	2	0	0	29	0
7	Bradley Blalock B. Blalock	12	5/10/2025	COL	vs	SDP	L	1	29.45	1	0	0	0	3.2	13	12	3	2	0	0	0	26	1
8	Jordan Yamamoto J. Yamamoto	12	9/9/2020	MIA	@	ATL		0	40.50	3	0	0	0	2.2	11	13	4	2	0	0	0	22	0
9	Masahiro Tanaka M. Tanaka	12	7/25/2019	NYY	@	BOS	L	1	32.40	4	0	0	0	3.1	12	12	2	3	0	0	0	25	0
10	A.J. Burnett	12	5/2/2012	PIT	@	STL	L	1	40.50	2	0	0	0	2.2	12	12	2	1	1	0	0	22	0
11	Randy Wolf R. Wolf	12	7/21/2010	MIL	@	PIT	L	1	19.06	4	0	0	0	5.2	13	12	2	2	0	0	0	31	0
12	Jason Marquis J. Marquis	12	7/18/2006	STL	vs	ATL	L	1	21.60	4	0	0	0	5.0	14	12	3	2	1	0	0	31	0
13	Shawn Chacon S. Chacon	12	6/7/2003	COL	vs	KCR	L	1	29.45	2	0	0	0	3.2	9	12	2	6	0	0	0	25	1
14	Jose Lima J. Lima	12	4/27/2000	HOU	vs	CHC	L	1	21.60	6	0	0	0	5.0	13	12	5	3	0	0	0	31	1
15	John Burkett J. Burkett	12	5/17/1999	TEX	vs	TBD	L	1	27.00	2	0	0	0	4.0	8	12	3	5	0	0	0	25	0
16	Tanner Houck T. Houck	11	4/14/2025	BOS	@	TBR	L	1	42.43	1	0	0	0	2.1	10	12	2	2	0	0	0	20	1
17	Braxton Garrett B. Garrett	11	5/3/2023	MIA	vs	ATL	L	1	22.85	3	0	0	0	4.1	14	11	4	2	0	0	0	28	0
18	Luis Cessa L. Cessa	11	4/16/2023	CIN	vs	PHI	L	1	33.00	0	0	0	0	3.0	14	11	1	3	1	0	0	27	1
19	Kohei Arihara K. Arihara	11	9/10/2022	TEX	vs	TOR	L	1	33.00	1	0	0	0	3.0	12	11	2	5	0	0	0	26	0
20	Ryan Weber R. Weber	11	6/13/2021	BOS	vs	TOR		0	17.47	7	0	0	0	5.2	13	11	4	2	0	0	0	30	0
21	Alec Bettinger A. Bettinger	11	5/2/2021	MIL	vs	LAD	L	1	24.75	0	0	0	0	4.0	11	11	2	2	1	0	0	26	1
22	Germán Márquez G. Márquez	11	7/15/2019	COL	vs	SFG	L	1	37.13	3	0	0	0	2.2	11	11	2	0	0	0	0	19	0
23	Austin Bibens-Dirkx A. Bibens-Dirkx	11	7/21/2018	TEX	vs	CLE		0	24.75	0	0	0	0	4.0	13	11	3	1	1	0	0	27	0
24	Jeff Locke J. Locke	11	7/3/2017	MIA	@	STL	L	1	37.13	2	0	0	0	2.2	11	11	0	4	0	0	1	23	0
25	Edinson Volquez E. Volquez	11	6/24/2016	KCR	vs	HOU	L	1	99.00	0	0	0	0	1.0	8	12	1	3	0	0	0	15	0