Andrew McCutchen has the most career games by an active player, with 2,190 games.

Interpreted as:

most regular-season games played by active MLB player

	NAME	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Andrew McCutchen A. McCutchen	2,190	8,090	1,261	2,209	440	50	326	1,121	1,144	94	1,825	220	89	9,405	3,727	816	3	74	70	139	.273	.367	.461	.827	1411	319.4	.358	127	296.8
2	Carlos Santana C. Santana	2,144	7,623	1,090	1,845	399	17	332	1,116	1,310	43	1,494	60	18	9,041	3,274	748	0	65	66	187	.242	.354	.429	.783	1244	189.9	.341	115	165
3	Freddie Freeman F. Freeman	2,091	7,778	1,335	2,342	529	32	352	1,273	1,036	109	1,684	98	31	8,987	3,991	913	0	64	140	166	.301	.388	.513	.901	1546	497.6	.383	143	464.8
4	Paul Goldschmidt P. Goldschmidt	1,997	7,375	1,248	2,135	460	24	369	1,218	1,073	51	1,928	174	35	8,555	3,750	853	0	56	119	170	.289	.381	.508	.889	1440	438.8	.378	139	394.6
5	Jose Altuve J. Altuve	1,888	7,556	1,189	2,304	441	31	239	842	619	76	1,076	321	94	8,327	3,524	711	26	50	47	201	.305	.361	.466	.828	1251	281.9	.356	129	286.9
6	Jason Heyward J. Heyward	1,824	6,174	879	1,575	306	41	186	730	706	62	1,238	125	43	6,982	2,521	533	6	34	27	104	.255	.336	.408	.744	866	54.1	.326	104	29.7
7	Manny Machado M. Machado	1,803	7,066	1,038	1,982	381	18	352	1,088	634	27	1,349	107	40	7,802	3,455	751	14	61	69	216	.280	.339	.489	.828	1146	230.5	.351	124	222.5
8	Nolan Arenado N. Arenado	1,746	6,657	976	1,887	398	34	349	1,168	570	42	1,074	29	23	7,352	3,400	781	5	78	79	198	.283	.340	.511	.851	1123	259	.358	117	154.5
9	Justin Turner J. Turner	1,716	5,634	803	1,600	349	9	199	825	584	136	995	46	13	6,421	2,564	557	5	62	18	145	.284	.362	.455	.817	956	200.3	.353	125	198.1
10	Bryce Harper B. Harper	1,710	6,147	1,114	1,725	382	24	345	1,010	1,070	49	1,580	148	50	7,338	3,190	751	13	59	133	136	.281	.388	.519	.907	1269	408.2	.383	142	370.4
11	DJ LeMahieu	1,653	6,079	891	1,758	277	39	126	660	571	31	1,029	93	49	6,765	2,491	442	37	47	24	188	.289	.351	.410	.761	884	89.6	.331	100	7.2
12	Giancarlo Stanton G. Stanton	1,649	6,025	907	1,551	305	11	429	1,103	776	53	1,963	42	15	6,893	3,165	745	0	39	88	153	.257	.345	.525	.871	1093	294.9	.368	135	288.9
13	Salvador Perez S. Perez	1,619	6,144	672	1,633	302	11	279	950	255	86	1,239	6	1	6,538	2,794	592	0	53	39	190	.266	.302	.455	.757	802	42.8	.322	102	13.3
14	Nick Castellanos N. Castellanos	1,611	6,129	785	1,679	389	42	239	880	416	53	1,540	40	22	6,648	2,869	670	0	50	19	135	.274	.323	.468	.791	906	121.4	.337	111	93.1
15	Xander Bogaerts X. Bogaerts	1,597	6,091	913	1,748	364	18	189	808	574	55	1,225	119	22	6,784	2,715	571	5	59	23	153	.287	.351	.446	.796	958	158.4	.343	115	121.6
16	Marcus Semien M. Semien	1,572	6,143	933	1,560	313	35	245	768	609	24	1,266	134	40	6,819	2,678	593	7	36	8	98	.254	.322	.436	.758	875	67.4	.327	108	70.8
17	Mike Trout M. Trout	1,561	5,665	1,143	1,683	313	55	389	981	1,000	101	1,533	214	38	6,824	3,273	757	0	58	122	71	.297	.408	.578	.986	1336	544.6	.413	168	546.9
18	Eugenio Suárez E. Suárez	1,540	5,484	781	1,358	247	15	295	883	606	95	1,691	33	19	6,253	2,520	557	9	59	15	124	.248	.330	.460	.789	861	119.1	.338	112	90.8
19	Marcell Ozuna M. Ozuna	1,535	5,792	794	1,573	268	21	286	914	561	25	1,413	29	14	6,411	2,741	575	1	32	19	148	.272	.337	.473	.810	923	170.3	.347	120	158.3
20	Christian Yelich C. Yelich	1,533	5,786	979	1,648	311	35	217	790	799	48	1,458	215	39	6,665	2,680	563	5	27	56	121	.285	.375	.463	.838	1036	252.8	.361	129	235.6
21	José Ramírez J. Ramírez	1,517	5,625	940	1,581	379	41	267	897	625	40	759	263	59	6,365	2,843	687	19	56	94	79	.281	.354	.505	.859	995	240.1	.361	131	232.4
22	Starling Marte S. Marte	1,480	5,584	859	1,592	282	55	158	651	332	165	1,225	358	100	6,126	2,458	495	22	23	18	117	.285	.342	.440	.782	835	119.9	.339	116	114.1
23	Francisco Lindor F. Lindor	1,444	5,719	941	1,570	317	26	262	808	549	72	1,044	198	47	6,432	2,725	605	31	61	36	104	.275	.342	.476	.819	939	173.3	.349	121	163.3
24	Mookie Betts M. Betts	1,444	5,738	1,118	1,680	378	40	280	864	707	50	882	193	39	6,552	2,978	698	4	53	34	75	.293	.372	.519	.891	1115	337.3	.378	139	308.9
25	George Springer G. Springer	1,371	5,270	911	1,379	237	23	271	743	642	79	1,262	109	40	6,027	2,475	531	2	34	12	115	.262	.349	.470	.818	896	182.9	.352	127	192.9