10 players were tied for the most games in 2005, with 162 games. The first three are Bobby Abreu, Jason Bay and Raul Ibanez.

Interpreted as:

most games played by a player in 2005

	NAME	G	SEASON	TM	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Bobby Abreu B. Abreu	162	2005	PHI	588	104	168	37	1	24	102	117	6	134	31	9	719	279	62	0	8	15	7	.286	.405	.474	.879	118	31.6	.379	128	25.7
2	Jason Bay J. Bay	162	2005	PIT	599	110	183	44	6	32	101	95	6	142	21	1	707	335	82	0	7	9	12	.306	.402	.559	.961	132	47.3	.407	150	44.1
3	Raul Ibanez R. Ibanez	162	2005	SEA	614	92	172	32	2	20	89	71	2	99	9	4	690	268	54	0	3	6	12	.280	.355	.436	.792	93	10.7	.345	115	12.5
4	Carlos Lee C. Lee	162	2005	MIL	618	85	164	41	0	32	114	57	2	87	13	4	688	301	73	0	11	7	8	.265	.324	.487	.811	92	9.7	.343	106	4.9
5	Hideki Matsui H. Matsui	162	2005	NYY	629	108	192	45	3	23	116	63	3	78	2	2	703	312	71	0	8	7	16	.305	.367	.496	.863	109	25	.369	128	24.3
6	Juan Pierre J. Pierre	162	2005	FLA	656	96	181	19	13	2	47	41	9	45	57	17	718	232	34	10	2	1	10	.276	.326	.354	.680	72	-13.9	.303	83	-15.4
7	Alex Rodriguez A. Rodriguez	162	2005	NYY	605	124	194	29	1	48	130	91	16	139	21	6	715	369	78	0	3	8	8	.321	.421	.610	1.031	151	65	.436	174	64.2
8	Ichiro Suzuki I. Suzuki	162	2005	SEA	679	111	206	21	12	15	68	48	4	66	33	8	739	296	48	2	6	23	5	.303	.350	.436	.786	92	3.4	.331	106	5.2
9	Mark Teixeira M. Teixeira	162	2005	TEX	644	112	194	41	3	43	144	72	11	124	4	0	730	370	87	0	3	5	18	.301	.379	.575	.954	135	47.5	.404	146	41.4
10	Miguel Tejada M. Tejada	162	2005	BAL	654	89	199	50	5	26	98	40	7	83	5	1	704	337	81	0	3	9	26	.304	.349	.515	.865	108	23.8	.367	127	23.1
11	Hank Blalock H. Blalock	161	2005	TEX	647	80	170	34	0	25	92	51	3	132	1	0	705	279	59	0	4	1	16	.263	.318	.431	.749	84	-0.2	.325	93	-6.1
12	Albert Pujols A. Pujols	161	2005	STL	591	129	195	38	2	41	117	97	9	65	16	2	700	360	81	0	3	27	19	.330	.430	.609	1.039	145	61.5	.432	167	59.1
13	Jose Reyes J. Reyes	161	2005	NYM	696	99	190	24	17	7	58	27	2	78	60	15	733	269	48	4	4	0	7	.273	.300	.386	.687	71	-16.4	.299	80	-18.9
14	Jeromy Burnitz J. Burnitz	160	2005	CHC	605	84	156	31	2	24	87	57	3	109	5	4	671	263	57	1	5	3	12	.258	.322	.435	.757	82	1.1	.328	94	-5.2
15	Eric Chavez E. Chavez	160	2005	OAK	625	92	168	40	1	27	101	58	2	129	6	0	694	291	68	0	9	4	9	.269	.329	.466	.794	91	8.1	.340	111	9
16	Adam Dunn A. Dunn	160	2005	CIN	543	107	134	35	2	40	101	114	12	168	4	2	671	293	77	0	2	14	6	.247	.387	.540	.927	117	36.7	.392	138	32
17	Brandon Inge B. Inge	160	2005	DET	616	75	161	31	9	16	72	63	3	140	7	6	694	258	56	6	6	1	14	.261	.330	.419	.749	84	0.5	.327	101	0.6
18	Andruw Jones A. Jones	160	2005	ATL	586	95	154	24	3	51	128	64	15	112	5	3	672	337	78	0	7	13	19	.263	.347	.575	.922	112	31.6	.383	134	28.5
19	Randy Winn R. Winn	160	2005	TOT	617	85	189	47	6	20	63	48	5	91	19	11	683	308	73	10	3	4	11	.306	.360	.499	.859	106	24.1	.368	128	23.8
20	David Wright D. Wright	160	2005	NYM	575	99	176	42	1	27	102	72	7	113	17	7	657	301	70	0	3	2	16	.306	.388	.523	.912	115	36.4	.393	141	34.2
21	Angel Berroa A. Berroa	159	2005	KCR	608	68	164	21	5	11	55	18	14	108	7	5	652	228	37	10	2	3	13	.270	.305	.375	.680	63	-15.2	.298	76	-19.1
22	Derek Jeter D. Jeter	159	2005	NYY	654	122	202	25	5	19	70	77	11	117	14	5	752	294	49	7	3	3	15	.309	.389	.450	.839	117	26.8	.369	128	26
23	David Ortiz D. Ortiz	159	2005	BOS	601	119	180	40	1	47	148	102	1	124	1	0	713	363	88	0	9	9	13	.300	.397	.604	1.001	140	54.5	.418	157	49.5
24	Michael Young M. Young	159	2005	TEX	668	114	221	40	5	24	91	58	3	91	5	2	732	343	69	0	3	0	20	.331	.385	.513	.899	126	38.2	.389	136	32.1
25	Miguel Cabrera M. Cabrera	158	2005	FLA	613	106	198	43	2	33	116	64	2	125	1	0	685	344	78	0	6	12	20	.323	.385	.561	.947	123	41.3	.399	146	39.9