Between the 2000 and 2012 seasons, Lance Berkman collected the most hits for the Astros, with 1,626 hits.

	NAME	H	G	AB	R	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Lance Berkman L. Berkman	1,626	1,558	5,467	998	373	26	322	1,075	1,028	61	1,100	77	41	6,606	3,017	721	1	49	134	122	.297	.411	.552	.963	1244	435	.407	147	393.7
2	Craig Biggio C. Biggio	1,192	1,151	4,487	724	279	17	139	469	374	132	780	68	20	5,068	1,922	435	44	31	15	78	.266	.338	.428	.766	650	23.6	.335	98	-14.9
3	Carlos Lee C. Lee	894	815	3,121	376	187	8	133	533	246	16	299	26	15	3,419	1,496	328	0	36	33	92	.286	.338	.479	.817	478	74.6	.350	115	64.1
4	Jeff Bagwell J. Bagwell	867	833	3,038	596	174	11	186	568	516	46	652	44	20	3,631	1,621	371	0	31	34	94	.285	.394	.534	.927	651	200	.395	135	167.1
5	Hunter Pence H. Pence	768	680	2,649	353	145	24	103	377	195	7	519	61	36	2,863	1,270	272	0	12	6	67	.290	.339	.479	.818	407	68.5	.355	117	60.4
6	Brad Ausmus B. Ausmus	746	1,001	3,113	308	127	14	31	297	305	32	491	27	16	3,514	994	172	45	19	37	117	.240	.312	.319	.631	293	-138.1	.282	64	-162.4
7	Richard Hidalgo R. Hidalgo	617	612	2,171	354	146	16	110	368	228	51	459	32	22	2,481	1,125	272	0	31	19	58	.284	.361	.518	.879	400	89.7	.373	120	65.9
8	Michael Bourn M. Bourn	552	541	2,037	302	88	29	11	134	197	10	450	193	41	2,270	731	128	20	6	8	15	.271	.337	.359	.696	243	-22.7	.312	90	-28
9	Morgan Ensberg M. Ensberg	551	673	2,072	323	99	10	105	335	319	21	395	22	18	2,435	985	214	8	15	18	56	.266	.367	.475	.843	371	72.3	.364	119	57.4
10	Adam Everett A. Everett	531	649	2,145	257	102	14	35	214	131	32	347	59	18	2,374	766	151	54	12	13	25	.248	.299	.357	.656	211	-81.2	.288	69	-95.3
11	Geoff Blum G. Blum	440	580	1,696	188	77	7	46	228	138	14	268	3	3	1,871	669	130	3	20	14	40	.259	.317	.394	.711	199	-25.3	.310	85	-35.3
12	Jose Vizcaino J. Vizcaino	385	559	1,396	154	65	13	13	133	82	4	174	9	9	1,513	515	91	24	7	14	26	.276	.316	.369	.685	148	-37	.298	74	-49.7
13	Miguel Tejada M. Tejada	378	316	1,267	175	84	4	27	152	43	17	120	12	9	1,339	551	115	1	11	6	61	.298	.327	.435	.762	164	2.8	.331	100	0.4
14	Mike Lamb M. Lamb	363	487	1,292	194	63	13	49	196	124	4	228	4	6	1,435	599	125	1	14	15	29	.281	.342	.464	.806	195	18.2	.344	106	10.9
15	Julio Lugo J. Lugo	354	366	1,320	222	60	9	28	114	120	11	295	45	24	1,483	516	97	22	10	4	24	.268	.332	.391	.723	170	-15.8	.319	84	-31.3
16	Moises Alou M. Alou	331	262	967	161	59	3	57	222	109	5	102	8	4	1,098	567	119	0	17	18	39	.342	.405	.586	.992	217	76.5	.415	144	64.6
17	Willy Taveras W. Taveras	319	311	1,122	167	32	9	4	59	59	18	192	68	20	1,224	381	45	19	6	1	10	.284	.329	.340	.668	119	-30.7	.299	77	-36.7
18	Jeff Kent J. Kent	306	275	1,045	173	73	9	49	200	88	11	181	13	5	1,158	544	131	0	14	5	36	.293	.350	.521	.870	182	38.8	.369	121	30.6
19	Chris Johnson C. Johnson	297	304	1,082	109	64	8	26	136	55	12	286	9	3	1,158	455	98	0	9	6	22	.274	.314	.421	.735	133	1.4	.319	98	-2.7
20	Jason Lane J. Lane	291	494	1,206	165	64	7	61	189	123	13	257	10	6	1,361	552	132	4	15	2	22	.241	.315	.458	.772	170	3.5	.332	98	-4
21	Jeff Keppinger J. Keppinger	276	287	982	119	56	4	17	108	82	4	76	4	4	1,088	391	77	12	8	4	33	.281	.336	.398	.735	128	1.4	.325	99	-1.4
22	Chris Burke C. Burke	254	359	1,020	148	61	5	20	94	80	28	194	31	10	1,155	385	86	21	6	1	23	.249	.319	.377	.697	122	-19.9	.309	83	-25.5
23	Daryle Ward D. Ward	249	350	930	98	56	2	41	158	67	2	191	1	3	1,007	432	99	0	8	11	18	.268	.316	.465	.780	125	0.2	.331	92	-10.1
24	Kazuo Matsui K. Matsui	239	255	922	118	47	5	15	80	75	4	148	40	9	1,033	341	67	25	7	2	7	.259	.315	.370	.685	104	-20.1	.304	82	-22
25	Mark Loretta M. Loretta	233	255	787	89	42	2	10	87	82	5	76	2	3	885	309	54	3	8	1	25	.296	.363	.393	.755	114	5.8	.338	102	1.7