The Toronto Blue Jays have crushed the most homers by a team in a game, with 10 home runs against the Orioles on September 14, 1987.

Interpreted as:

most home runs in MLB regular-season game by team ever

	TEAM	HR	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Blue Jays	10	9/14/1987	TOR	vs	BAL	W 18-3	44	18	21	2	0	18	4	0	4	0	0	48	53	12	0	0	0	1	.477	.521	1.205	1.725
2	Yankees	9	3/29/2025	NYY	vs	MIL	W 20-9	40	20	16	2	0	20	8	2	5	0	0	51	45	11	0	1	0	0	.400	.510	1.125	1.635
3	Reds	9	9/4/1999	CIN	@	PHI	W 22-3	47	22	19	3	0	22	8	1	8	0	0	56	49	12	0	0	0	0	.404	.500	1.043	1.543
4	Athletics	8	7/14/2024	OAK	@	PHI	W 18-3	40	18	15	2	1	18	5	0	5	0	1	46	43	11	0	1	0	0	.375	.435	1.075	1.510
5	Dodgers	8	7/10/2021	LAD	vs	ARI	W 22-1	44	22	21	2	1	22	8	1	4	0	0	53	49	11	0	0	0	2	.477	.566	1.114	1.680
6	Blue Jays	8	6/13/2021	TOR	@	BOS	W 18-4	44	18	20	3	0	18	4	0	7	1	0	49	47	11	0	1	0	3	.455	.490	1.068	1.558
7	Nationals	8	8/18/2019	WSH	vs	MIL	W 16-8	40	16	19	2	1	16	4	0	3	0	0	46	47	11	2	0	0	1	.475	.523	1.175	1.698
8	Diamondbacks	8	6/10/2019	ARI	@	PHI	W 13-8	40	13	14	1	0	13	6	0	9	1	0	46	39	9	0	0	0	1	.350	.435	.975	1.410
9	Twins	8	5/23/2019	MIN	@	LAA	W 16-7	43	16	17	4	0	16	6	0	7	1	0	50	45	12	0	1	0	0	.395	.460	1.047	1.507
10	Twins	8	4/20/2019	MIN	@	BAL	W 16-7	46	16	19	5	0	16	0	0	5	0	0	46	48	13	0	0	0	0	.413	.413	1.043	1.457
11	Dodgers	8	3/28/2019	LAD	vs	ARI	W 12-5	35	12	12	1	0	12	3	0	3	0	0	39	37	9	1	0	0	0	.343	.395	1.057	1.452
12	Nationals	8	7/27/2017	WSH	vs	MIL	W 15-2	42	15	19	5	0	15	5	0	9	1	0	48	48	13	1	0	0	0	.452	.511	1.143	1.653
13	Mets	8	8/24/2015	NYM	@	PHI	W 16-7	47	16	20	7	0	16	2	1	8	0	0	50	51	15	0	0	0	0	.426	.460	1.085	1.545
14	Orioles	8	6/16/2015	BAL	vs	PHI	W 19-3	39	19	17	2	0	17	8	1	7	0	0	49	43	10	0	1	0	2	.436	.531	1.103	1.633
15	Red Sox	8	9/4/2013	BOS	vs	DET	W 20-4	41	20	19	4	0	20	4	2	10	1	0	48	47	12	0	1	1	1	.463	.521	1.146	1.667
16	Blue Jays	8	8/7/2010	TOR	vs	TBR	W 17-11	43	17	20	4	0	17	6	0	4	0	0	49	48	12	0	0	0	1	.465	.531	1.116	1.647
17	Yankees	8	7/31/2007	NYY	vs	CWS	W 16-3	39	16	16	2	0	16	4	0	2	0	1	44	42	10	0	1	0	0	.410	.455	1.077	1.531
18	Tigers	8	6/18/2006	DET	@	CHC	W 12-3	39	12	13	1	0	12	2	1	6	0	0	43	38	9	1	0	0	0	.333	.381	.974	1.355
19	Braves	8	5/28/2006	ATL	@	CHC	W 13-12	51	13	18	3	0	13	4	0	18	0	0	56	45	11	1	0	0	1	.353	.400	.882	1.282
20	Rangers	8	6/30/2005	TEX	vs	LAA	W 18-5	39	18	15	3	0	17	8	0	9	0	0	47	42	11	0	0	0	0	.385	.489	1.077	1.566
21	Rangers	8	5/21/2005	TEX	vs	HOU	W 18-3	40	18	17	3	0	17	5	0	9	0	1	45	44	11	0	0	0	0	.425	.489	1.100	1.589
22	Indians	8	7/16/2004	CLE	@	SEA	W 18-6	46	18	21	5	0	18	5	3	5	0	0	55	50	13	1	0	0	0	.457	.537	1.087	1.624
23	Dodgers	8	5/23/2002	LAD	@	MIL	W 16-3	44	16	19	3	0	16	4	0	7	0	0	50	46	11	1	1	1	0	.432	.469	1.045	1.515
24	Tigers	8	6/20/2000	DET	@	TOR	W 18-6	41	18	18	3	1	18	9	0	3	0	0	50	47	12	0	0	0	4	.439	.540	1.146	1.686
25	Indians	8	4/25/1997	CLE	@	MIL	W 11-4	37	11	14	4	0	11	7	0	6	0	1	45	42	12	1	0	0	2	.378	.477	1.135	1.612