The New York Yankees launched their most home runs in a game versus the Cleveland Indians on April 14, 1974, with 6 homers.

Interpreted as:

most homeruns in a regular-season game from yankees vs guardians

	TEAM	HR	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	6	4/14/1974	NYY	@	CLE	W 9-5	35	9	9	0	0	9	6	2	6	1	1	44	27	6	1	0	1	1	.257	.395	.771	1.167
2	Yankees	5	9/17/2021	NYY	vs	CLE	W 8-0	34	8	11	0	0	8	2	0	8	0	0	36	26	5	0	0	0	1	.324	.361	.765	1.126
3	Yankees	5	4/9/2013	NYY	@	CLE	W 14-1	45	14	18	6	0	14	2	1	6	0	0	48	39	11	0	0	0	2	.400	.438	.867	1.304
4	Yankees	5	4/17/2009	NYY	vs	CLE	W 6-5	33	6	8	0	0	5	6	0	5	2	0	39	23	5	0	0	0	0	.242	.359	.697	1.056
5	Yankees	5	10/1/1980	NYY	@	CLE	W 18-7	45	18	19	3	0	16	4	0	9	1	0	51	37	8	1	1	0	1	.422	.460	.822	1.282
6	Yankees	5	8/26/1960	NYY	vs	CLE	W 7-6	44	7	14	2	0	7	4	0	9	0	0	48	31	7	0	0	0	0	.318	.375	.705	1.080
7	Yankees	5	6/19/1958	NYY	@	CLE	W 9-3	40	9	17	0	0	9	8	0	1	0	1	49	32	5	1	0	0	2	.425	.521	.800	1.321
8	Yankees	5	6/13/1927	NYY	vs	CLE	W 14-6	37	14	15	3	2	14	6	0	4	0	0	45	37	10	2				.405	.488	1.000	1.488
9	Yankees	4	7/2/2022	NYY	@	CLE	W 13-4	39	13	14	1	0	12	7	0	5	2	0	46	27	5	0	0	0	3	.359	.457	.692	1.149
10	Yankees	4	4/23/2021	NYY	@	CLE	W 5-3	32	5	6	0	0	5	4	0	7	0	0	36	18	4	0	0	0	0	.188	.278	.563	.840
11	Yankees	4	8/17/2019	NYY	vs	CLE	W 6-5	31	6	8	0	0	5	1	0	9	1	0	32	20	4	0	0	0	0	.258	.281	.645	.926
12	Yankees	4	5/8/2008	NYY	vs	CLE	W 6-3	30	6	9	2	0	6	1	0	2	0	0	31	23	6	0	0	0	2	.300	.323	.767	1.089
13	Yankees	4	8/4/2005	NYY	@	CLE	W 4-3	35	4	11	1	0	4	0	1	9	0	1	36	24	5	0	0	0	2	.314	.333	.686	1.019
14	Yankees	4	7/9/2005	NYY	vs	CLE	L 7-8	37	7	11	2	0	7	3	0	4	0	0	40	25	6	0	0	0	1	.297	.350	.676	1.026
15	Yankees	4	6/2/2001	NYY	vs	CLE	W 9-4	37	9	13	4	0	9	3	0	5	1	0	41	29	8	1	0	0	0	.351	.400	.784	1.184
16	Yankees	4	9/22/1998	NYY	vs	CLE	W 10-4	36	10	15	1	0	10	4	0	2	0	0	41	28	5	1	0	0	3	.417	.475	.778	1.253
17	Yankees	4	9/28/1977	NYY	vs	CLE	W 10-0	37	10	11	2	0	10	1	0	4	0	0	39	25	6	1	0	0	0	.297	.316	.676	.991
18	Yankees	4	7/4/1977	NYY	vs	CLE	W 7-5	33	7	9	1	0	7	2	0	3	1	0	36	22	5	1	0	1	0	.273	.314	.667	.981
19	Yankees	4	9/23/1973	NYY	@	CLE	W 9-1	39	9	14	2	0	9	5	0	8	0	0	44	28	6	0	0	0	2	.359	.432	.718	1.150
20	Yankees	4	7/13/1964	NYY	@	CLE	W 10-4	40	10	13	0	0	10	4	0	7	0	0	44	25	4	0	0	0	0	.325	.386	.625	1.011
21	Yankees	4	5/9/1964	NYY	@	CLE	W 6-2	31	6	8	1	0	6	4	0	6	0	0	35	21	5	0	0	1	4	.258	.343	.677	1.020
22	Yankees	4	7/19/1960	NYY	@	CLE	W 13-11	42	13	16	1	0	13	4	0	4	0	0	47	29	5	1	0	0	2	.381	.435	.690	1.125
23	Yankees	4	6/5/1957	NYY	@	CLE	W 13-3	43	13	16	3	0	13	2	0	7	1	0	45	31	7	0	0	0	0	.372	.400	.721	1.121
24	Yankees	4	8/31/1950	NYY	vs	CLE	W 7-5	32	7	10	0	0	7	2	0	5	0	1	34	22	4	0		0	1	.313	.353	.688	1.040
25	Yankees	4	7/21/1948	NYY	vs	CLE	W 7-3	34	7	12	1	0	6	2	0	1	0	2	38	25	5	2			0	.353	.389	.735	1.124

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Results may be incomplete. StatMuse has complete team, game-level data for home runs going back to the 1901 season.

Some of the information used here was obtained free of charge from Retrosheet.

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Wed 3/25	NYY	@	SFG	8:05 PM
Fri 3/27	NYY	@	SFG	4:35 PM
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Tue 9/16	TOR	@	TBR	1-2
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The New York Yankees launched their most home runs in a game versus the Cleveland Indians on April 14, 1974, with 6 homers.

Interpreted as:

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