Vladimir Guerrero Jr. launched the most homers by a first baseman in 2021, with 48 home runs.

	NAME	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Vladimir Guerrero Jr. V. Guerrero Jr.	48	2021	TOR	161	604	123	188	29	1	111	86	6	110	4	1	698	363	78	0	2	7	20	.311	.401	.601	1.002	145	60.4	.419	166	56.1
2	Matt Olson M. Olson	39	2021	OAK	156	565	101	153	35	0	111	88	9	113	4	1	673	305	74	0	11	12	17	.271	.371	.540	.911	117	35.7	.379	147	38.9
3	Pete Alonso P. Alonso	37	2021	NYM	152	561	81	147	27	3	94	60	12	127	3	0	637	291	67	0	4	6	20	.262	.344	.519	.863	103	25.4	.363	131	25.3
4	Max Muncy M. Muncy	36	2021	LAD	144	497	95	124	26	2	94	83	11	120	2	1	592	262	64	0	1	5	7	.249	.368	.527	.895	103	31.5	.379	140	29.9
5	Joey Votto J. Votto	36	2021	CIN	129	448	73	119	23	1	99	77	4	127	1	0	533	252	60	0	4	6	7	.266	.375	.563	.938	98	33.9	.391	140	27.4
6	Ryan Mountcastle R. Mountcastle	33	2021	BAL	144	534	77	136	23	1	89	41	4	161	4	3	586	260	57	0	7	2	12	.255	.309	.487	.796	81	10	.335	111	7.8
7	Freddie Freeman F. Freeman	31	2021	ATL	159	600	120	180	25	2	83	85	8	107	8	3	695	302	58	0	2	15	11	.300	.393	.503	.896	121	37.2	.379	136	32
8	Paul Goldschmidt P. Goldschmidt	31	2021	STL	158	603	102	177	36	2	99	67	4	136	12	0	679	310	69	0	5	2	13	.294	.365	.514	.879	115	33.2	.373	136	31.4
9	José Abreu J. Abreu	30	2021	CWS	152	566	86	148	30	2	117	61	22	143	1	0	659	272	62	0	10	3	28	.261	.351	.481	.831	101	21.5	.354	125	19.8
10	Miguel Sanó M. Sanó	30	2021	MIN	135	470	68	105	24	0	75	59	2	183	2	1	532	219	54	0	1	2	13	.223	.312	.466	.778	72	7.5	.332	111	7.4
11	Brandon Belt B. Belt	29	2021	SFG	97	325	65	89	14	2	59	48	7	103	3	2	381	194	45	0	1	3	9	.274	.378	.597	.975	75	28.9	.406	159	28.4
12	Jared Walsh J. Walsh	29	2021	LAA	144	530	70	147	34	1	98	48	4	152	2	1	585	270	64	0	3	6	7	.277	.340	.509	.850	92	20.7	.357	126	18.5
13	C.J. Cron	28	2021	COL	142	470	70	132	31	1	92	60	13	117	1	0	547	249	60	0	4	3	11	.281	.375	.530	.905	97	31	.383	125	17.7
14	Josh Bell J. Bell	27	2021	WSH	144	498	75	130	24	1	88	65	2	101	0	0	568	237	52	0	3	2	22	.261	.347	.476	.823	86	17.6	.352	119	14
15	Rhys Hoskins R. Hoskins	27	2021	PHI	107	389	64	96	29	0	71	47	5	108	3	2	443	206	56	0	2	0	7	.247	.334	.530	.864	72	18.3	.364	128	15.6
16	Bobby Dalbec B. Dalbec	25	2021	BOS	133	417	50	100	21	5	78	28	7	156	2	0	453	206	51	0	1	1	3	.240	.298	.494	.792	62	7.3	.334	106	3.3
17	Jesus Aguilar J. Aguilar	22	2021	MIA	131	449	49	117	23	0	93	46	3	93	0	0	505	206	45	0	7	4	11	.261	.329	.459	.788	69	8.1	.334	108	4.9
18	Anthony Rizzo A. Rizzo	22	2021	TOT	141	496	73	123	23	3	61	52	23	87	6	2	576	218	48	0	5	2	15	.248	.344	.440	.783	81	11.7	.339	114	10
19	Jonathan Schoop J. Schoop	22	2021	DET	156	623	85	173	30	1	84	37	6	133	2	0	674	271	53	0	8	0	15	.278	.320	.435	.755	87	5.3	.324	105	4.4
20	Trey Mancini T. Mancini	21	2021	BAL	147	556	77	142	33	1	71	51	8	143	0	0	616	240	55	0	1	4	19	.255	.326	.432	.758	80	5.8	.326	105	3.5
21	Brad Miller B. Miller	20	2021	PHI	140	331	53	75	9	3	49	45	1	112	3	0	377	150	32	0	0	2	7	.227	.321	.453	.774	51	5.3	.331	106	2.9
22	Carlos Santana C. Santana	19	2021	KCR	158	565	66	121	15	0	69	86	3	102	2	0	659	193	34	0	5	3	12	.214	.319	.342	.660	69	-11.2	.294	81	-15.3
23	Ty France T. France	18	2021	SEA	152	571	85	166	32	1	73	46	27	106	0	0	650	254	51	0	6	1	13	.291	.368	.445	.813	99	20.8	.353	129	23
24	Nathaniel Lowe N. Lowe	18	2021	TEX	157	557	75	147	24	3	72	80	2	162	8	0	642	231	45	0	3	2	13	.264	.357	.415	.771	90	12	.337	112	9.6
25	Albert Pujols A. Pujols	17	2021	TOT	109	275	29	65	3	0	50	14	5	45	2	0	296	119	20	0	2	3	14	.236	.284	.433	.717	33	-2.9	.302	89	-3.8