Chris Archer and James Shields were tied for losing the most games in 2016, with 19 games.

	NAME	L	SEASON	TM	W	L%	G	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Chris Archer C. Archer	19	2016	TBR	9	.679	33	.321	33	4.02	233	0	0	0	201.1	183	90	100	30	67	3	0	0	850	11	10.42	3.00	3.48	1.34	27.4	7.9	1.24	.296	4.47	99	3.80	92	8.18	6.9
2	James Shields J. Shields	19	2016	TOT	6	.760	33	.240	33	5.85	135	1	0	0	181.2	208	118	122	40	82	8	0	3	822	10	6.69	4.06	1.65	1.98	16.4	10.0	1.60	.302	6.04	142	6.00	143	10.30	-36.8
3	Jimmy Nelson J. Nelson	16	2016	MIL	8	.667	32	.333	32	4.62	140	0	0	0	179.1	186	92	108	25	86	17	0	2	807	8	7.03	4.32	1.63	1.25	17.3	10.7	1.52	.299	5.42	110	5.11	122	9.33	-17.6
4	R.A. Dickey	15	2016	TOR	10	.600	30	.400	29	4.46	126	0	0	0	169.2	169	84	97	28	63	6	1	0	728	5	6.68	3.34	2.00	1.49	17.3	8.7	1.37	.279	5.15	106	5.02	118	8.96	-14.7
5	Robbie Ray R. Ray	15	2016	ARI	8	.652	32	.348	32	4.90	218	0	0	0	174.1	185	95	105	24	71	6	0	4	776	8	11.25	3.67	3.07	1.24	28.1	9.1	1.47	.352	5.42	112	3.75	90	9.55	8
6	Jerad Eickhoff J. Eickhoff	14	2016	PHI	11	.560	33	.440	33	3.65	167	0	0	0	197.1	187	80	88	30	42	8	0	2	811	6	7.62	1.92	3.98	1.37	20.6	5.2	1.16	.278	4.01	89	4.18	99	8.53	0.7
7	Ricky Nolasco R. Nolasco	14	2016	TOT	8	.636	32	.364	32	4.42	144	1	1	0	197.2	202	97	104	26	44	5	0	0	817	7	6.56	2.00	3.27	1.18	17.6	5.4	1.24	.294	4.74	104	4.14	97	9.20	3.2
8	Patrick Corbin P. Corbin	13	2016	ARI	5	.722	36	.278	24	5.15	131	0	0	1	155.2	177	89	109	24	66	5	6	2	701	9	7.57	3.82	1.98	1.39	18.7	9.4	1.56	.322	6.30	118	4.83	116	10.23	-11.3
9	Doug Fister D. Fister	13	2016	HOU	12	.520	32	.480	32	4.64	115	0	0	0	180.1	195	93	98	24	62	7	0	1	779	10	5.74	3.09	1.85	1.20	14.8	8.0	1.43	.299	4.89	115	4.74	113	9.73	-11.1
10	Jaime Garcia J. Garcia	13	2016	STL	10	.565	32	.435	30	4.67	150	1	1	0	171.2	179	89	94	26	57	7	0	3	741	8	7.86	2.99	2.63	1.36	20.2	7.7	1.37	.305	4.93	114	4.48	110	9.38	-7.7
11	Tom Koehler T. Koehler	13	2016	MIA	9	.591	33	.409	33	4.33	147	0	0	0	176.2	176	85	93	22	83	5	0	7	774	9	7.49	4.23	1.77	1.12	19.0	10.7	1.47	.298	4.74	109	4.59	115	8.97	-12.1
12	Francisco Liriano F. Liriano	13	2016	TOT	8	.619	31	.381	29	4.69	168	0	0	0	163.0	157	85	98	26	85	9	0	1	731	9	9.28	4.69	1.98	1.44	23.0	11.6	1.48	.296	5.41	114	4.88	118	8.67	-13.8
13	Wade Miley W. Miley	13	2016	TOT	9	.591	30	.409	30	5.37	137	1	1	0	166.0	187	99	100	25	49	6	0	1	711	8	7.43	2.66	2.80	1.36	19.3	6.9	1.42	.328	5.42	132	4.44	105	10.14	-4.3
14	Anibal Sanchez A. Sanchez	13	2016	DET	7	.650	35	.350	26	5.87	135	0	0	0	153.1	171	100	108	30	53	5	3	1	668	7	7.92	3.11	2.55	1.76	20.2	7.9	1.46	.317	6.34	140	5.06	118	10.04	-13
15	Matt Shoemaker M. Shoemaker	13	2016	LAA	9	.591	27	.409	27	3.88	143	1	1	0	160.0	166	69	71	18	30	7	0	1	668	2	8.04	1.69	4.77	1.01	21.4	4.5	1.23	.315	3.99	95	3.51	84	9.34	12.3
16	Matt Wisler M. Wisler	13	2016	ATL	7	.650	27	.350	26	5.00	115	0	0	1	156.2	159	87	90	26	49	4	1	3	671	5	6.61	2.81	2.35	1.49	17.1	7.3	1.33	.279	5.17	121	4.84	121	9.13	-15.3
17	Tyler Duffey T. Duffey	12	2016	MIN	9	.571	26	.429	26	6.43	114	0	0	0	133.0	167	95	103	25	32	6	0	3	596	9	7.71	2.17	3.56	1.69	19.1	5.4	1.50	.339	6.97	150	4.73	109	11.30	-5.7
18	Christian Friedrich C. Friedrich	12	2016	SDP	5	.706	24	.294	23	4.80	100	0	0	0	129.1	131	69	74	13	52	2	0	2	567	7	6.96	3.62	1.92	0.90	17.6	9.2	1.41	.295	5.15	119	4.15	102	9.12	-1
19	Kevin Gausman K. Gausman	12	2016	BAL	9	.571	30	.429	30	3.61	174	0	0	0	179.2	183	72	76	28	47	5	0	1	757	8	8.72	2.35	3.70	1.40	23.0	6.2	1.28	.308	3.81	86	4.10	94	9.17	5.5
20	Hisashi Iwakuma H. Iwakuma	12	2016	SEA	16	.429	33	.571	33	4.12	147	0	0	0	199.0	218	91	95	28	46	5	0	3	836	4	6.65	2.08	3.20	1.27	17.6	5.5	1.33	.311	4.30	103	4.26	102	9.86	-2.5
21	Ubaldo Jimenez U. Jimenez	12	2016	BAL	8	.600	29	.400	25	5.44	125	1	0	1	142.1	150	86	93	16	72	3	2	1	638	5	7.90	4.55	1.74	1.01	19.6	11.3	1.56	.318	5.88	129	4.42	101	9.48	-0.7
22	Dallas Keuchel D. Keuchel	12	2016	HOU	9	.571	26	.429	26	4.55	144	1	1	0	168.0	168	85	88	20	48	2	0	1	701	9	7.71	2.57	3.00	1.07	20.5	6.8	1.29	.304	4.71	113	3.87	92	9.00	6.2
23	Mike Leake M. Leake	12	2016	STL	9	.571	30	.429	30	4.69	125	0	0	0	176.2	203	92	101	20	30	7	0	1	757	7	6.37	1.53	4.17	1.02	16.5	4.0	1.32	.318	5.15	115	3.82	94	10.34	5.1
24	Shelby Miller S. Miller	12	2016	ARI	3	.800	20	.200	20	6.15	70	1	1	0	101.0	127	69	72	14	42	2	0	3	460	3	6.24	3.74	1.67	1.25	15.2	9.1	1.67	.340	6.42	141	4.86	117	11.32	-7.7
25	Matt Moore M. Moore	12	2016	TOT	13	.480	33	.520	33	4.08	178	0	0	0	198.1	184	90	93	25	72	6	0	1	838	6	8.08	3.27	2.47	1.13	21.2	8.6	1.29	.285	4.22	101	4.16	103	8.35	-2.9