Between the 2004 and 2008 seasons, the New York Yankees had the most wins by a team, with 476 wins.

Interpreted as:

most MLB team regular-season wins from 2004 to 2008

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	476	334	.588	810	28,091	4,470	7,811	1,482	109	1,062	4,299	3,128	383	5,030	548	174	32,008	12,697	2,653	171	235	192	708	.278	.356	.452	.808
2	Red Sox	470	340	.580	810	28,150	4,391	7,828	1,744	130	952	4,188	3,319	316	5,399	380	124	32,181	12,688	2,826	106	290	232	687	.278	.357	.451	.808
3	Angels	470	340	.580	810	28,002	3,950	7,726	1,457	144	750	3,743	2,371	236	4,574	720	263	31,051	11,721	2,351	194	248	250	660	.276	.335	.419	.753
4	Cardinals	452	357	.559	809	27,780	3,945	7,620	1,460	116	883	3,753	2,696	270	4,848	382	180	31,349	11,961	2,459	360	243	304	681	.274	.342	.431	.772
5	Phillies	440	370	.543	810	28,069	4,203	7,482	1,496	176	1,025	3,997	3,137	366	5,741	582	123	32,119	12,405	2,697	319	228	345	578	.267	.345	.442	.787
6	Twins	438	373	.540	811	27,952	3,816	7,575	1,425	175	697	3,595	2,529	257	4,650	533	204	31,197	11,441	2,297	205	254	226	739	.271	.334	.409	.744
7	White Sox	433	378	.534	811	27,714	3,978	7,316	1,373	95	1,103	3,827	2,508	315	5,253	453	245	30,991	12,188	2,571	224	230	151	654	.264	.330	.440	.769
8	Indians	428	382	.528	810	28,051	4,134	7,622	1,677	135	936	3,975	2,815	369	5,721	360	184	31,669	12,377	2,748	191	243	216	635	.272	.343	.441	.785
9	Mets	428	382	.528	810	27,806	3,843	7,300	1,459	158	909	3,653	2,713	264	5,310	744	180	31,374	11,802	2,526	365	226	301	589	.263	.331	.424	.756
10	Athletics	423	386	.523	809	27,883	3,723	7,198	1,477	96	815	3,547	3,033	254	5,201	279	105	31,517	11,312	2,388	117	230	142	728	.258	.334	.406	.740
11	Astros	422	387	.522	810	27,507	3,666	7,154	1,427	147	856	3,502	2,652	313	5,206	462	195	31,107	11,443	2,430	414	221	233	624	.260	.330	.416	.746
12	Braves	421	389	.520	810	27,932	3,984	7,542	1,568	160	890	3,820	2,799	247	5,583	352	156	31,549	12,100	2,618	352	219	254	680	.270	.339	.433	.773
13	Dodgers	418	392	.516	810	27,723	3,701	7,375	1,364	173	771	3,536	2,732	264	5,041	551	218	31,242	11,398	2,308	314	209	239	669	.266	.335	.411	.746
14	Cubs	416	393	.514	809	28,030	3,815	7,592	1,571	147	930	3,628	2,439	221	5,168	425	183	31,238	12,247	2,648	344	204	215	647	.271	.332	.437	.769
15	Padres	409	402	.504	811	27,831	3,561	7,200	1,457	167	755	3,394	2,805	247	5,479	365	141	31,440	11,256	2,379	306	251	203	619	.259	.329	.404	.734
16	Blue Jays	403	406	.498	809	27,747	3,770	7,396	1,592	156	771	3,593	2,567	329	4,926	332	148	31,035	11,613	2,519	138	254	140	708	.267	.333	.419	.752
17	Rangers	402	408	.496	810	28,273	4,277	7,670	1,665	157	1,043	4,093	2,598	268	5,703	358	125	31,518	12,778	2,865	144	235	166	608	.271	.336	.452	.788
18	Tigers	400	410	.494	810	28,265	4,080	7,781	1,506	230	949	3,900	2,378	248	5,445	378	179	31,311	12,594	2,685	200	220	151	639	.275	.335	.446	.780
19	Marlins	399	410	.493	809	27,616	3,753	7,301	1,532	172	867	3,558	2,572	350	5,838	483	201	31,114	11,778	2,571	356	220	249	600	.264	.332	.426	.759
20	Brewers	396	413	.489	809	27,453	3,641	7,024	1,557	143	919	3,481	2,624	368	6,047	492	181	30,960	11,624	2,619	294	221	256	599	.256	.327	.423	.750
21	Giants	385	424	.476	809	27,561	3,568	7,204	1,488	185	699	3,380	2,614	261	4,617	399	162	31,035	11,159	2,372	387	212	374	706	.261	.329	.405	.734
22	Diamondbacks	376	434	.464	810	27,546	3,516	7,031	1,521	190	816	3,365	2,670	263	5,479	363	135	31,026	11,380	2,527	311	236	223	631	.255	.324	.413	.738
23	Reds	375	435	.463	811	27,670	3,806	7,099	1,475	102	1,024	3,639	2,920	318	6,068	455	159	31,406	11,850	2,601	309	189	233	604	.257	.332	.428	.761
24	Rockies	375	436	.462	811	27,929	3,993	7,565	1,559	186	840	3,797	2,830	293	5,753	435	183	31,727	12,016	2,585	477	198	238	635	.271	.342	.430	.772
25	Rays	361	448	.446	809	27,643	3,709	7,273	1,409	192	859	3,537	2,493	292	5,588	690	241	30,843	11,643	2,460	161	254	145	561	.263	.328	.421	.749