Since 1946, the New York Yankees have the most wins by a team, with 7,194 wins.

Interpreted as:

most MLB regular-season wins by team since 1946

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	7,194	5,394	.571	12,607	430,363	60,742	113,052	19,310	2,507	13,685	57,525	45,731	3,348	71,760	6,551	2,828	486,485	178,431	35,502	3,723	3,320	2,869	9,966	.263	.336	.415	.750
2	Dodgers	7,026	5,583	.557	12,626	428,769	56,203	110,739	18,587	2,651	11,651	52,792	43,085	3,079	74,906	8,415	3,566	484,131	169,581	32,889	6,100	3,098	3,759	9,265	.258	.328	.396	.724
3	Red Sox	6,721	5,880	.533	12,613	434,402	61,308	116,369	22,815	2,570	12,672	58,024	46,069	3,339	73,743	5,166	2,577	490,819	182,340	38,057	3,639	3,370	3,011	10,793	.268	.340	.420	.760
4	Cardinals	6,668	5,922	.530	12,614	430,759	55,998	113,129	20,234	3,147	10,069	52,557	41,269	3,241	72,210	8,186	3,632	483,557	169,864	33,450	5,121	3,167	3,784	9,539	.263	.329	.394	.724
5	Braves	6,628	5,956	.527	12,610	429,212	56,128	110,721	19,298	2,393	12,486	52,967	41,861	2,935	74,810	6,223	3,083	482,506	172,263	34,177	5,592	2,906	3,665	9,694	.258	.326	.401	.727
6	Giants	6,507	6,101	.516	12,619	429,030	55,416	109,383	18,838	2,944	11,884	52,037	42,196	3,177	75,966	6,411	3,158	482,900	169,761	33,666	5,442	3,055	4,028	9,340	.255	.324	.396	.720
7	Guardians	6,425	6,159	.511	12,602	429,587	56,739	111,520	19,627	2,358	11,972	53,548	42,335	3,348	72,443	7,045	3,410	483,056	171,779	33,957	4,400	3,386	2,569	9,795	.260	.328	.400	.728
8	Reds	6,354	6,241	.504	12,611	429,467	55,931	110,394	20,168	2,590	12,057	52,648	41,648	3,324	79,014	8,400	3,421	482,744	171,913	34,815	5,233	3,072	3,657	9,018	.257	.325	.400	.726
9	White Sox	6,254	6,338	.497	12,620	428,681	55,122	110,640	18,781	2,706	10,968	51,974	40,819	3,680	71,247	7,391	3,496	481,152	167,737	32,455	4,726	3,246	2,468	9,797	.258	.326	.391	.717
10	Phillies	6,246	6,352	.496	12,615	429,247	54,446	109,526	19,734	3,152	10,999	51,178	42,111	3,282	78,863	7,195	2,935	482,686	168,561	33,885	5,001	3,045	3,752	9,060	.255	.324	.393	.717
11	Tigers	6,220	6,381	.494	12,624	430,608	56,715	111,277	19,092	2,989	12,366	53,600	42,977	3,060	75,314	5,530	2,949	483,814	173,445	34,447	4,025	3,144	2,455	9,875	.258	.328	.403	.731
12	Orioles	6,198	6,383	.493	12,599	428,677	54,886	109,390	19,395	2,158	12,270	51,884	42,416	3,170	74,396	5,876	2,809	481,513	169,911	33,823	4,120	3,130	2,587	10,154	.255	.325	.396	.721
13	Athletics	6,122	6,480	.486	12,619	427,037	55,177	107,343	18,986	2,444	11,550	51,887	44,258	3,290	75,980	7,527	3,228	481,893	165,867	32,980	4,180	3,128	2,281	9,792	.251	.324	.388	.713
14	Twins	6,065	6,531	.482	12,614	430,884	55,840	112,006	20,086	3,033	10,654	52,550	41,576	3,451	72,906	6,086	3,104	483,016	170,120	33,773	3,916	3,189	2,670	10,302	.260	.328	.395	.723
15	Cubs	6,003	6,581	.477	12,616	430,038	54,164	109,589	19,335	2,935	11,802	51,011	40,057	3,169	78,811	6,172	3,095	481,285	170,200	34,072	5,074	2,947	3,531	9,257	.255	.321	.396	.717
16	Pirates	6,003	6,581	.477	12,607	430,090	53,147	110,886	19,662	3,380	10,005	50,021	38,346	3,344	76,682	6,912	3,294	480,195	167,323	33,047	5,276	3,139	3,710	9,308	.258	.321	.389	.710
17	Astros	5,096	5,040	.503	10,141	344,176	43,252	87,719	16,086	2,179	8,563	40,713	32,676	2,951	63,857	7,210	3,151	386,581	133,852	26,828	4,038	2,740	3,154	7,496	.255	.322	.389	.711
18	Angels	5,093	5,205	.495	10,301	349,413	44,557	89,283	15,434	1,822	9,375	41,937	32,685	2,891	63,909	6,113	3,120	391,331	136,486	26,631	3,547	2,795	2,500	7,947	.256	.322	.391	.713
19	Mets	4,899	5,227	.484	10,134	342,866	41,892	85,672	15,312	1,825	8,750	39,466	32,799	2,919	65,915	5,998	2,747	385,240	130,884	25,887	4,001	2,655	3,159	7,537	.250	.318	.382	.700
20	Rangers	4,899	5,383	.476	10,288	351,200	46,294	90,502	16,150	1,902	10,322	43,749	33,253	2,746	66,121	6,037	2,869	393,030	141,422	28,374	2,972	2,859	2,267	7,861	.258	.324	.403	.727
21	Brewers	4,405	4,595	.489	9,004	305,685	40,111	78,316	14,603	1,769	8,831	37,997	29,442	2,763	59,793	6,086	2,770	343,521	122,950	25,203	3,177	2,454	2,167	6,682	.256	.325	.402	.727
22	Nationals	4,331	4,665	.481	9,000	304,365	37,707	77,186	14,895	1,810	7,716	35,450	28,557	2,661	58,151	6,632	2,809	341,786	118,849	24,421	3,888	2,315	2,891	6,577	.254	.321	.390	.711
23	Royals	4,290	4,703	.477	8,995	307,598	39,324	80,723	15,123	2,302	7,131	37,129	26,312	2,512	52,884	7,161	2,922	341,504	121,843	24,556	2,388	2,694	1,879	6,854	.262	.323	.396	.719
24	Padres	4,217	4,789	.468	9,008	304,496	36,548	75,940	13,450	1,772	7,370	34,376	28,979	2,171	60,306	6,074	2,624	341,673	115,044	22,592	3,748	2,279	2,699	6,573	.249	.317	.378	.695
25	Blue Jays	3,855	3,856	.500	7,714	264,282	35,737	68,775	13,744	1,503	8,407	33,909	24,510	2,472	49,724	4,621	1,979	294,945	110,746	23,654	1,526	2,155	1,418	6,026	.260	.326	.419	.745