Since 1949, the New York Yankees have the most wins by a team, with 6,916 wins.

Interpreted as:

most MLB regular-season wins by team since 1949

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	6,916	5,210	.570	12,144	414,592	58,407	108,858	18,621	2,310	13,295	55,322	43,872	3,265	69,996	6,452	2,828	468,528	171,984	34,226	3,479	3,320	2,869	9,602	.263	.335	.415	.750
2	Dodgers	6,752	5,393	.556	12,159	412,907	53,984	106,542	17,857	2,481	11,422	50,760	41,056	3,015	73,085	8,113	3,566	465,820	163,627	31,760	5,744	3,098	3,759	8,975	.258	.327	.396	.724
3	Red Sox	6,438	5,700	.530	12,145	418,399	58,889	112,045	22,064	2,426	12,339	55,759	43,894	3,276	71,944	5,042	2,577	472,311	175,978	36,829	3,372	3,370	3,011	10,376	.268	.340	.421	.760
4	Cardinals	6,396	5,730	.527	12,147	414,663	53,764	108,845	19,496	2,968	9,768	50,494	39,537	3,169	70,639	8,076	3,632	465,416	163,581	32,232	4,880	3,167	3,784	9,188	.262	.329	.394	.724
5	Braves	6,370	5,754	.525	12,148	413,437	54,058	106,442	18,523	2,254	12,262	51,031	40,078	2,882	73,305	6,062	3,083	464,491	166,259	33,039	5,188	2,906	3,665	9,340	.257	.325	.402	.727
6	Giants	6,287	5,859	.518	12,155	413,219	53,194	105,259	18,232	2,810	11,378	49,938	40,575	3,108	74,207	6,285	3,158	465,184	163,245	32,420	5,227	3,055	4,028	8,992	.255	.324	.395	.719
7	Guardians	6,180	5,941	.510	12,133	413,532	54,675	107,309	18,918	2,197	11,626	51,601	40,682	3,297	70,565	6,905	3,410	465,023	165,499	32,741	4,126	3,386	2,569	9,440	.259	.328	.400	.728
8	Reds	6,150	5,984	.507	12,148	413,750	54,139	106,494	19,499	2,477	11,793	50,982	40,139	3,259	77,299	8,230	3,421	465,157	166,326	33,769	4,937	3,072	3,657	8,699	.257	.326	.402	.728
9	White Sox	6,059	6,073	.499	12,156	412,903	53,449	106,623	18,192	2,582	10,823	50,408	39,235	3,633	69,589	7,176	3,496	463,536	162,448	31,597	4,519	3,246	2,468	9,402	.258	.326	.393	.719
10	Phillies	6,049	6,087	.498	12,150	413,471	52,706	105,454	19,088	3,021	10,768	49,570	40,792	3,216	77,084	7,026	2,935	465,260	162,888	32,877	4,736	3,045	3,752	8,740	.255	.325	.394	.719
11	Orioles	6,014	6,106	.496	12,134	412,856	53,030	105,364	18,735	1,998	12,033	50,157	40,791	3,120	72,449	5,721	2,809	463,761	164,194	32,766	3,864	3,130	2,587	9,777	.255	.325	.398	.722
12	Tigers	5,965	6,174	.491	12,157	414,779	54,597	107,145	18,427	2,848	12,077	51,633	40,921	3,007	73,631	5,391	2,949	465,545	167,499	33,352	3,694	3,144	2,455	9,486	.258	.327	.404	.731
13	Athletics	5,911	6,229	.487	12,154	411,458	53,286	103,370	18,317	2,294	11,381	50,139	42,446	3,235	74,298	7,411	3,228	464,078	160,418	31,992	3,811	3,128	2,281	9,418	.251	.324	.390	.714
14	Twins	5,869	6,266	.484	12,151	415,324	54,158	108,139	19,437	2,847	10,521	51,000	39,970	3,399	71,164	5,906	3,104	465,556	164,833	32,805	3,674	3,189	2,670	9,932	.260	.328	.397	.725
15	Pirates	5,795	6,327	.478	12,140	414,298	51,145	106,813	19,053	3,230	9,681	48,164	36,568	3,284	74,865	6,766	3,294	462,338	161,369	31,964	5,049	3,139	3,710	8,947	.258	.321	.389	.710
16	Cubs	5,788	6,335	.477	12,151	414,083	52,374	105,470	18,656	2,793	11,588	49,341	38,558	3,097	77,060	6,068	3,095	463,509	164,476	33,037	4,824	2,947	3,531	8,911	.255	.321	.397	.718
17	Astros	5,096	5,040	.503	10,141	344,176	43,252	87,719	16,086	2,179	8,563	40,713	32,676	2,951	63,857	7,210	3,151	386,581	133,852	26,828	4,038	2,740	3,154	7,496	.255	.322	.389	.711
18	Angels	5,093	5,205	.495	10,301	349,413	44,557	89,283	15,434	1,822	9,375	41,937	32,685	2,891	63,909	6,113	3,120	391,331	136,486	26,631	3,547	2,795	2,500	7,947	.256	.322	.391	.713
19	Mets	4,899	5,227	.484	10,134	342,866	41,892	85,672	15,312	1,825	8,750	39,466	32,799	2,919	65,915	5,998	2,747	385,240	130,884	25,887	4,001	2,655	3,159	7,537	.250	.318	.382	.700
20	Rangers	4,899	5,383	.476	10,288	351,200	46,294	90,502	16,150	1,902	10,322	43,749	33,253	2,746	66,121	6,037	2,869	393,030	141,422	28,374	2,972	2,859	2,267	7,861	.258	.324	.403	.727
21	Brewers	4,405	4,595	.489	9,004	305,685	40,111	78,316	14,603	1,769	8,831	37,997	29,442	2,763	59,793	6,086	2,770	343,521	122,950	25,203	3,177	2,454	2,167	6,682	.256	.325	.402	.727
22	Nationals	4,331	4,665	.481	9,000	304,365	37,707	77,186	14,895	1,810	7,716	35,450	28,557	2,661	58,151	6,632	2,809	341,786	118,849	24,421	3,888	2,315	2,891	6,577	.254	.321	.390	.711
23	Royals	4,290	4,703	.477	8,995	307,598	39,324	80,723	15,123	2,302	7,131	37,129	26,312	2,512	52,884	7,161	2,922	341,504	121,843	24,556	2,388	2,694	1,879	6,854	.262	.323	.396	.719
24	Padres	4,217	4,789	.468	9,008	304,496	36,548	75,940	13,450	1,772	7,370	34,376	28,979	2,171	60,306	6,074	2,624	341,673	115,044	22,592	3,748	2,279	2,699	6,573	.249	.317	.378	.695
25	Blue Jays	3,855	3,856	.500	7,714	264,282	35,737	68,775	13,744	1,503	8,407	33,909	24,510	2,472	49,724	4,621	1,979	294,945	110,746	23,654	1,526	2,155	1,418	6,026	.260	.326	.419	.745