The Kansas City Royals gave up their most runs in a game versus the Red Sox on April 12, 1994, with 22 runs.

Interpreted as:

most runs allowed regular-season game by royals

	TEAM	R	DATE	TM		OPP	RESULT	ERA	SO	SHO	SV	IP	H	ER	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Royals	22	4/12/1994	KCR	vs	BOS	L 11-22	16.00	5	0	0	9.0	15	16	5	13	2	0	57	0	5.00	13.00	0.38	5.00	8.8	22.8	3.11	.313	22.00	15.00
2	Royals	21	8/25/2004	KCR	@	ANA	L 6-21	21.38	6	0	0	8.0	22	19	3	4	2	0	52	1	6.75	4.50	1.50	3.38	11.5	7.7	3.25	.514	23.63	24.75
3	Royals	21	6/18/2000	KCR	vs	OAK	L 3-21	20.00	8	0	0	9.0	21	20	4	10	0	0	57	1	8.00	10.00	0.80	4.00	14.0	17.5	3.44	.486	21.00	21.00
4	Royals	19	8/26/2019	KCR	vs	OAK	L 4-19	19.00	8	0	0	9.0	22	19	4	6	0	0	55	1	8.00	6.00	1.33	4.00	14.5	10.9	3.11	.486	19.00	22.00
5	Royals	19	5/16/2011	KCR	vs	CLE	L 1-19	19.00	5	0	0	9.0	20	19	1	8	0	0	53	1	5.00	8.00	0.63	1.00	9.4	15.1	3.11	.487	19.00	20.00
6	Royals	19	7/26/2010	KCR	vs	MIN	L 1-19	19.00	12	0	0	9.0	20	19	2	6	1	0	52	1	12.00	6.00	2.00	2.00	23.1	11.5	2.89	.581	19.00	20.00
7	Royals	19	7/21/2008	KCR	vs	DET	L 4-19	19.00	9	0	0	9.0	18	19	2	9	0	0	54	1	9.00	9.00	1.00	2.00	16.7	16.7	3.00	.471	19.00	18.00
8	Royals	19	9/27/2003	KCR	vs	CWS	L 3-19	15.00	8	0	0	9.0	21	15	0	5	1	0	55	2	8.00	5.00	1.60	0.00	14.5	9.1	2.89	.512	19.00	21.00
9	Royals	19	7/28/1973	KCR	vs	CAL	L 8-19	18.00	8	0	0	9.0	21	18	3	7	0	1	54	0	8.00	7.00	1.14	3.00	14.8	13.0	3.11	.500	19.00	21.00
10	Royals	18	5/16/2003	KCR	vs	TOR	L 1-18	18.00	9	0	0	9.0	22	18	1	5	2	0	56	5	9.00	5.00	1.80	1.00	16.1	8.9	3.00	.538	18.00	22.00
11	Royals	18	7/17/1998	KCR	@	SEA	L 5-18	20.25	3	0	0	8.0	22	18	3	5	0	0	48	1	3.38	5.63	0.60	3.38	6.3	10.4	3.38	.514	20.25	24.75
12	Royals	18	9/18/1986	KCR	@	CAL	L 3-18	20.25	8	0	0	8.0	20	18	3	9	1	1	53	1	9.00	10.13	0.89	3.38	15.1	17.0	3.63	.531	20.25	22.50
13	Royals	18	4/13/1983	KCR	vs	BOS	L 4-18	11.00	6	0	0	9.0	20	11	1	6	3	0	56	1	6.00	6.00	1.00	1.00	10.7	10.7	2.89	.475	18.00	20.00
14	Royals	18	9/5/1982	KCR	vs	NYY	L 7-18	15.00	2	0	0	9.0	15	15	4	8	0	0	51	1	2.00	8.00	0.25	4.00	3.9	15.7	2.56	.297	18.00	15.00
15	Royals	18	9/10/1976	KCR	@	MIN	L 3-18	16.88	2	0	0	8.0	18	15	1	14	0	1	55	2	2.25	15.75	0.14	1.13	3.6	25.5	4.00	.447	20.25	20.25
16	Royals	17	4/10/2022	KCR	vs	CLE	L 3-17	17.00	10	0	0	9.0	22	17	2	4	1	0	53	0	10.00	4.00	2.50	2.00	18.9	7.5	2.89	.556	17.00	22.00
17	Royals	17	9/2/2017	KCR	@	MIN	L 0-17	19.13	4	0	0	8.0	14	17	3	9	0	0	46	0	4.50	10.13	0.44	3.38	8.7	19.6	2.88	.367	19.13	15.75
18	Royals	17	5/10/2007	KCR	vs	OAK	L 3-17	15.00	8	0	0	9.0	18	15	6	7	0	0	54	1	8.00	7.00	1.14	6.00	14.8	13.0	2.78	.364	17.00	18.00
19	Royals	17	5/27/2004	KCR	vs	DET	L 7-17	17.00	5	0	0	9.0	27	17	2	3	0	0	55	0	5.00	3.00	1.67	2.00	9.1	5.5	3.33	.556	17.00	27.00
20	Royals	17	10/1/1995	KCR	@	CLE	L 7-17	18.00	7	0	0	8.0	19	16	2	5	0	0	48	0	7.88	5.63	1.40	2.25	14.6	10.4	3.00	.500	19.13	21.38
21	Royals	17	7/19/1991	KCR	vs	DET	L 0-17	13.00	13	0	0	9.0	16	13	1	8	0	0	52	3	13.00	8.00	1.63	1.00	25.0	15.4	2.67	.500	17.00	16.00
22	Royals	17	4/20/1990	KCR	@	TOR	L 6-17	18.00	2	0	0	8.0	19	16	5	7	1	0	51	1	2.25	7.88	0.29	5.63	3.9	13.7	3.25	.389	19.13	21.38
23	Royals	17	7/23/1989	KCR	vs	CLE	L 5-17	15.00	3	0	0	9.0	16	15	2	7	1	1	50	0	3.00	7.00	0.43	2.00	6.0	14.0	2.56	.378	17.00	16.00
24	Royals	17	7/16/1983	KCR	@	CLE	L 3-17	18.00	3	0	0	8.0	20	16	4	5	0	0	46	1	3.38	5.63	0.60	4.50	6.5	10.9	3.13	.471	19.13	22.50
25	Royals	17	8/20/1979	KCR	vs	NYY	L 4-17	17.00	1	0	0	9.0	18	17	3	4	0	0	49	1	1.00	4.00	0.25	3.00	2.0	8.2	2.44	.366	17.00	18.00