The Chicago Cubs scored the most runs by a team in a game in 1922, with 26 runs versus the Phillies on August 25, 1922.

Interpreted as:

most runs by a team in a regular-season game in 1922

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	AVG	OBP	SLG	OPS
1	Cubs	26	8/25/1922	CHC	vs	PHN	W 26-23	46	25	8	0	3	24	10	1	4	1	0	59	42	11	2	.543	.632	.913	1.545
2	Phillies	23	8/25/1922	PHN	@	CHC	L 23-26	52	26	4	2	0	19	11	0	5	1	1	66	34	6	3	.500	.587	.654	1.241
3	White Sox	19	8/15/1922	CWS	@	BSA	W 19-11	49	25	3	1	0	18	3	0	4	0	0	56	30	4	4	.510	.538	.612	1.151
4	Pirates	19	8/8/1922	PIT	@	PHN	W 19-8	52	27	4	0	3	17	2	1	3	1	0	55	40	7	0	.519	.545	.769	1.315
5	Giants	19	8/5/1922	NYG	vs	CHC	W 19-7	47	27	6	4	0	17	4	1	2	1	2	53	41	10	1	.574	.615	.872	1.488
6	Giants	19	7/10/1922	NYG	@	PIT	W 19-2	53	28	4	4	1	18	2	0	5	2	0	56	43	9	1	.528	.545	.811	1.357
7	Cardinals	19	5/15/1922	SLN	vs	PHN	W 19-7	46	23	4	4	1	18	3	1	2	1	0	51	38	9	1	.500	.540	.826	1.366
8	Senators	18	7/29/1922	WSH	@	CLE	W 18-6	47	21	7	1	1	17	6	0	4	0	0	56	33	9	3	.447	.509	.702	1.212
9	Reds	17	9/2/1922	CIN	@	CHC	W 17-5	45	21	3	1	2	14	4	0	0	1	1	52	32	6	3	.467	.510	.711	1.221
10	Tigers	17	8/22/1922	DET	@	PHA	W 17-3	43	17	5	1	2	13	5	1	4	0	0	51	30	8	2	.395	.469	.698	1.167
11	Giants	17	8/18/1922	NYG	@	CHC	W 17-11	38	12	4	0	1	15	9	3	4	0	0	52	19	5	2	.316	.480	.500	.980
12	Pirates	17	8/7/1922	PIT	@	PHN	W 17-10	48	22	6	1	1	17	3	0	3	0	1	53	33	8	2	.458	.490	.688	1.178
13	Indians	17	8/1/1922	CLE	vs	WSH	W 17-3	42	21	8	2	1	17	7	0	1	1	1	49	36	11	0	.500	.571	.857	1.429
14	Indians	17	4/18/1922	CLE	vs	SLA	W 17-2	44	22	9	0	0	17	5	0	2	2	0	50	31	9	1	.500	.551	.705	1.256
15	Athletics	17	4/18/1922	PHA	@	WSH	W 17-2	42	18	4	1	0	16	7	1	5	3	0	55	24	5	5	.429	.520	.571	1.091
16	Giants	17	4/15/1922	NYG	vs	BKN	W 17-10	41	20	1	2	0	12	5	2	3	2	0	50	25	3	2	.488	.563	.610	1.172
17	Browns	16	9/9/1922	SLA	vs	DET	W 16-0	43	20	3	5	1	15	4	2	3	0	0	49	36	9	0	.465	.531	.837	1.368
18	Tigers	16	8/21/1922	DET	@	BSA	W 16-3	42	19	3	2	0	13	4	2	1	2	0	50	26	5	2	.452	.521	.619	1.140
19	Cubs	16	8/13/1922	CHC	@	SLN	W 16-5	44	19	4	3	0	15	5	0	2	2	0	54	29	7	5	.432	.490	.659	1.149
20	Robins	16	8/10/1922	BKN	vs	CHC	W 16-1	43	18	3	1	1	13	3	3	0	1	0	49	26	5	0	.419	.490	.605	1.094
21	Browns	16	8/7/1922	SLA	vs	WSH	W 16-1	42	19	5	2	3	14	3	0	3	1	0	47	37	10	2	.452	.489	.881	1.370
22	Tigers	16	7/17/1922	DET	@	BSA	W 16-7	39	16	2	0	1	11	5	0	0	1	0	50	21	3	6	.410	.477	.538	1.016
23	Giants	16	5/30/1922	NYG	@	PHN	W 16-7	48	25	8	0	2	16	4	0	1	1	2	52	39	10	0	.521	.558	.813	1.370
24	Reds	15	9/26/1922	CIN	@	PHN	W 15-8	47	23	6	0	1	14	2	1	1	1	1	51	32	7	1	.489	.520	.681	1.201
25	Red Sox	15	9/21/1922	BSA	@	CLE	W 15-5	37	15	1	1	1	14	12	1	3	0	0	52	21	3	2	.405	.560	.568	1.128