The Chicago Cubs have the highest run differential by a team in wins this season, with a differential of 167 runs.

Interpreted as:

most runs differential in wins this regular season

	TEAM	DIFF	W	SEASON	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	167	35	2025	0	1.000	35	1,268	272	383	77	12	65	267	147	12	258	55	6	1,447	679	154	5	15	5	15	.302	.376	.535	.911
2	Yankees	155	35	2025	0	1.000	35	1,207	241	345	82	6	67	234	156	19	293	25	8	1,401	640	155	1	18	13	19	.286	.371	.530	.902
3	Tigers	151	38	2025	0	1.000	38	1,308	247	373	68	3	52	236	134	23	315	15	4	1,480	603	123	3	12	3	24	.285	.359	.461	.820
4	Dodgers	139	35	2025	0	1.000	35	1,207	248	350	60	8	65	238	156	15	271	27	7	1,396	621	133	2	16	10	24	.290	.374	.514	.888
5	Reds	124	29	2025	0	1.000	29	996	199	295	57	3	47	191	119	13	236	28	8	1,139	499	107	2	9	5	20	.296	.376	.501	.877
6	Brewers	123	30	2025	0	1.000	30	1,000	186	265	50	4	37	173	123	11	220	54	8	1,157	434	91	13	10	8	13	.265	.349	.434	.783
7	Cardinals	120	32	2025	0	1.000	32	1,078	201	311	70	4	39	192	113	17	230	21	8	1,225	506	113	3	14	5	17	.288	.361	.469	.830
8	Red Sox	117	28	2025	0	1.000	28	995	195	297	69	4	50	186	112	8	216	27	10	1,123	524	123	3	5	6	11	.298	.372	.527	.899
9	Mets	112	35	2025	0	1.000	35	1,173	191	328	75	10	49	184	113	22	254	29	7	1,325	570	134	1	16	8	29	.280	.350	.486	.836
10	Twins	109	31	2025	0	1.000	31	1,060	179	293	54	4	43	171	95	21	240	17	6	1,184	484	101	1	7	4	21	.276	.346	.457	.802
11	Rays	109	29	2025	0	1.000	29	1,001	185	280	54	1	41	177	102	10	237	55	6	1,123	459	96	0	10	0	14	.280	.349	.459	.808
12	Padres	109	32	2025	0	1.000	32	1,070	184	301	54	3	39	168	122	6	214	32	7	1,217	478	96	9	10	5	18	.281	.355	.447	.802
13	Phillies	108	36	2025	0	1.000	36	1,227	213	345	65	6	48	200	139	14	260	41	8	1,398	566	119	5	13	3	24	.281	.358	.461	.819
14	Astros	103	31	2025	0	1.000	31	1,035	169	300	50	5	39	162	98	18	214	18	10	1,166	477	94	5	10	5	30	.290	.358	.461	.819
15	Mariners	103	30	2025	0	1.000	30	1,032	184	276	46	1	53	179	123	14	259	25	8	1,183	483	100	6	8	1	17	.267	.351	.468	.819
16	Giants	99	32	2025	0	1.000	32	1,068	185	274	57	9	38	174	132	9	270	20	8	1,224	463	104	7	8	4	16	.257	.341	.434	.775
17	Blue Jays	97	29	2025	0	1.000	29	997	163	290	51	1	33	156	104	11	175	19	5	1,136	442	85	10	14	6	16	.291	.360	.443	.803
18	Rangers	95	28	2025	0	1.000	28	901	143	234	37	2	41	139	87	12	201	27	5	1,009	398	80	0	9	3	19	.260	.330	.442	.772
19	Guardians	88	30	2025	0	1.000	30	990	161	257	48	5	36	152	117	14	237	28	6	1,143	423	89	5	17	5	18	.260	.341	.427	.768
20	Royals	86	30	2025	0	1.000	30	1,025	140	299	62	5	24	140	75	10	182	33	12	1,134	443	91	9	15	6	13	.292	.341	.432	.774
21	Diamondbacks	83	27	2025	0	1.000	27	895	159	246	62	5	42	156	114	13	198	37	7	1,046	444	109	7	17	5	17	.275	.359	.496	.855
22	Athletics	82	23	2025	0	1.000	23	826	136	244	47	5	33	129	66	6	178	12	5	906	400	85	2	6	2	17	.295	.350	.484	.834
23	Braves	81	26	2025	0	1.000	26	911	153	264	45	2	35	148	94	11	193	18	6	1,028	418	82	5	7	4	19	.290	.361	.459	.820
24	White Sox	80	18	2025	0	1.000	18	592	115	158	38	1	22	114	72	5	137	23	0	680	264	61	4	7	1	3	.267	.348	.446	.794
25	Nationals	78	27	2025	0	1.000	27	929	178	264	58	8	37	168	85	18	201	32	10	1,048	449	103	7	9	2	10	.284	.353	.483	.836