Between the 2018 and 2022 seasons, Mookie Betts scored the most runs, with 521 runs.

Interpreted as:

most runs by a player from 2018 to 2022

	NAME	R	G	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Mookie Betts M. Betts	521	605	2,374	697	165	17	135	339	325	32	420	78	18	2,755	1,301	317	0	24	17	31	.294	.383	.548	.931	505	174.1	.392	149	163.3
2	Freddie Freeman F. Freeman	495	698	2,641	819	173	11	126	455	377	29	505	39	12	3,064	1,392	310	0	17	57	51	.310	.400	.527	.927	558	190.5	.390	146	173.9
3	Marcus Semien M. Semien	456	697	2,809	731	157	17	126	370	292	10	549	68	23	3,134	1,300	300	2	21	3	42	.260	.330	.463	.793	438	61.8	.338	116	62.6
4	Trea Turner T. Turner	453	651	2,665	802	152	22	99	348	220	19	522	149	26	2,920	1,295	273	2	14	8	49	.301	.357	.486	.843	458	108.6	.360	126	95.8
5	Paul Goldschmidt P. Goldschmidt	431	686	2,545	740	150	8	139	415	351	18	659	30	5	2,927	1,323	297	0	13	16	42	.291	.379	.520	.899	512	160.2	.382	144	155.8
6	Francisco Lindor F. Lindor	431	647	2,577	688	136	12	124	363	257	30	475	79	27	2,895	1,220	272	10	21	24	44	.267	.338	.473	.811	416	69.2	.344	119	66.5
7	Juan Soto J. Soto	430	617	2,136	612	116	10	125	374	508	10	448	38	14	2,666	1,123	251	1	11	54	56	.287	.424	.526	.950	512	191.4	.401	153	178.4
8	Christian Yelich C. Yelich	426	606	2,237	633	114	17	115	337	352	24	604	84	14	2,624	1,126	246	1	10	30	40	.283	.385	.503	.888	451	136.3	.377	137	123.8
9	Jose Altuve J. Altuve	425	596	2,354	685	136	6	108	293	245	24	378	48	16	2,639	1,157	250	5	11	9	63	.291	.362	.492	.854	424	107.6	.365	136	111.5
10	José Ramírez J. Ramírez	424	653	2,432	658	163	18	144	463	330	26	366	115	24	2,815	1,289	325	0	27	48	30	.271	.360	.530	.890	467	129.9	.371	138	128.6
11	Bryce Harper B. Harper	406	614	2,171	594	149	5	135	396	424	22	611	60	15	2,646	1,158	289	3	26	58	47	.274	.393	.533	.927	475	155.8	.387	142	140.1
12	Rafael Devers R. Devers	405	631	2,475	699	173	7	129	425	211	20	564	21	16	2,718	1,273	309	1	11	31	52	.282	.342	.514	.857	427	99.2	.359	124	79.7
13	Manny Machado M. Machado	401	681	2,585	735	136	9	145	447	287	11	504	46	12	2,908	1,324	290	0	25	45	81	.284	.355	.512	.867	464	115.3	.364	134	118.5
14	J.D. Martinez	399	637	2,458	717	171	8	130	423	270	18	638	9	1	2,770	1,294	309	0	24	30	82	.292	.363	.526	.889	466	132.9	.373	134	113
15	Charlie Blackmon C. Blackmon	398	640	2,471	710	132	25	96	354	204	38	482	23	11	2,736	1,180	253	5	18	12	43	.287	.349	.478	.826	412	83.3	.352	107	23.9
16	DJ LeMahieu	398	598	2,394	697	117	7	73	294	241	14	358	22	12	2,672	1,047	197	4	19	2	59	.291	.357	.437	.794	385	63.4	.343	116	54
17	Whit Merrifield W. Merrifield	398	681	2,729	778	166	17	58	296	196	19	461	133	32	2,977	1,152	241	2	31	8	46	.285	.334	.422	.756	382	23.3	.325	103	10.8
18	Aaron Judge A. Judge	397	547	2,012	579	95	1	164	373	336	18	658	31	10	2,382	1,168	260	0	16	28	56	.288	.392	.581	.972	464	179.9	.407	165	182.1
19	Ronald Acuña Jr. R. Acuña Jr.	394	514	1,983	550	102	7	120	296	261	38	582	107	32	2,294	1,026	229	0	12	14	23	.277	.370	.517	.887	391	114.9	.376	135	99.8
20	Alex Bregman A. Bregman	393	601	2,197	607	155	4	113	385	370	38	324	17	7	2,631	1,109	272	0	26	10	57	.276	.386	.505	.891	456	141.1	.380	145	145.4
21	Xander Bogaerts X. Bogaerts	392	641	2,416	726	177	4	105	400	271	23	496	33	7	2,737	1,226	286	0	27	12	55	.300	.373	.507	.880	461	132.1	.373	134	112.5
22	Nolan Arenado N. Arenado	383	664	2,510	720	154	8	151	462	252	17	403	12	7	2,809	1,343	313	1	29	35	72	.287	.352	.535	.887	465	127.4	.370	127	93.3
23	George Springer G. Springer	383	524	2,024	550	93	10	122	325	246	27	452	31	11	2,312	1,029	225	0	15	3	40	.272	.356	.508	.864	378	100.6	.367	136	102.5
24	Matt Chapman M. Chapman	382	644	2,339	564	129	15	124	332	287	35	719	7	7	2,681	1,095	268	0	20	1	45	.241	.330	.468	.799	380	58.1	.341	121	67.4
25	Trevor Story T. Story	381	597	2,304	632	149	20	123	362	214	28	666	98	23	2,562	1,190	292	0	16	10	36	.274	.341	.516	.858	406	97.2	.361	114	46.6