The Seattle Mariners had the most runs per game by a team on the road in 2000, with 6.04.

	TEAM	R/G	R	G	SEASON	W%	W	L	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mariners	6.04	489	81	2000	.543	44	37	2,872	831	176	15	106	470	363	21	519	48	37	3,315	1,355	297	30	29	18	69	.289	.370	.472	.842
2	Athletics	6.01	481	80	2000	.550	44	36	2,877	792	162	12	113	464	368	26	595	25	10	3,297	1,317	287	10	16	17	68	.275	.361	.458	.819
3	Giants	5.85	474	81	2000	.519	42	39	2,867	784	160	18	116	455	379	31	576	38	20	3,345	1,328	294	38	30	25	73	.273	.361	.463	.824
4	Indians	5.64	457	81	2000	.519	42	39	2,885	808	164	15	99	425	334	26	557	42	16	3,292	1,299	278	21	26	13	67	.280	.357	.450	.807
5	White Sox	5.6	454	81	2000	.605	49	32	2,909	813	170	13	91	430	268	26	528	62	24	3,257	1,282	274	30	24	15	75	.279	.343	.441	.784
6	Cardinals	5.54	449	81	2000	.556	45	36	2,824	764	146	11	111	425	307	50	655	31	30	3,246	1,265	268	36	29	18	66	.271	.349	.448	.797
7	Dodgers	5.44	441	81	2000	.519	42	39	2,832	746	152	17	103	418	363	26	535	45	24	3,283	1,241	272	35	27	17	66	.263	.349	.438	.788
8	Astros	5.35	433	81	2000	.407	33	48	2,853	785	131	11	114	414	332	38	585	57	20	3,283	1,280	256	29	31	27	90	.275	.355	.449	.804
9	Royals	5.28	428	81	2000	.432	35	46	2,881	786	136	10	66	400	261	25	471	63	24	3,230	1,140	212	26	37	11	64	.273	.335	.396	.730
10	Blue Jays	5.26	426	81	2000	.469	38	43	2,911	794	150	12	110	411	271	27	570	50	18	3,245	1,298	272	14	22	16	67	.273	.338	.446	.784
11	Tigers	5.19	420	81	2000	.444	36	45	2,901	778	147	17	108	399	264	24	554	40	19	3,227	1,283	272	20	18	10	72	.268	.332	.442	.775
12	Yankees	5.15	417	81	2000	.531	43	38	2,858	784	152	13	88	397	292	21	536	49	27	3,207	1,226	253	10	26	23	72	.274	.343	.429	.772
13	Angels	5.12	415	81	2000	.444	36	45	2,886	786	163	23	106	400	293	23	544	45	29	3,245	1,313	292	23	20	22	70	.272	.342	.455	.797
14	Mets	5.12	415	81	2000	.481	39	42	2,844	749	140	13	105	389	347	27	534	42	27	3,283	1,230	258	38	27	19	65	.263	.346	.432	.779
15	Cubs	5.02	407	81	2000	.333	27	54	2,849	721	149	14	99	386	317	28	574	42	14	3,261	1,195	262	40	27	16	60	.253	.331	.419	.750
16	Orioles	5	405	81	2000	.370	30	51	2,896	786	179	14	94	381	254	26	464	66	37	3,219	1,275	287	15	28	18	82	.271	.333	.440	.773
17	Braves	5	405	81	2000	.543	44	37	2,823	744	142	13	95	385	293	34	549	72	30	3,208	1,197	250	38	20	18	67	.264	.338	.424	.762
18	Padres	4.98	403	81	2000	.432	35	46	2,836	735	148	22	85	388	309	24	586	62	23	3,216	1,182	255	20	27	24	76	.259	.334	.417	.751
19	Red Sox	4.91	398	81	2000	.531	43	38	2,889	749	149	13	101	384	312	22	534	26	17	3,267	1,227	263	23	21	17	56	.259	.334	.425	.759
20	Pirates	4.9	397	81	2000	.395	32	49	2,890	788	153	11	82	380	287	32	508	42	26	3,263	1,209	246	33	21	23	77	.273	.343	.418	.761
21	Reds	4.77	386	81	2000	.519	42	39	2,882	762	146	20	102	371	255	36	533	49	17	3,230	1,254	268	30	27	35	62	.264	.329	.435	.764
22	Diamondbacks	4.75	385	81	2000	.469	38	43	2,798	703	137	19	95	367	264	28	507	53	23	3,149	1,163	251	34	25	19	61	.251	.319	.416	.735
23	Devil Rays	4.74	384	81	2000	.407	33	48	2,836	739	115	10	86	365	262	25	546	50	25	3,171	1,132	211	26	22	10	65	.261	.326	.399	.725
24	Brewers	4.67	383	82	2000	.383	31	50	2,847	732	164	8	99	369	305	28	653	41	28	3,228	1,209	271	25	23	25	75	.257	.333	.425	.757
25	Rangers	4.67	378	81	2000	.358	29	52	2,868	780	160	18	69	356	259	16	509	41	23	3,186	1,183	247	22	21	20	79	.272	.333	.412	.746