Since 1901, the Philadelphia Phillies have put up the most runs by a team in a loss, with 23 runs versus the Cubs on August 25, 1922.

Interpreted as:

most runs scored in a regular-season loss since 1901

	TEAM	R	L	DATE	TM		OPP	RESULT	W	L%	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Phillies	23	1	8/25/1922	PHN	@	CHC	L 23-26	0	1.000	52	26	4	2	0	19	11	0	5	1	1	66	34	6	3				.500	.587	.654	1.241
2	Cubs	22	1	5/17/1979	CHC	vs	PHI	L 22-23	0	1.000	56	26	3	1	6	22	3	0	4	0	0	59	49	10	0	0	0	2	.464	.492	.875	1.367
3	Rangers	17	1	8/12/2008	TEX	@	BOS	L 17-19	0	1.000	47	20	7	0	1	17	3	1	6	0	0	53	30	8	0	2	0	0	.426	.453	.638	1.091
4	Marlins	17	1	7/4/2008	FLA	@	COL	L 17-18	0	1.000	47	22	7	0	2	17	6	2	4	0	0	56	35	9	1	0	1	1	.468	.545	.745	1.290
5	Phillies	17	1	8/3/1969	PHI	vs	CIN	L 17-19	0	1.000	47	21	4	1	3	17	4	0	6	1	0	51	36	8	0	0	1	2	.447	.490	.766	1.256
6	Indians	17	1	7/10/1932	CLE	vs	PHA	L 17-18	0	1.000	83	33	9	0	1	16	10	0	7	1	0	95	45	10	2				.398	.462	.542	1.005
7	Pirates	16	1	8/1/2025	PIT	@	COL	L 16-17	0	1.000	43	18	2	0	2	16	9	1	9	0	0	53	26	4	0	0	0	2	.419	.528	.605	1.133
8	Athletics	16	1	5/5/2000	OAK	@	TEX	L 16-17	0	1.000	43	16	3	0	5	16	8	0	8	0	1	51	34	8	0	0	0	0	.372	.471	.791	1.261
9	Tigers	16	1	9/14/1998	DET	vs	CWS	L 16-17	0	1.000	58	22	4	1	3	16	1	0	10	1	0	60	37	8	0	1	1	0	.379	.383	.638	1.021
10	Cubs	16	1	4/17/1976	CHC	vs	PHI	L 16-18	0	1.000	48	19	5	0	3	16	6	3	7	0	0	58	33	8	1	0	1	1	.396	.491	.688	1.179
11	Giants	16	1	5/23/1970	SFG	vs	SDP	L 16-17	0	1.000	60	23	2	0	4	16	10	0	12	1	2	76	37	6	6	0	3	1	.383	.471	.617	1.088
12	Phillies	16	1	9/23/1930	PHN	vs	SLN	L 16-19	0	1.000	44	16	4	0	1	13	6	0	7	0	0	50	23	5	0				.364	.440	.523	.963
13	Phillies	16	1	5/18/1929	PHN	vs	BKN	L 16-20	0	1.000	41	17	6	0	2	16	12	0	6	2	0	53	29	8	0				.415	.547	.707	1.254
14	Tigers	15	1	5/8/2004	DET	@	TEX	L 15-16	0	1.000	45	16	3	0	1	15	6	1	7	1	0	53	22	4	1	0	0	0	.356	.442	.489	.931
15	Cubs	15	1	5/14/2000	CHC	@	MON	L 15-16	0	1.000	46	21	1	0	3	14	4	1	9	6	0	51	31	4	0	0	0	0	.457	.510	.674	1.184
16	Dodgers	15	1	6/30/1996	LAD	@	COL	L 15-16	0	1.000	44	18	2	1	6	15	6	0	12	2	0	51	40	9	0	1	0	0	.409	.471	.909	1.380
17	Cubs	15	1	9/24/1985	CHC	vs	MON	L 15-17	0	1.000	46	20	2	0	3	15	4	0	4	1	1	51	31	5	0	1	0	0	.435	.471	.674	1.145
18	Reds	15	1	7/28/1977	CIN	@	CHC	L 15-16	0	1.000	58	19	5	0	5	14	10	0	12	6	0	69	39	10	1	0	4	2	.328	.426	.672	1.099
19	Cardinals	15	1	7/1/1956	STL	vs	CIN	L 15-19	0	1.000	52	23	2	0	3	14	7	1	3	1	0	60	34	5	0	0	0	1	.442	.517	.654	1.171
20	White Sox	15	1	7/29/1934	CWS	vs	DET	L 15-16	0	1.000	44	19	3	1	3	14	6	0	3	0	0	50	33	7	0				.432	.500	.750	1.250
21	Cardinals	15	1	7/6/1934	SLN	vs	CIN	L 15-16	0	1.000	43	16	5	1	1	15	11	0	9	0	0	54	26	7	0			0	.372	.500	.605	1.105
22	Phillies	15	1	7/24/1930	PHN	vs	CHC	L 15-19	0	1.000	42	17	3	0	0	15	8	0	5	0	0	51	20	3	1				.405	.500	.476	.976
23	Phillies	15	1	7/23/1930	PHN	vs	PIT	L 15-16	0	1.000	62	27	6	0	5	15	5	0	6	0	0	68	48	11	1				.435	.478	.774	1.252
24	Giants	15	1	4/29/1930	NYG	vs	BKN	L 15-19	0	1.000	47	19	1	1	3	15	3	0	5	0	0	50	31	5	0				.404	.440	.660	1.100
25	Robins	15	1	4/23/1930	BKN	@	PHN	L 15-16	0	1.000	41	17	5	0	0	14	6	2	2	0	0	50	22	5	1				.415	.510	.537	1.047